Xanthogranulomatous appendicitis: A medical marvel

Abstract

Xanthogranulomatous inflammation (XGI) is a rare but well- described type of chronic inflammation. It was in the genitourinary tract where it was first reported. Any organ can be involved but the most common sites are kidney followed by the gallbladder. Histologically, it can be characterized by a collection of lipids- laden macrophages along with inflammatory infiltrate, with or without cholesterol clefts. XGI is extremely uncommon in the appendix. Due to its atypical presentation, it is usually detected post- operatively. Sami Akbulut et al. published a comprehensive study in January 2021 and reported only 38 patients worldwide. Here, we present a case of a 20 – year old female who came to the OPD with typical signs of Acute Appendicitis diagnosed histopathologically as Xanthogranulomatous appendicitis