Prolonged Honeymoon Period in Type I Diabetes (T1D) Patients on Low-Carbohydrate Diet (LCD)

Michael Wood, Koji Ebe, Hiroshi Bando
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Abstract

The presented case is a 68-year-old female with Type 1 diabetes (T1D). She was admitted for an emergency case with acute distress in January 2018 and was diagnosed with T1D with a blood glucose (BG) level of 459 mg/dL, HbA1c of 13.7%, glutamic acid decarboxylase autoantibody (GADA) level >2000 U/mL (<5 U/mL), and C-reactive protein (CRP) level of 1.10 ng/mL. She received Multiple Daily Injections (MDI) of insulin for 3 months, and then her HbA1c decreased to 7.3%. After that, she has been on a super-low carbohydrate diet (LCD) and received only Lantus XR and ipragliflozin. Serum CRP showed 0.2 ng/mL, suggesting a prolonged honeymoon period for years through continuous LCD.
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低碳水化合物饮食延长1型糖尿病患者蜜月期
本病例为68岁女性1型糖尿病(T1D)患者。患者于2018年1月因急性窘迫急诊入院,诊断为T1D,血糖(BG) 459 mg/dL,糖化血红蛋白(HbA1c) 13.7%,谷氨酸脱羧酶自身抗体(GADA) 2000 U/mL (5 U/mL), c反应蛋白(CRP) 1.10 ng/mL。患者接受MDI胰岛素注射3个月后,HbA1c降至7.3%。在那之后,她一直在进行超低碳水化合物饮食(LCD),只接受了Lantus XR和ipragliflozin。血清CRP为0.2 ng/mL,通过连续LCD提示蜜月期延长数年。
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