首页 > 最新文献

Asploro journal of biomedical and clinical case reports最新文献

英文 中文
An Unusual Case Presentation of Coexistence of Emphysematous Cystitis and Bilateral Emphysematous Pyelonephritis: A Case Report 气肿性膀胱炎与双侧气肿性肾盂肾炎并存的罕见病例:病例报告
Pub Date : 2024-08-09 DOI: 10.36502/2024/asjbccr.6364
Xueming Hu, Yujie Diao, Yiqin Xia
Background: Emphysematous cystitis (EC) and emphysematous pyelonephritis (EPN) are severe emphysematous urinary tract infections with high mortality. Early diagnosis is often missed due to the lack of typical clinical manifestations.Case Presentation: A 64-year-old woman with type 2 diabetes was transferred to the emergency department for cough and expectoration with shortness of breath. A CT scan revealed gas formation in the bilateral renal pelvis, bilateral ureter, and bladder cavity. Urine bacterial cultures showed Escherichia coli and Streptococcus gallolyticus. The patient’s bladder was drained, and she was administered antibiotics, insulin, and a non-invasive ventilator. The gas disappeared completely, and the patient recovered uneventfully.Conclusion: This is the first reported case of Escherichia coli combined with Streptococcus gallolyticus infection in EC and EPN. More attention should be paid to EC and EPN in diabetes patients. Early conservative treatment is effective.
背景:气肿性膀胱炎(EC)和气肿性肾盂肾炎(EPN)是严重的气肿性尿路感染,死亡率很高。由于缺乏典型的临床表现,往往会错过早期诊断:一名患有 2 型糖尿病的 64 岁女性因咳嗽、排痰和气短被转入急诊科。CT 扫描显示双侧肾盂、双侧输尿管和膀胱腔内有气体形成。尿液细菌培养显示有大肠杆菌和溶胆链球菌。患者的膀胱被引流,并接受了抗生素、胰岛素和无创呼吸机治疗。气体完全消失,患者顺利康复:这是首例大肠埃希菌合并胆溶血性链球菌感染 EC 和 EPN 的病例。糖尿病患者的 EC 和 EPN 应得到更多关注。早期保守治疗是有效的。
{"title":"An Unusual Case Presentation of Coexistence of Emphysematous Cystitis and Bilateral Emphysematous Pyelonephritis: A Case Report","authors":"Xueming Hu, Yujie Diao, Yiqin Xia","doi":"10.36502/2024/asjbccr.6364","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6364","url":null,"abstract":"Background: Emphysematous cystitis (EC) and emphysematous pyelonephritis (EPN) are severe emphysematous urinary tract infections with high mortality. Early diagnosis is often missed due to the lack of typical clinical manifestations.\u0000Case Presentation: A 64-year-old woman with type 2 diabetes was transferred to the emergency department for cough and expectoration with shortness of breath. A CT scan revealed gas formation in the bilateral renal pelvis, bilateral ureter, and bladder cavity. Urine bacterial cultures showed Escherichia coli and Streptococcus gallolyticus. The patient’s bladder was drained, and she was administered antibiotics, insulin, and a non-invasive ventilator. The gas disappeared completely, and the patient recovered uneventfully.\u0000Conclusion: This is the first reported case of Escherichia coli combined with Streptococcus gallolyticus infection in EC and EPN. More attention should be paid to EC and EPN in diabetes patients. Early conservative treatment is effective.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141923903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report: Abnormal Movements of the Tongue Years after Tonsillar Cancer Treatment 病例报告:扁桃体癌治疗多年后舌头活动异常
Pub Date : 2024-07-26 DOI: 10.36502/2024/asjbccr.6360
Sahibjot Bhatia, Nimrit Gahoonia, Kartik Goswami, Pegah Yakhchalian, Richard Pantera
This case describes a 52-year-old female who presented with abnormal movements of the left side of her tongue. The patient was diagnosed with radiation induced myokymia of the tongue. This diagnosis was established based on history and exam findings, while also ruling out the original concern of recurrence of her tonsillar cancer using MRI imaging. The standard for diagnosing myokymia is through the use of electromyographic studies, however this study was not possible with the resources at the hospital.
