Polymorphism of allelic variants of milk protein genes

Anna Vladimirovna Ilina, Marina Vladimirovna Abramova, Evgeniy Georgievich Evdokimov
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Abstract

The polymorphism of allelic variants of milk productivity genes (alpha-lactoglobulin, beta-casein, kappa-casein, prolactin, somatotropin) in cattle of the yaroslavl breed was studied in conjunction with an assessment of the genetic diversity of the studied population. The distribution of frequencies of occurrence of genotypes in the genes of the studied herds (0.1...0.716049) was determined. Based on the calculations of the average values ??of the genetic diversity indices, the effective number of alleles (1.679...1.994), the Shannon information index (0.594...0.692), the observed heterozygosity (0.087...0.716), the expected heterozygosity (0.404...0.498), fixation index (-0.498...0.823).The coefficient of inbreeding of subpopulations in the studied genes relative to the entire population indicates a weak differentiation of different herds (-0.023 ... -0.002). According to the analysis of the equilibrium distribution of genotypes according to the Hardy-Weinberg law, it is noted that the largest part of the herds has an equilibrium distribution of genotypes. The exception is yaroslavka breeding Plant JSC for the A1A2 beta-casein gene (20.095) and Agromir LLC (Mikhailovskoe branch) for the beta-casein gene (15.581).
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乳蛋白基因等位变异的多态性研究
通过对雅罗斯拉夫尔牛产乳基因(α -乳球蛋白、β -酪蛋白、kappa-酪蛋白、催乳素、生长激素)等位基因变异的多态性分析,对雅罗斯拉夫尔牛种群遗传多样性进行了分析。测定了各基因型在不同种群基因中的出现频率分布(0.1…0.716049)。基于平均值的计算??遗传多样性指数中,有效等位基因数(1.679 ~ 1.994)、香农信息指数(0.594 ~ 0.692)、观察杂合度(0.087 ~ 0.716)、期望杂合度(0.404 ~ 0.498)、固定度(-0.498 ~ 0.823)。各亚群基因的近交系数相对于整个群体表明不同畜群间分化较弱(-0.023…-0.002)。根据Hardy-Weinberg定律对基因型平衡分布进行分析,发现绝大部分畜群具有基因型平衡分布。例外的是yaroslavka育种厂JSC的A1A2 β -酪蛋白基因(20.095)和Agromir LLC (Mikhailovskoe分支)的β -酪蛋白基因(15.581)。
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