{"title":"Prognostic significance of the diameter of superior rectal vein for locally advanced rectal cancer","authors":"Yafang Hong, Anchuan Li, Runfan Chen, Benhua Xu","doi":"10.2217/crc-2023-0004","DOIUrl":null,"url":null,"abstract":"Aim: To evaluate the association between the diameter of the superior rectal vein (dSRV) and prognosis in patients with locally advanced rectal cancer (LARC). Methods: This study included 420 LARC patients. Kaplan-Meier survival analysis and Cox regression models were used for determining the relationship between superior rectal vein diameter and survival. Results: Patients whose dSRV >3.60 mm had better 3 years disease-free survival (85.50 vs 64.2%, p < 0.001) and overall survival (91.90 vs 82.20%, p = 0.005). The multivariate Cox regression analysis showed that the dSRV was an independent prognostic factor for survival. Conclusion: The dSRV measurement is valuable in predicting the prognosis of patients with LARC, and the prognosis of patients with a smaller dSRV seems to be poor.","PeriodicalId":43638,"journal":{"name":"Colorectal Cancer","volume":" 13","pages":"0"},"PeriodicalIF":2.7000,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Colorectal Cancer","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/crc-2023-0004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: To evaluate the association between the diameter of the superior rectal vein (dSRV) and prognosis in patients with locally advanced rectal cancer (LARC). Methods: This study included 420 LARC patients. Kaplan-Meier survival analysis and Cox regression models were used for determining the relationship between superior rectal vein diameter and survival. Results: Patients whose dSRV >3.60 mm had better 3 years disease-free survival (85.50 vs 64.2%, p < 0.001) and overall survival (91.90 vs 82.20%, p = 0.005). The multivariate Cox regression analysis showed that the dSRV was an independent prognostic factor for survival. Conclusion: The dSRV measurement is valuable in predicting the prognosis of patients with LARC, and the prognosis of patients with a smaller dSRV seems to be poor.
目的:探讨局部晚期直肠癌(LARC)患者直肠上静脉(dSRV)直径与预后的关系。方法:本研究纳入420例LARC患者。采用Kaplan-Meier生存分析和Cox回归模型确定直肠上静脉直径与生存的关系。结果:dSRV >3.60 mm的患者3年无病生存率更高(85.50 vs 64.2%， p <0.001)和总生存率(91.90 vs 82.20%， p = 0.005)。多因素Cox回归分析显示，dSRV是影响生存的独立预后因素。结论:dSRV测量对预测LARC患者的预后有一定的价值，dSRV较小的患者预后较差。
期刊介绍：
Colorectal cancer is a major cause of morbidity and mortality, particularly in the developed world. Risk factors for colorectal cancer are on the rise in many countries; populations are aging, and obesity and diabetes are increasing. National screening programs are helping to detect cancer while it is still curable; however, colorectal cancer remains the third leading cause of cancer deaths in the USA and options are still limited for those with more advanced disease. Consequently, colorectal cancer is a major research priority for government, pharmaceutical companies and non-profit organizations. Research into diagnosis and optimum treatment of the disease is progressing rapidly, with new advances reported every day. Colorectal Cancer presents reviews, analysis and commentary. on all aspects of colorectal cancer.
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