本病例描述的是一名 52 岁的女性,她的舌头左侧出现异常运动。患者被诊断为辐射诱发的舌肌症。这一诊断是根据病史和检查结果确定的,同时还通过核磁共振成像排除了原来担心的扁桃体癌复发的可能性。诊断肌肌萎缩症的标准是使用肌电图研究,但以医院的资源无法进行这项研究。
{"title":"Case Report: Abnormal Movements of the Tongue Years after Tonsillar Cancer Treatment","authors":"Sahibjot Bhatia, Nimrit Gahoonia, Kartik Goswami, Pegah Yakhchalian, Richard Pantera","doi":"10.36502/2024/asjbccr.6360","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6360","url":null,"abstract":"This case describes a 52-year-old female who presented with abnormal movements of the left side of her tongue. The patient was diagnosed with radiation induced myokymia of the tongue. This diagnosis was established based on history and exam findings, while also ruling out the original concern of recurrence of her tonsillar cancer using MRI imaging. The standard for diagnosing myokymia is through the use of electromyographic studies, however this study was not possible with the resources at the hospital.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141801338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Influencing Factors for Chronic Low Back Pain with Cognitive Impairment 慢性腰背痛伴认知障碍的影响因素分析
Pub Date : 2024-07-09 DOI: 10.36502/2024/asjbccr.6358
Ying Su
Background: Cognitive impairment (CI) is a common complication in chronic low back pain (CLBP) patients, and its progression increases the risk of dementia. However, there is currently a lack of predictive indicators for CLBP-CI. Previous studies have shown that routine blood indexes have predictive value for Alzheimer’s disease, but their relationship with CLBP-CI remains unclear. This study aims to explore the correlation between routine blood indexes and provide evidence of disparities in chronic pain and cognitive impairment between two groups of individuals with low back pain, as well as establish the foundation for longitudinal experimental studies aimed at developing effective interventions for cognitive impairment in individuals with chronic low back pain.Methods: This cross-sectional study was conducted at West China Hospital, Sichuan University. The Montreal Cognitive Assessment (MoCA) was conducted to divide patients into the CLBP-CI or CLBP-nCI group. Statistical analysis was performed to examine the differences between chronic low back pain patients with cognitive impairment and those without cognitive impairment. All statistical tests were conducted at a significance level of α=0.05 for two-sided testing.Results: The prevalence of chronic low back pain with cognitive impairment in this study demonstrates age-related disparities, with a higher prevalence observed among older individuals (P=0.009). A statistically significant difference in white blood cell count was observed between individuals with chronic low back pain and cognitive impairment (P=0.004).Conclusion: Age and white blood cell count may serve as influential factors in the development of chronic low back pain with cognitive impairment. This finding can aid healthcare professionals in implementing early intervention and treatment for individuals experiencing this condition.
背景:认知障碍(CI)是慢性腰背痛(CLBP)患者常见的并发症,其发展会增加痴呆症的风险。然而,目前尚缺乏慢性腰背痛-认知障碍的预测指标。以往的研究表明,血常规指标对阿尔茨海默病具有预测价值,但它们与 CLBP-CI 的关系仍不明确。本研究旨在探讨血常规指标之间的相关性,为两组腰背痛患者在慢性疼痛和认知障碍方面的差异提供证据,并为旨在开发有效干预慢性腰背痛患者认知障碍的纵向实验研究奠定基础:这项横断面研究在四川大学华西医院进行。方法:这项横断面研究在四川大学华西医院进行,通过蒙特利尔认知评估(MoCA)将患者分为CLBP-CI组和CLBP-nCI组。对有认知障碍和无认知障碍的慢性腰背痛患者之间的差异进行了统计分析。所有统计检验均以α=0.05的显著性水平进行双侧检验:结果:在本研究中,伴有认知障碍的慢性腰背痛患者的患病率显示出与年龄相关的差异,老年人的患病率更高(P=0.009)。慢性腰背痛和认知障碍患者的白细胞计数差异有统计学意义(P=0.004):结论:年龄和白细胞计数可能是慢性腰背痛合并认知障碍的影响因素。结论:年龄和白细胞计数可能是慢性腰背痛伴认知障碍发病的影响因素,这一发现有助于医护人员对该病症患者实施早期干预和治疗。
{"title":"Analysis of Influencing Factors for Chronic Low Back Pain with Cognitive Impairment","authors":"Ying Su","doi":"10.36502/2024/asjbccr.6358","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6358","url":null,"abstract":"Background: Cognitive impairment (CI) is a common complication in chronic low back pain (CLBP) patients, and its progression increases the risk of dementia. However, there is currently a lack of predictive indicators for CLBP-CI. Previous studies have shown that routine blood indexes have predictive value for Alzheimer’s disease, but their relationship with CLBP-CI remains unclear. This study aims to explore the correlation between routine blood indexes and provide evidence of disparities in chronic pain and cognitive impairment between two groups of individuals with low back pain, as well as establish the foundation for longitudinal experimental studies aimed at developing effective interventions for cognitive impairment in individuals with chronic low back pain.\u0000Methods: This cross-sectional study was conducted at West China Hospital, Sichuan University. The Montreal Cognitive Assessment (MoCA) was conducted to divide patients into the CLBP-CI or CLBP-nCI group. Statistical analysis was performed to examine the differences between chronic low back pain patients with cognitive impairment and those without cognitive impairment. All statistical tests were conducted at a significance level of α=0.05 for two-sided testing.