Sevdalina Lambova, G. Hadzhigeorgiev, G. Gelov, P. Uchilov
{"title":"A case of SAPHO syndrome treated with zoledronic acid and hydroxychloroquine","authors":"Sevdalina Lambova, G. Hadzhigeorgiev, G. Gelov, P. Uchilov","doi":"10.35465/31.2.2023.pp58-66","DOIUrl":null,"url":null,"abstract":"Abstract: SAPHO syndrome is characterized with a set of symptoms including skin lesions, osteoarticular manifestations like aseptic osteitis (of the anterior chest wall or other skeletal sites), peripheral synovitis. Due to the lack of randomized clinical trials and low prevalence of the condition, there are no established treatment guidelines for SAPHO syndrome. Here, we report a clinical case of SAPHO syndrome with osteitis of the sternum and palmoplantar pustulosis successfully treated with zoledronic acid and hydroxychloroquine.","PeriodicalId":38954,"journal":{"name":"Revmatologiia (Bulgaria)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revmatologiia (Bulgaria)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35465/31.2.2023.pp58-66","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: SAPHO syndrome is characterized with a set of symptoms including skin lesions, osteoarticular manifestations like aseptic osteitis (of the anterior chest wall or other skeletal sites), peripheral synovitis. Due to the lack of randomized clinical trials and low prevalence of the condition, there are no established treatment guidelines for SAPHO syndrome. Here, we report a clinical case of SAPHO syndrome with osteitis of the sternum and palmoplantar pustulosis successfully treated with zoledronic acid and hydroxychloroquine.
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