A Review of the Current State of the Art of Polyether Ether Ketone (PEEK) Composite Based 3D-Printed Biomedical Scaffolds

Q2 Engineering Designs Pub Date : 2023-11-10 DOI:10.3390/designs7060128

Rajesh Surendran, Sithara Sreenilayam Pavithran, Anugop Balachandran, Sony Vijayan, Kailasnath Madanan, Dermot Brabazon

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Abstract

Three-dimensional printing or additive manufacturing (AM) has enabled innovative advancements in tissue engineering through scaffold development. The use of scaffolds, developed by using AM technology for tissue repair (like cartilage and bone), could enable the growth of several cell types on the same implant. Scaffolds are 3D-printed using polymer-based composites. polyether ether ketone (PEEK)-based composites are ideal for scaffold 3D printing due to their excellent biocompatibility and mechanical properties resembling human bone. It is therefore considered to be the next-generation bioactive material for tissue engineering. Despite several reviews on the application of PEEK in biomedical fields, a detailed review of the recent progress made in the development of PEEK composites and the 3D printing of scaffolds has not been published. Therefore, this review focuses on the current status of technological developments in the 3D printing of bone scaffolds using PEEK-based composites. Furthermore, this review summarizes the challenges associated with the 3D printing of high-performance scaffolds based on PEEK composites.

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聚醚醚酮(PEEK)复合材料3d打印生物医学支架研究进展

三维打印或增材制造(AM)通过支架开发使组织工程的创新进步成为可能。利用AM技术开发的用于组织修复(如软骨和骨)的支架，可以在同一植入物上生长多种细胞类型。支架是用聚合物基复合材料3d打印的。聚醚醚酮(PEEK)基复合材料具有优异的生物相容性和类似人骨的机械性能，是支架3D打印的理想选择。因此，它被认为是下一代组织工程的生物活性材料。尽管对PEEK在生物医学领域的应用进行了多次综述，但对PEEK复合材料的发展和3D打印支架的最新进展尚未发表详细的综述。因此，本文重点综述了peek基复合材料骨支架3D打印技术的发展现状。此外，本综述总结了基于PEEK复合材料的高性能支架3D打印相关的挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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