[The effect of Enzaprost-F (PGF2) cervical tablets on the corpus luteum in the human body].

M Farkas, Z Vörös
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引用次数: 0

Abstract

Authors removed dextro-ovary of a patient having 7-9th week of gestation for ovarian cyst during abortion. Preoperative cervical dilation was performed by Enzaprost-F cervical tablet containing 20 mg PGF2 agent. Before and 2, 4 and 6 hours after treatment, serum-progesterone and 17-beta-estradiol level was determined. Drug cervical dilation enabled instrumental termination of pregnancy within 4 hours. Histological finding of yellow body showed initial signs of colloid-cystic degeneration, which was followed by minimal decrease of values of serum-steroid concentrations. Authors presume that change in histological picture of yellow body was caused by effect of cervical tablet containing PGF2 agent.

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Enzaprost-F (PGF2)宫颈片对人体黄体的影响。
作者对妊娠7-9周的患者因卵巢囊肿在流产时切除右卵巢。术前予Enzaprost-F宫颈片,含PGF2剂20 mg。测定治疗前、治疗后2、4、6 h血清孕酮、17-雌二醇水平。药物宫颈扩张使器械终止妊娠在4小时内。黄体的组织学发现显示胶体囊变性的初步迹象,随后血清类固醇浓度值略有下降。作者推测黄体组织学改变是由含PGF2制剂的宫颈片作用所致。
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