\u0000Results: The prevalence of chronic low back pain with cognitive impairment in this study demonstrates age-related disparities, with a higher prevalence observed among older individuals (P=0.009). A statistically significant difference in white blood cell count was observed between individuals with chronic low back pain and cognitive impairment (P=0.004).\u0000Conclusion: Age and white blood cell count may serve as influential factors in the development of chronic low back pain with cognitive impairment. This finding can aid healthcare professionals in implementing early intervention and treatment for individuals experiencing this condition.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Successful Endotracheal Intubation of a Patient with Ankylosing Spondylitis: A Case Report 成功为一名强直性脊柱炎患者进行气管插管:病例报告
Pub Date : 2024-07-09 DOI: 10.36502/2024/asjbccr.6359
Hong Tu
Background: Ankylosing spondylitis (AS) is a chronic inflammatory disorder that primarily affects the spine and eventually causes its malformation. Surgery is a common treatment for AS patients. Patients with severe AS usually have difficulty with ventilation or intubation. Therefore, airway management should be carefully evaluated, especially in patients with severe cervical deformities. Anesthesiologists must fully and carefully evaluate the airway in these patients.Case Presentation: A 49-year-old woman with AS suffered from a severe spinal deformity that required surgical treatment under general anesthesia. The patient was monitored for vital signs and adequately oxygenated. Lidocaine was used for cricothyroid puncture and throat anesthesia. The feasibility of tracheal intubation was assessed using a visual laryngoscope to expose the glottis under full surface anesthesia. Finally, a #7 enhanced tracheal catheter was successfully inserted after conventional sequential induction. The surgery was successfully completed, and the patient was discharged 10 days after surgery.Conclusions: Anesthesiologists should fully and carefully assess the presence of a difficult airway in patients with AS, whether it is difficult to ventilate or intubate. Adequate preparation plans are essential.
背景:强直性脊柱炎(AS)是一种主要影响脊柱并最终导致脊柱畸形的慢性炎症性疾病。手术是强直性脊柱炎患者的常见治疗方法。严重强直性脊柱炎患者通常在通气或插管方面存在困难。因此,应仔细评估气道管理,尤其是严重颈椎畸形的患者。麻醉医生必须全面、仔细地评估这些患者的气道情况:一名患有强直性脊柱炎的 49 岁女性患有严重的脊柱畸形,需要在全身麻醉下进行手术治疗。患者接受了生命体征监测和充分吸氧。环甲膜穿刺和喉部麻醉使用了利多卡因。在完全表面麻醉的情况下,使用可视喉镜暴露声门,评估气管插管的可行性。最后,在常规顺序诱导后成功插入了 7 号增强型气管导管。手术顺利完成,患者术后 10 天出院:麻醉医师应全面、仔细地评估强直性脊柱炎患者是否存在困难气道,无论是通气困难还是插管困难。充分的准备计划至关重要。
{"title":"A Successful Endotracheal Intubation of a Patient with Ankylosing Spondylitis: A Case Report","authors":"Hong Tu","doi":"10.36502/2024/asjbccr.6359","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6359","url":null,"abstract":"Background: Ankylosing spondylitis (AS) is a chronic inflammatory disorder that primarily affects the spine and eventually causes its malformation. Surgery is a common treatment for AS patients. Patients with severe AS usually have difficulty with ventilation or intubation. Therefore, airway management should be carefully evaluated, especially in patients with severe cervical deformities. Anesthesiologists must fully and carefully evaluate the airway in these patients.\u0000Case Presentation: A 49-year-old woman with AS suffered from a severe spinal deformity that required surgical treatment under general anesthesia. The patient was monitored for vital signs and adequately oxygenated. Lidocaine was used for cricothyroid puncture and throat anesthesia. The feasibility of tracheal intubation was assessed using a visual laryngoscope to expose the glottis under full surface anesthesia. Finally, a #7 enhanced tracheal catheter was successfully inserted after conventional sequential induction. The surgery was successfully completed, and the patient was discharged 10 days after surgery.\u0000Conclusions: Anesthesiologists should fully and carefully assess the presence of a difficult airway in patients with AS, whether it is difficult to ventilate or intubate. Adequate preparation plans are essential.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Latest Topics Concerning Cognitive Impairment Related with Olive Oil, Fruits, Vegetables and Others 与橄榄油、水果、蔬菜及其他有关的认知障碍的最新话题
Pub Date : 2024-07-06 DOI: 10.36502/2024/asjbccr.6357
M. Bando, Hirohisa Urasaki, Hiroshi Bando
The authors focused on nutritional therapy, including low carbohydrate diets (LCD), calorie restriction (CR), lipids, olive oil, and other dietary studies. Recent topics on cognitive impairment related to olive oil, fruits, vegetables, and other factors were described with perspectives. A reverse relationship was observed between total fruit/vegetable intake and dementia risk in the elderly. In a study of 92,383 cases, an intake of more than 7g/day of olive oil showed a 28% decreased risk of dementia-related death. Dietary patterns may influence cognitive mechanisms. Among 8,692 elderly participants, lower odds ratios (OR) for cognitive impairment were found for a protein-enriched diet (PED) at 0.910 and an anti-inflammatory diet (AID) at 0.789.
