Maduramycosis masquerading malignancy: A case report from rural oncology center

Anuradha Shukla, Deepander Singh Rathore, Rahatdeep Brar, Ankur Dwivedi
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Abstract

Mycetoma is a chronic granulomatous inflammation of the dermis and epidermis caused by filamentous bacteria in 60% of cases (actinomycetoma) or fungi (eumycetoma) in 40% of cases. A 45-year-old female presented with a left foot ulcer and gradually increasing swelling for 13 years in our department. The radiograph revealed multiple punch-out lytic areas in the tarsals with sclerosis and destruction of the calcaneum. The characteristic “dotin-circle” sign was appreciated on both ultrasound and magnetic resonance imaging. The causative organism and the radiological evaluation, especially bone involvement, are the most important factors that determine the choice of treatment. In the initial stages, chemotherapeutic drugs along with surgery are effective. The current concept is with treatment with a combination of drugs under the name of Welsh regimen.
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假性恶性马杜罗菌病:农村肿瘤中心1例报告
足菌肿是一种真皮和表皮的慢性肉芽肿性炎症,60%的病例由丝状细菌(放线菌瘤)引起,40%的病例由真菌(真菌瘤)引起。一名45岁女性,因左脚溃疡及逐渐加重的肿胀在我科就诊13年。x线片显示跗骨有多个穿孔溶解区,伴有硬化和跟骨破坏。超声和磁共振成像均发现特征性的“点环”征。致病生物和放射学评估,特别是骨受累,是决定治疗选择的最重要因素。在最初阶段,化疗药物和手术是有效的。目前的概念是以威尔士方案的名义进行药物联合治疗。
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