Preoperative continuous positive airway pressure use improves the hospital experience of children undergoing adenotonsillectomy for obstructive sleep apnea

Katrina Zaballa, Geshani Jayasuriya, Karen Waters
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Abstract

Background: Objective of the study was to determine how the preoperative use of continuous positive airway pressure (CPAP) in children diagnosed with obstructive sleep apnea (OSA), and their compliance with the therapy, impact perioperative outcomes of adenotonsillectomy. Methods: A retrospective chart review was conducted on patients diagnosed with OSA on polysomnography, who underwent adenotonsillectomy between 2011-2017. Comparisons were made between patients who were not prescribed CPAP (N-CPAP), prescribed CPAP but non-compliant (NC-CPAP), and those compliant with their CPAP prescription (C-CPAP) therapy. OSA severity was categorized by total apnea-hypopnea index into mild <5, moderate 5-10, and severe >10. Results: A total of 55 of the 162 patients (34%) were recommended CPAP. For those recommended CPAP, 25 were NC-CPAP and 30 C-CPAP. Compared to N-CPAP, NC-CPAP had a 47% reduction in wait time to surgery (p=0.0008) but 59% increase in LOS (p=0.001), while C-CPAP had 24% reduction in wait time (p=0.12) but 34% increase in LOS (p=0.026). Risk for post-operative admission to pediatric intensive care unit (PICU) was highest in NC-CPAP (OR=12 CI 3-44) and increased in C-CPAP (OR=9 CI 2-33). Children with severe OSA had higher frequency of postoperative CPAP use, NC-CPAP 29% and C-CPAP 64% (p≤0.0001). However, use of CPAP did not prevent a requirement for post-operative oxygen. Conclusions: Amongst children prescribed pre-operative CPAP, compliance with therapy had a positive impact on the patient hospital experience following adenotonsillectomy.
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术前持续气道正压通气可改善因阻塞性睡眠呼吸暂停而行腺扁桃体切除术儿童的住院体验
背景:本研究旨在探讨阻塞性睡眠呼吸暂停(OSA)患儿术前使用持续气道正压通气(CPAP)及依从性对腺扁桃体切除术围手术期预后的影响。方法:对2011-2017年接受腺扁桃体切除术的多导睡眠图诊断为OSA的患者进行回顾性图表分析。比较未开CPAP (N-CPAP)、开CPAP但不遵医嘱(NC-CPAP)和遵医嘱(C-CPAP)治疗的患者。根据总呼吸暂停-低通气指数将OSA严重程度分为轻度(lt;5)、中度(5 ~ 10)和重度(gt;10)。结果:162例患者中55例(34%)推荐CPAP。NC-CPAP 25例,C-CPAP 30例。与N-CPAP相比,NC-CPAP手术等待时间减少了47% (p=0.0008),但LOS增加了59% (p=0.001),而C-CPAP手术等待时间减少了24% (p=0.12),但LOS增加了34% (p=0.026)。NC-CPAP患者术后入院儿科重症监护病房(PICU)的风险最高(OR=12 CI 3-44), C-CPAP患者术后入院风险增加(OR=9 CI 2-33)。重度OSA患儿术后使用CPAP的频率较高,NC-CPAP为29%,C-CPAP为64% (p≤0.0001)。然而,CPAP的使用并不能阻止术后对氧气的需求。结论:在接受术前CPAP治疗的儿童中,对治疗的依从性对腺扁桃体切除术后患者的住院经历有积极影响。
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