Tiruhi Gomktsyan, Angelina Khachatryan, Diana Avakyan, Lernik Hunanyan, Roza Shainova, Armen Karapetyan, Emma Ghazaryan, Asya Vorskanyan, Margarita Dovlatyan, Yana Gharibyan, Aleksandr Yengoyan, Vergush Pivazyan
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引用次数: 0
Abstract
Abstract Eco-friendly ultrasound-assisted synthesis of a series of 3- N -substituted 6-((4-(butylamino)-6-(diethylamino)-1,3,5-triazin-2-yl)oxy)pyridazin-3(2 H )-one derivatives and in silico study to predict their biological activities were carried out. Physicochemical and pharmacokinetic properties were obtained. Absorption, distribution, metabolism, excretion and toxicity properties and bioavailability index were calculated. A comparative analysis of structural similarity based on the Tanimoto coefficient was carried out.
期刊介绍：
Green Processing and Synthesis is a bimonthly, peer-reviewed journal that provides up-to-date research both on fundamental as well as applied aspects of innovative green process development and chemical synthesis, giving an appropriate share to industrial views. The contributions are cutting edge, high-impact, authoritative, and provide both pros and cons of potential technologies. Green Processing and Synthesis provides a platform for scientists and engineers, especially chemists and chemical engineers, but is also open for interdisciplinary research from other areas such as physics, materials science, or catalysis.
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