Porous Bioceramics use Albumin as a Pore-Forming Material

Ahmad Fadli, Komalasari Komalasari, Irdoni Irdoni, Wan Elsa Novtari Adiani
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Abstract

Porous bioceramics have been used in biomedical field, especially for bone implant. To generate pores in bioceramics, pore creating substances are added into the process of making ceramic bodies. The purpose of this study is to make porous bioceramics with tri calcium phosphate (TCP) raw material using albumin with variation in the amount of albumin in the raw material and drying temperature on the physical and chemical properties of TCP. Raw material slurry was made by mixing 7 g of TCP, 2 g of starch and 1.5 g of Darvan 821A with 5 g, 7 g and 9 g of albumin in a beaker glass while stirring at a rate of 150 rpm for 3 hours. The slurry was poured into a mold and heated in an oven at 180°C, 200°C and 220°C for 1 hour. Subsequently the sample was burned at 600˚C for 1 hour, following with sintering at 1.100°C for 2 hours. Bioceramic porosity is greater by increasing the amount of albumin and drying temperature, while the compressive strength decreases. Obtained TCP porosity is in the ranges of 68% -78% and compressive strength 0.14-1.4 MPa.
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多孔生物陶瓷使用白蛋白作为成孔材料
多孔生物陶瓷已广泛应用于生物医学领域,尤其是骨植入材料。为了在生物陶瓷中产生孔隙,在制作陶瓷体的过程中加入了造孔物质。本研究的目的是利用白蛋白制备多孔生物陶瓷,考察原料中白蛋白含量和干燥温度的变化对三磷酸钙(TCP)理化性能的影响。将7 g TCP、2 g淀粉、1.5 g Darvan 821A与5 g、7 g、9 g白蛋白在烧杯中以150转/分的速度搅拌3小时制成原料浆。将浆料倒入模具中,在180℃、200℃和220℃的烤箱中加热1小时。随后,样品在600℃下燃烧1小时,然后在1.100℃下烧结2小时。随着白蛋白用量的增加和干燥温度的升高,生物陶瓷的孔隙率增大,抗压强度降低。获得的TCP孔隙率为68% ~ 78%,抗压强度为0.14 ~ 1.4 MPa。
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