Ayman Turk, Solip Lee, Hak Hyun Lee, Sang Won Yeon, Se Hwan Ryu, Geum Hee Seo, Hyun You Chang, Bang Yeon Hwang, Mi Kyeong Lee
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引用次数: 0
Abstract
ABSTRACT Morchella fluvialis , a morel mushroom, is one of the most famous edible mushrooms all over the world. Interest in this mushroom is steadily increasing due to its organoleptic properties and nutritional value. The methanolic extract of M. fluvialis showed α-glucosidase inhibitory and antioxidant activities in an assay system. Therefore, the purification and characterisation of bioactive metabolites and evaluation of biological activity were conducted. Fractionation of the M. fluvialis extract resulted in the isolation of nine compounds, namely, three fatty acids, (9 Z ,12 Z )-octadecadienoic acid (linoleic acid, 1), (9 Z ,12 Z )-3-hydroxyoctadecadienoic acid (2) and (6 Z ,9 Z )-13-hydroxyoctadecadienoic acid (3); four sterols, stellasterol (4), ergosterol peroxide (5), ergosterol (6) and brassicasterol (7); one sugar alcohol, arabitol (8); and nicotinamide (9). Among them, compounds 2–3 and 7 were first reported from Morchella . In addition, compound 1 exhibited potent α-glucosidase inhibition, with an IC 50 value of 14.8 μM. The content of compound 1, the major compound, was 1.2 mg · g –1 extract, as quantitated by HPLC analysis, which was lower than the IC 50 value of compound 1. Therefore, M. fluvialis can benefit from diabetes and related diseases through the synergistic effect of linoleic acid (1) and other ingredients.
期刊介绍:
Folia Horticulturae is an international, scientific journal published in English. It covers a broad research spectrum of aspects related to horticultural science that are of interest to a wide scientific community and have an impact on progress in both basic and applied research carried out with the use of horticultural crops and their products. The journal’s aim is to disseminate recent findings and serve as a forum for presenting views as well as for discussing important problems and prospects of modern horticulture, particularly in relation to sustainable production of high yield and quality of horticultural products, including their impact on human health.