PHYSICAL-CHEMICAL ANALYSIS OF POLYMER NANOCAPSULES CONTAINING COPAÍBA (Copaifera spp.) AND ANDIROBA (Carapa guianensis Aubl.) VEGETABLE OILS

Multidisciplinary Sciences Reports Pub Date : 2023-10-08 DOI:10.54038/ms.v3i4.51

William Ferreira Alves, Marcelo Castanheira da Silva, Rogério De Freitas Lacerda, Anselmo Fortunato Ruiz Rodriguez, Bráulio Soares Archanjo

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Abstract

Vegetable oils are natural products that are in liquid form, volatile, and aromatic, extracted from different parts of plants. In the Amazon region, vegetable oils are traded and sold by the community to increase their family income. Polymeric nanocapsules are nanoparticles composed of an encapsulating agent (biodegradable polymers) such as polycaprolactone, poly(methyl methacrylate), and creatine, which enclose lipophilic substances (active core). The main technological characteristics of these nanostructured systems are the controlled release of active ingredients, biodisponibility, and chemical and physical stability. In this study, nanocapsules containing copaiba and andiroba vegetable oils, as well as their mixtures, were synthesized. The nanocapsules showed particle sizes, Zeta potentials, and polydispersity indices (PDI) ranging from 117 to 218 nm, 28.5 to 35 mV, and 0.130 to 0.251, respectively. The 30/70 ratio (Copaiba/Andiroba) exhibited the most stable mixture among them.

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含有COPAÍBA (Copaifera spp.)和ANDIROBA (Carapa guianensis Aubl.)的聚合物纳米胶囊的理化分析植物油

植物油是从植物的不同部位提取的液体，具有挥发性和芳香性的天然产物。在亚马逊地区，植物油由社区交易和销售，以增加家庭收入。高分子纳米胶囊是由包封剂(可生物降解聚合物)如聚己内酯、聚(甲基丙烯酸甲酯)和肌酸组成的纳米颗粒，包裹亲脂物质(活性核心)。这些纳米结构系统的主要技术特点是有效成分的可控释放、生物降解性以及化学和物理稳定性。在本研究中，合成了含有copaiba和andiroba植物油的纳米胶囊，以及它们的混合物。纳米胶囊的粒径为117 ~ 218 nm, Zeta电位为28.5 ~ 35 mV, PDI为0.130 ~ 0.251。Copaiba/Andiroba以30/70的比例混合最稳定。

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Multidisciplinary Sciences Reports

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