作者重点介绍了营养疗法,包括低碳水化合物饮食 (LCD)、卡路里限制 (CR)、血脂、橄榄油和其他饮食研究。作者从多个角度阐述了与橄榄油、水果、蔬菜和其他因素有关的认知障碍方面的最新课题。研究发现,水果/蔬菜总摄入量与老年人痴呆症风险之间存在反向关系。在一项针对 92,383 个病例的研究中,每天摄入超过 7 克橄榄油的人患痴呆症相关死亡的风险降低了 28%。饮食模式可能会影响认知机制。在 8,692 名老年参与者中,发现富含蛋白质饮食(PED)的认知障碍几率比(OR)较低,为 0.910,而抗炎饮食(AID)的认知障碍几率比(OR)较低,为 0.789。
{"title":"Latest Topics Concerning Cognitive Impairment Related with Olive Oil, Fruits, Vegetables and Others","authors":"M. Bando, Hirohisa Urasaki, Hiroshi Bando","doi":"10.36502/2024/asjbccr.6357","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6357","url":null,"abstract":"The authors focused on nutritional therapy, including low carbohydrate diets (LCD), calorie restriction (CR), lipids, olive oil, and other dietary studies. Recent topics on cognitive impairment related to olive oil, fruits, vegetables, and other factors were described with perspectives. A reverse relationship was observed between total fruit/vegetable intake and dementia risk in the elderly. In a study of 92,383 cases, an intake of more than 7g/day of olive oil showed a 28% decreased risk of dementia-related death. Dietary patterns may influence cognitive mechanisms. Among 8,692 elderly participants, lower odds ratios (OR) for cognitive impairment were found for a protein-enriched diet (PED) at 0.910 and an anti-inflammatory diet (AID) at 0.789.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141836889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Hepatic and Renal Functions during Intraoperative Sedation with Remimazolam in Elderly Patients under Intrathecal Anesthesia 使用雷马唑仑对鞘内麻醉的老年患者进行术中镇静时的肝功能和肾功能比较
Pub Date : 2024-06-05 DOI: 10.36502/2024/asjbccr.6349
Tang-yuan-meng Zhao
Background: Remimazolam mesylate for injection (RM) is a new benzodiazepine sedative drug. The aim of this trial was to evaluate the effects of drug metabolism on patients’ hepatic and renal functions by comparing liver and renal function laboratory tests 24 hours before and 24 hours after surgery when using Remimazolam mesylate for injection (RM) for intraoperative sedation.Methods: 40 surgical patients who underwent prostate electrocision under elective intrathecal anesthesia were included in this trial. Changes in the patients’ perioperative hepatic and renal function indexes were analyzed using paired t-tests to assess the safety of Remimazolam mesylate for injection (RM) used for sedation in elderly patients under intrathecal anesthesia.Results: The patients’ preoperative 24-hour ALT (u/L) was 18.10 ± 4.97; the postoperative 24-hour ALT (u/L) was 18.08 ± 5.72; P = 0.975.The preoperative 24-hour AST (u/L) was 18.83 ± 4.89; the postoperative 24-hour AST (u/L) was 19.73 ± 4.91; P = 0.358.The preoperative 24-hour TBil (μmol/L) was 10.34 ± 6.16; the postoperative 24-hour TBil (μmol/L) was 12.03 ± 5.25; P = 0.008.The preoperative 24-hour sCr (μmol/L) was 79.43 ± 26.31; the postoperative 24-hour sCr (μmol/L) was 71.80 ± 22.93; P = 0.001.The preoperative 24-hour BUN (mmol/L) was 5.85 ± 1.75; the postoperative 24-hour BUN (mmol/L) was 4.83 ± 1.71; P < 0.001.The preoperative 24-hour GFR (ml/min) was 82.73 ± 29.88; the postoperative 24-hour GFR (ml/min) was 125.23 ± 60.02; P < 0.001.Important vital signs of the patients during the trial were stable, and laboratory tests of liver and renal function showed no abnormal changes of clinical significance.Conclusion: The intraoperative vital signs of the patients were stable, and no significant adverse reactions were observed in liver and kidney functions when Remimazolam mesylate for injection (RM) was used for intrathecal anesthesia-assisted sedation in elderly patients.
