Type 2 Myocardial Infarction on the Background of Coronary Vasospasm and Invasive Tactics of Its Diagnosis and Treatment

D. Yu. Gamayunov, A. N. Kalyagin, N. M. Balabina, A. V. Sinkov, E. S. Chujko, E. R. Kiseleva, K. B. Gajnutdinov, A. V. Sorzheev, E. O. Bykov
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引用次数: 1

Abstract

Currently, type 2 myocardial infarction is a rather significant problem, both in terms of diagnosis and treatment. Myocardial infarction without obstructive coronary artery damage occurs in 5-10 % of patients with a myocardial infarction. Optimal strategies for the diagnosis and treatment of patients with myocardial damage associated with non-thrombotic mechanisms have not yet been determined. The article describes a clinical observation of type 2 myocardial infarction on the background of vasospasm, as well as diagnostic and therapeutic tactics in this clinical situation. The main provisions: the patient was 22 years old in the cardiology department due to the pain syndrome behind the sternum for the first time in his life and an increase in body temperature to 37.5 C. From anamnesis: active bodybuilding, taking testosterone in injectable form. The electrocardiogram revealed changes in the type of transmural myocardial ischemia without the dynamics characteristic of myocardial infarction. Troponin I (quantitative test) — 2.1 ng/ml at laboratory reference values of 0.010-0.023 ng/ml. A diagnostic search was conducted for myocardial infarction and acute pericarditis. For the purpose of differential diagnosis, coronary angiography was performed, during which dynamic stenosis of the posterior descending artery was revealed. The decision to stent the vessel was not made. Echocardiography revealed areas of local contractility disorders. The data of the examination showed in favor of myocardial infarction without coronary artery obstruction (type 2). Taking into account the absence of occlusive-stenotic lesions of the coronary arteries, the presence of vasospasm, 1 platelet aggregation inhibitor, medium-dose statins, isosorbide dinitrate, calcium channel blocker, angiotensin-converting enzyme inhibitor was prescribed. Conclusion. Invasive tactics made it more likely to diagnose type 2 myocardial infarction and prescribe the most optimal drug therapy.
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冠脉血管痉挛背景下的2型心肌梗死及其有创诊疗策略
目前,无论是在诊断还是治疗方面,2型心肌梗死都是一个相当重要的问题。无阻塞性冠状动脉损伤的心肌梗死发生在心肌梗死患者的5- 10%。诊断和治疗与非血栓形成机制相关的心肌损伤患者的最佳策略尚未确定。本文介绍了以血管痉挛为背景的2型心肌梗死的临床观察,以及在这种临床情况下的诊断和治疗策略。主要规定:患者22岁,首次出现胸骨后疼痛综合征,体温升高至37.5℃,在心内科就诊。从记忆开始:积极健身,注射睾酮。心电图显示跨壁心肌缺血类型改变,无心肌梗死的动力学特征。肌钙蛋白I(定量试验)- 2.1 ng/ml,实验室参考值为0.010-0.023 ng/ml。对心肌梗死和急性心包炎进行了诊断搜索。为鉴别诊断,行冠状动脉造影,造影显示后降支动态狭窄。没有做出血管内支架的决定。超声心动图显示局部收缩性障碍。检查数据显示有利于心肌梗死,无冠状动脉阻塞(2型)。考虑到冠状动脉没有闭塞狭窄病变,存在血管痉挛,处方1血小板聚集抑制剂,中剂量他汀类药物,硝酸异山梨酯,钙通道阻滞剂,血管紧张素转换酶抑制剂。结论。侵入性策略更容易诊断出2型心肌梗死,并开出最佳的药物治疗方案。
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来源期刊
Arhiv
Arhiv" Vnutrennej Mediciny Medicine-General Medicine
CiteScore
0.50
自引率
0.00%
发文量
43
审稿时长
8 weeks
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