Natural Products for the Treatment of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review

IF 2.3 Q3 PHARMACOLOGY & PHARMACY Scientia Pharmaceutica Pub Date : 2023-11-08 DOI:10.3390/scipharm91040053
Saverio Nucera, Rosa Maria Bulotta, Stefano Ruga, Rosamaria Caminiti, Maria Serra, Roberto Bava, Fabio Castagna, Carmine Lupia, Mariangela Marrelli, Filomena Conforti, Giancarlo Statti, Vincenzo Mollace, Ernesto Palma
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Abstract

Plants are an untapped natural resource; their secondary metabolites take part in a variety of pharmacological activities, making them an essential ingredient in the synthesis of novel medications and the source of reserve resources in this process. Hepatitis and liver cancer are two conditions that can result from non-alcoholic fatty liver disease (NAFLD). NAFLD is a condition that now affects a significant section of the global population. There is a need for preventative action on predisposing factors. Due to their effectiveness and few side effects, herbal medications are frequently utilized for the prevention and treatment of NAFLD. This review discusses the pathogenetic processes of NAFLD and the evidence brought to support the potential of botanical species and their derivatives in limiting the causes that predispose to the onset of NAFLD.
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治疗非酒精性脂肪性肝病的天然产物:综述
植物是一种尚未开发的自然资源;它们的次生代谢产物参与多种药理活动,是新药合成的重要成分和储备资源的来源。肝炎和肝癌是由非酒精性脂肪性肝病(NAFLD)引起的两种疾病。NAFLD是一种影响全球很大一部分人口的疾病。有必要对诱发因素采取预防措施。由于其有效性和副作用小,草药经常被用于NAFLD的预防和治疗。这篇综述讨论了NAFLD的发病过程,并提供了证据来支持植物物种及其衍生物在限制NAFLD发病诱因方面的潜力。
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来源期刊
Scientia Pharmaceutica
Scientia Pharmaceutica Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
4.60
自引率
4.00%
发文量
67
审稿时长
10 weeks
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