背景:注射用甲磺酸雷马唑仑(RM)是一种新型苯二氮卓类镇静药物。本试验旨在通过比较使用注射用甲磺酸雷马唑仑(RM)进行术中镇静时,手术前 24 小时和手术后 24 小时的肝肾功能实验室检查,评估药物代谢对患者肝肾功能的影响。采用配对 t 检验分析患者围手术期肝、肾功能指标的变化,以评估注射用甲磺酸雷马唑仑(RM)用于老年鞘内麻醉镇静的安全性:患者术前24小时ALT(u/L)为(18.10±4.97);术后24小时ALT(u/L)为(18.08±5.72);P=0.975.患者术前24小时AST(u/L)为(18.83±4.89);术后24小时AST(u/L)为(19.73±4.91);P=0.358.术前 24 小时 TBil(μmol/L)为 10.34 ± 6.16;术后 24 小时 TBil(μmol/L)为 12.03 ± 5.25;P = 0.008.术前 24 小时 sCr(μmol/L)为 79.43 ± 26.31;术后 24 小时 sCr(μmol/L)为 71.80±22.93;P = 0.001.术前24小时BUN(mmol/L)为5.85±1.75;术后24小时BUN(mmol/L)为4.83±1.71;P < 0.001.术前24小时GFR(ml/min)为82.73±29.88;术后24小时GFR(ml/min)为125.23±60.02;P<0.001.试验期间患者重要生命体征平稳,肝肾功能实验室检查无临床意义的异常变化:结论:注射用甲磺酸雷马唑仑(RM)用于老年患者鞘内麻醉辅助镇静时,患者术中生命体征平稳,肝肾功能未见明显不良反应。
{"title":"Comparison of Hepatic and Renal Functions during Intraoperative Sedation with Remimazolam in Elderly Patients under Intrathecal Anesthesia","authors":"Tang-yuan-meng Zhao","doi":"10.36502/2024/asjbccr.6349","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6349","url":null,"abstract":"Background: Remimazolam mesylate for injection (RM) is a new benzodiazepine sedative drug. The aim of this trial was to evaluate the effects of drug metabolism on patients’ hepatic and renal functions by comparing liver and renal function laboratory tests 24 hours before and 24 hours after surgery when using Remimazolam mesylate for injection (RM) for intraoperative sedation.\u0000Methods: 40 surgical patients who underwent prostate electrocision under elective intrathecal anesthesia were included in this trial. Changes in the patients’ perioperative hepatic and renal function indexes were analyzed using paired t-tests to assess the safety of Remimazolam mesylate for injection (RM) used for sedation in elderly patients under intrathecal anesthesia.\u0000Results: The patients’ preoperative 24-hour ALT (u/L) was 18.10 ± 4.97; the postoperative 24-hour ALT (u/L) was 18.08 ± 5.72; P = 0.975.\u0000The preoperative 24-hour AST (u/L) was 18.83 ± 4.89; the postoperative 24-hour AST (u/L) was 19.73 ± 4.91; P = 0.358.\u0000The preoperative 24-hour TBil (μmol/L) was 10.34 ± 6.16; the postoperative 24-hour TBil (μmol/L) was 12.03 ± 5.25; P = 0.008.\u0000The preoperative 24-hour sCr (μmol/L) was 79.43 ± 26.31; the postoperative 24-hour sCr (μmol/L) was 71.80 ± 22.93; P = 0.001.\u0000The preoperative 24-hour BUN (mmol/L) was 5.85 ± 1.75; the postoperative 24-hour BUN (mmol/L) was 4.83 ± 1.71; P < 0.001.\u0000The preoperative 24-hour GFR (ml/min) was 82.73 ± 29.88; the postoperative 24-hour GFR (ml/min) was 125.23 ± 60.02; P < 0.001.\u0000Important vital signs of the patients during the trial were stable, and laboratory tests of liver and renal function showed no abnormal changes of clinical significance.\u0000Conclusion: The intraoperative vital signs of the patients were stable, and no significant adverse reactions were observed in liver and kidney functions when Remimazolam mesylate for injection (RM) was used for intrathecal anesthesia-assisted sedation in elderly patients.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141386172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anesthetic Management of a Child with Severe Intestinal Obstruction 严重肠梗阻患儿的麻醉管理
Pub Date : 2024-06-05 DOI: 10.36502/2024/asjbccr.6350
Yun Ma
A 4-year-old child was diagnosed with intestinal obstruction and was scheduled to undergo exploratory laparotomy. Anesthesia evaluation, preparation, airway management, and intraoperative circulation maintenance were thoroughly addressed. This case report discusses the key points of anesthesia management in children with intestinal obstruction and provides a reference for the anesthesia management of children with abdominal distension.
