Bioactive peptides from mushroom proteins

Adheeti Jain, Rahul V Rathod, Rushikesh Subhash Pharate
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Abstract

Bioactive peptides (BPs) are multifunctional proteins that have a variety of activities and strong pharmacological effects. Due to the food-derived BPs' extensive spectrum of health benefits and numerous bioactivities, including antioxidant, immunological, anti-ageing, and anti-inflammatory activities, research on these compounds has not been interrupted throughout the past few decades. To balance the daily rise in the intake of functional foods and nutraceuticals, it is important to adopt healthy lifestyle choices. As a result, these peptides are crucial in the creation of numerous functional meals. Additionally, studies have demonstrated that peptide treatments are safer from a toxicological standpoint and have fewer adverse effects than small molecule medications. Long recognized for their culinary qualities, mushrooms have been a favourite food of the most important civilizations in history. They are currently the subject of renewed investigation due to their medicinal properties. Mushrooms provide substantial amounts of necessary proteins, dietary nondigestible carbohydrates, unsaturated fats, minerals, and different vitamins. These nutritional advantages have increased mushroom consumption and led to the creation of a variety of processed mushroom products. Bioactive peptides that have been directly or indirectly isolated from mushrooms or their mycelia are known as mushroom bioactive peptides (MBAPs). The advantages of MBAPs for promoting health and preventing disease, including their antihypertensive, antioxidant, and antibacterial actions, are becoming more widely acknowledged. However, this area is still underdeveloped, and there aren't many pertinent reviews. Therefore, the purpose of this study was to outline the current state of MBAP research with a focus on preparatory and biological operations.
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蘑菇蛋白的生物活性肽
生物活性肽是一种具有多种活性和药理作用的多功能蛋白。由于食物来源的bp具有广泛的健康益处和许多生物活性,包括抗氧化、免疫、抗衰老和抗炎活性,在过去的几十年里,对这些化合物的研究一直没有中断。为了平衡每天增加的功能性食物和营养食品的摄入量,选择健康的生活方式很重要。因此,这些肽在许多功能性膳食的创造中至关重要。此外,研究表明,从毒理学的角度来看,肽治疗更安全,副作用也比小分子药物少。长期以来,蘑菇因其烹饪品质而被公认,是历史上最重要的文明最喜欢的食物。由于其药用特性,它们目前正在重新研究。蘑菇提供大量必需的蛋白质、不可消化的碳水化合物、不饱和脂肪、矿物质和不同的维生素。这些营养优势增加了蘑菇的消费量,并导致了各种加工蘑菇产品的产生。从蘑菇及其菌丝体中直接或间接分离的生物活性肽被称为蘑菇生物活性肽(MBAPs)。MBAPs在促进健康和预防疾病方面的优势,包括其抗高血压、抗氧化和抗菌作用,正得到越来越广泛的认可。然而,这一领域还不发达,相关的评论也不多。因此,本研究的目的是概述MBAP研究的现状,重点是准备和生物操作。
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