Conventional Remedy to Lou Gehrig’s Disease - Amyotrophic Lateral Sclerosis (ALS): A Rare Clinical Entity

Q4 Pharmacology, Toxicology and Pharmaceutics Journal of Natural Remedies Pub Date : 2023-11-08 DOI:10.18311/jnr/2023/34259
Deepak Gupta, Mayur Shiralkar, Vaishali Chaudhari
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Abstract

Lou Gehrig’s disease, commonly known as amyotrophic lateral sclerosis, is an incredibly rare clinical condition that affects about 5 in 100,000 people annually in India, making it one of the rarest diseases in the entire world. With an average age of 55, this disease typically impacts people between the ages of 40 and 70. Males are more prone to develop the condition. Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder affecting primarily the motor system, but in which extramotor manifestations are increasingly recognized. The loss of upper and lower motor neurons in the motor cortex, the brain stem nuclei and the anterior horn of the spinal cord gives rise to progressive muscle weakness and wasting. Typically, patients report difficulties swallowing or a shift in voice pitch while speaking due to tongue involvement. Initial ALS symptoms can resemble those of other neuromuscular illnesses and are completely non-specific. In this case report, we described a 44-year-old gentleman who has been diagnosed with Amyotrophic Lateral Sclerosis in accordance to an MRI scan describing symptoms like unable to speak, reduced tongue movements, trouble swallowing, excessive salivation, swelling over the tongue and loss of tongue tone for the past three to four months. The present study discusses the clinical presentation, diagnosis, therapeutic regimen and prognosis. Both allopathic and ayurvedic oral medications with local therapeutic regimens like Jivha Pratisarana (Rubbing of dry powder on tongue) and Nasya (nasal drops of medicated oil) were employed in the patient which have satisfactory results enhancing for betterment of lifestyle.
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肌萎缩性侧索硬化症(ALS)的常规治疗:一种罕见的临床实体
Lou Gehrig 's病,俗称肌萎缩性侧索硬化症,是一种非常罕见的临床疾病,每年在印度约有10万人中有5人患病,使其成为全世界最罕见的疾病之一。这种疾病的平均年龄为55岁,通常影响40至70岁的人群。男性更容易患上这种疾病。肌萎缩性侧索硬化症(ALS)是一种主要影响运动系统的神经退行性疾病,但其运动外表现越来越被认识到。运动皮质、脑干核和脊髓前角的上下运动神经元的丧失导致进行性肌肉无力和消瘦。通常情况下,由于舌头受累,患者报告吞咽困难或说话时音高变化。肌萎缩侧索硬化症的初始症状可能类似于其他神经肌肉疾病,并且完全没有特异性。在这个病例报告中,我们描述了一位44岁的男士,他根据MRI扫描被诊断为肌萎缩性侧索硬化症,描述了过去三到四个月的症状,如无法说话,舌头运动减少,吞咽困难,流涎过多,舌头肿胀和舌音丧失。本文讨论了该病的临床表现、诊断、治疗方案及预后。患者采用了对抗疗法和阿育吠陀口服药物和局部治疗方案,如Jivha Pratisarana(在舌头上摩擦干粉)和Nasya(药用油滴鼻液),结果令人满意,有助于改善生活方式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Natural Remedies
Journal of Natural Remedies Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
0.40
自引率
0.00%
发文量
27
期刊介绍: Nature can provide all the remedies, for all. All substances produced by nature can be recognized; all cells talk the same language as we all are from the same mother cell. Journal of Natural Remedies is devoted toward the understandings of all remedies from nature. Journal of Natural Remedies publishes original articles related to utilisation of any natural source for remedy including bioactive natural products. Studies related to the resources, chemistry (including analytical), biological activity, biotechnology and pharmacology (including toxicology) of archaea, bacteria, protistas, fungi, plants, animals, viruses and minerals fall within the journal’s scope.
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