一名 4 岁儿童被诊断为肠梗阻,计划接受剖腹探查术。对麻醉评估、准备、气道管理和术中循环维持进行了全面讨论。本病例报告讨论了肠梗阻患儿的麻醉管理要点,为腹胀患儿的麻醉管理提供了参考。
{"title":"Anesthetic Management of a Child with Severe Intestinal Obstruction","authors":"Yun Ma","doi":"10.36502/2024/asjbccr.6350","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6350","url":null,"abstract":"A 4-year-old child was diagnosed with intestinal obstruction and was scheduled to undergo exploratory laparotomy. Anesthesia evaluation, preparation, airway management, and intraoperative circulation maintenance were thoroughly addressed. This case report discusses the key points of anesthesia management in children with intestinal obstruction and provides a reference for the anesthesia management of children with abdominal distension.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141384622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Preoperative Accurate Evaluation and Intervention on Prognosis and Outcome in Elderly Patients with Painless Gastroenteroscopy: Protocol for A Single-Centre Randomized Controlled Trial 术前准确评估和干预对老年无痛胃肠镜检查患者预后和结局的影响:单中心随机对照试验方案
Pub Date : 2024-02-19 DOI: 10.36502/2024/asjbccr.6336
Hongzhou Chen, Rurong Wang
Background: Factors such as abstinence from drinking, fasting, intestinal preparation, and stress responses can contribute to issues like inadequate blood volume, hypoglycemia, and electrolyte imbalances. The ASA classification presently serves as a primary assessment standard globally. In response to prevailing clinical challenges, we propose enhancing the preoperative assessment for elderly patients undergoing painless gastroenteroscopy. This enhancement involves incorporating the Frailty score, bedside ultrasound, and bedside laboratory results alongside the ASA classification, to establish a comprehensive assessment system. This holistic approach aims to monitor patients’ fluid balance, electrolyte levels, and blood glucose changes, facilitating precise interventions and optimized anesthesia strategies. The ultimate goal is to diminish perioperative adverse events, especially those related to the cardiovascular system, thereby enhancing prognosis, outcomes, and patient satisfaction among the elderly.Methods: This study is a randomized controlled trial conducted at a single center. It includes 204 patients scheduled for painless gastroenteroscopy. Eligible subjects will be randomly assigned to either Group A or Group B. Pre-anesthesia assessments will be conducted twice – during the preoperative visit and upon entry to the endoscopy center on the examination day. Evaluation parameters will encompass the Edmonton Frail Scale (EFS), bedside ultrasound measurements including inspiratory IVCDmax, expiratory IVCDmin, and calculation of the inferior vena cava collapse index (IVC-CI). Additionally, serum electrolyte (potassium) and blood glucose levels will be measured. Patients in Group A will receive specific interventions based on predetermined criteria. The primary endpoint is anesthesia-related adverse events. The measurements will be performed perioperatively, post-treatment, and at 1 day, 3 days, and 7 days after the end of treatment.
背景:禁酒、禁食、肠道准备和应激反应等因素会导致血容量不足、低血糖和电解质失衡等问题。目前,ASA 分类是全球的主要评估标准。为了应对当前的临床挑战,我们建议加强对接受无痛胃肠镜检查的老年患者的术前评估。这一改进包括将虚弱评分、床旁超声检查和床旁实验室结果与 ASA 分级相结合,以建立一个全面的评估系统。这种综合方法旨在监测患者的体液平衡、电解质水平和血糖变化,以便进行精确干预和优化麻醉策略。最终目的是减少围术期不良事件,尤其是与心血管系统相关的不良事件,从而提高老年人的预后、疗效和患者满意度:本研究是在一个中心进行的随机对照试验。方法:这项研究是在一个中心进行的随机对照试验,包括204名计划接受无痛胃肠镜检查的患者。符合条件的受试者将被随机分配到 A 组或 B 组。麻醉前评估将进行两次--术前就诊时和检查当天进入内镜中心时。评估参数将包括埃德蒙顿虚弱量表(EFS)、床旁超声测量(包括吸气IVCDmax、呼气IVCDmin)和下腔静脉塌陷指数(IVC-CI)计算。此外,还将测量血清电解质(钾)和血糖水平。A 组患者将根据预定标准接受特定干预。主要终点是麻醉相关不良事件。测量将在围手术期、治疗后以及治疗结束后 1 天、3 天和 7 天进行。
{"title":"Effect of Preoperative Accurate Evaluation and Intervention on Prognosis and Outcome in Elderly Patients with Painless Gastroenteroscopy: Protocol for A Single-Centre Randomized Controlled Trial","authors":"Hongzhou Chen, Rurong Wang","doi":"10.36502/2024/asjbccr.6336","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6336","url":null,"abstract":"Background: Factors such as abstinence from drinking, fasting, intestinal preparation, and stress responses can contribute to issues like inadequate blood volume, hypoglycemia, and electrolyte imbalances. The ASA classification presently serves as a primary assessment standard globally. In response to prevailing clinical challenges, we propose enhancing the preoperative assessment for elderly patients undergoing painless gastroenteroscopy. This enhancement involves incorporating the Frailty score, bedside ultrasound, and bedside laboratory results alongside the ASA classification, to establish a comprehensive assessment system. This holistic approach aims to monitor patients’ fluid balance, electrolyte levels, and blood glucose changes, facilitating precise interventions and optimized anesthesia strategies. The ultimate goal is to diminish perioperative adverse events, especially those related to the cardiovascular system, thereby enhancing prognosis, outcomes, and patient satisfaction among the elderly.\u0000Methods: This study is a randomized controlled trial conducted at a single center. It includes 204 patients scheduled for painless gastroenteroscopy. Eligible subjects will be randomly assigned to either Group A or Group B. Pre-anesthesia assessments will be conducted twice – during the preoperative visit and upon entry to the endoscopy center on the examination day. Evaluation parameters will encompass the Edmonton Frail Scale (EFS), bedside ultrasound measurements including inspiratory IVCDmax, expiratory IVCDmin, and calculation of the inferior vena cava collapse index (IVC-CI). Additionally, serum electrolyte (potassium) and blood glucose levels will be measured. Patients in Group A will receive specific interventions based on predetermined criteria. The primary endpoint is anesthesia-related adverse events. The measurements will be performed perioperatively, post-treatment, and at 1 day, 3 days, and 7 days after the end of treatment.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140451566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Gastric Contents Reflux Aspiration during General Anesthesia Induction in A Patient with Femoral Vein Atrial Septal Defect Closure 一例股静脉房室隔缺损封堵术患者在全身麻醉诱导过程中发生胃内容物反流吸入的病例
Pub Date : 2024-02-06 DOI: 10.36502/2024/asjbccr.6335
Bo Xu, Rurong Wang
Background: Aspiration of gastric contents during the induction of general anesthesia remains a significant cause of mortality and morbidity in anesthesia. We report an 18-year-old patient with a closed atrial septal defect who developed gastric content reflux aspiration and severe aspiration pneumonia despite abstaining from drinking and fasting for more than 12 hours.Case Presentation: An 18-year-old female patient with congenital heart disease (atrial septal defect) had no previous history of gastroesophageal reflux. After fully abstaining from drinking and fasting (more than 12h), conventional anesthesia was induced, and after the patient’s spontaneous breathing and consciousness disappeared, the patient was assisted with mandibular support with both hands and mask pressure. The induction process was smooth. When preparing for intubation, a large amount of yellow fluid was found in the patient’s mouth. Intubation was performed immediately after suction. Aspiration pneumonia still occurs after the operation even if the patient is treated promptly.Conclusions: As the incidence of perioperative pulmonary aspiration is relatively low, precautions to prevent aspiration tend to be overlooked. We should be alert to the complications of gastric contents regurgitation aspiration in patients with sufficient abstention and fasting during general anesthesia intubation.
背景:在全身麻醉诱导过程中吸入胃内容物仍然是导致麻醉死亡和发病的一个重要原因。我们报告了一名 18 岁的闭合性房间隔缺损患者在禁饮和禁食超过 12 小时的情况下发生胃内容物反流吸入和严重吸入性肺炎的病例:一名患有先天性心脏病(房间隔缺损)的 18 岁女性患者既往没有胃食管反流病史。在完全禁饮禁食(超过 12 小时)后,进行常规麻醉诱导,在患者自主呼吸和意识消失后,协助患者双手下颌支撑,面罩加压。诱导过程非常顺利。准备插管时,发现患者口中有大量黄色液体。吸痰后立即进行了插管。结论:结论:由于围手术期肺部吸入的发生率相对较低,预防吸入的措施往往被忽视。结论:由于围术期肺吸入的发生率相对较低,因此预防吸入的注意事项容易被忽视,我们应警惕全身麻醉插管期间充分禁食和禁水患者的胃内容物反流吸入并发症。
{"title":"A Case of Gastric Contents Reflux Aspiration during General Anesthesia Induction in A Patient with Femoral Vein Atrial Septal Defect Closure","authors":"Bo Xu, Rurong Wang","doi":"10.36502/2024/asjbccr.6335","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6335","url":null,"abstract":"Background: Aspiration of gastric contents during the induction of general anesthesia remains a significant cause of mortality and morbidity in anesthesia. We report an 18-year-old patient with a closed atrial septal defect who developed gastric content reflux aspiration and severe aspiration pneumonia despite abstaining from drinking and fasting for more than 12 hours.\u0000Case Presentation: An 18-year-old female patient with congenital heart disease (atrial septal defect) had no previous history of gastroesophageal reflux. After fully abstaining from drinking and fasting (more than 12h), conventional anesthesia was induced, and after the patient’s spontaneous breathing and consciousness disappeared, the patient was assisted with mandibular support with both hands and mask pressure. The induction process was smooth. When preparing for intubation, a large amount of yellow fluid was found in the patient’s mouth. Intubation was performed immediately after suction. Aspiration pneumonia still occurs after the operation even if the patient is treated promptly.\u0000Conclusions: As the incidence of perioperative pulmonary aspiration is relatively low, precautions to prevent aspiration tend to be overlooked. We should be alert to the complications of gastric contents regurgitation aspiration in patients with sufficient abstention and fasting during general anesthesia intubation.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139800720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beneficial Japanese Seasoning Sprinkle (Furikake) Leading to Satisfactory Cuisine and Life 有益的日本调味品洒(Furikake),带来满意的美食和生活
Pub Date : 2024-02-06 DOI: 10.36502/2024/asjbccr.6334
M. Bando, H. Ogawa, Hiroshi Bando
Japanese cuisine revolves around rice as a staple, accompanied by various innovations. Among these, Japanese seasoning sprinkle (furikake) has garnered attention due to its rich history, delightful taste, versatility in cooking applications, clinical nutrition, and research contributions. Furikake is crafted from ingredients such as fish, seaweed, eggs, meat, beans, sesame seeds, fermented soybeans (natto), vegetables, fruits, and others.There are four main types of furikake: dry, soft, freeze-dried, and oil-based. It also plays a role in research, particularly in improving taste abnormalities. In Japanese nursing homes, residents frequently pair furikake with rice, supplying essential trace elements like Fe, Zn, Mg, and Mn, thereby promoting both physical and mental health.
日本料理以米饭为主食,并伴有各种创新。其中,日本调味料洒(furikake)因其悠久的历史、愉悦的口感、烹饪应用的多样性、临床营养和研究贡献而备受关注。毛糯米糍由鱼、海藻、蛋、肉、豆类、芝麻、发酵大豆(纳豆)、蔬菜、水果等配料制成。毛糯米糍主要有四种类型:干糯米糍、软糯米糍、冻干糯米糍和油糯米糍。它还在研究中发挥作用,特别是在改善味觉异常方面。在日本的养老院里,住客们经常将毛竹与米饭搭配食用,以补充人体所需的铁、锌、镁和锰等微量元素,从而促进身心健康。
{"title":"Beneficial Japanese Seasoning Sprinkle (Furikake) Leading to Satisfactory Cuisine and Life","authors":"M. Bando, H. Ogawa, Hiroshi Bando","doi":"10.36502/2024/asjbccr.6334","DOIUrl":"https://doi.org/10.36502/2024/asjbccr.6334","url":null,"abstract":"Japanese cuisine revolves around rice as a staple, accompanied by various innovations. Among these, Japanese seasoning sprinkle (furikake) has garnered attention due to its rich history, delightful taste, versatility in cooking applications, clinical nutrition, and research contributions. Furikake is crafted from ingredients such as fish, seaweed, eggs, meat, beans, sesame seeds, fermented soybeans (natto), vegetables, fruits, and others.\u0000There are four main types of furikake: dry, soft, freeze-dried, and oil-based. It also plays a role in research, particularly in improving taste abnormalities. In Japanese nursing homes, residents frequently pair furikake with rice, supplying essential trace elements like Fe, Zn, Mg, and Mn, thereby promoting both physical and mental health.","PeriodicalId":93523,"journal":{"name":"Asploro journal of biomedical and clinical case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140461168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Asploro journal of biomedical and clinical case reports
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1