Mathematical Modeling of Breast Cancer Based on the Caputo–Fabrizio Fractal-Fractional Derivative

IF 3.6 2区 数学 Q1 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Fractal and Fractional Pub Date : 2023-11-06 DOI:10.3390/fractalfract7110805
Muhammad Idrees, Abeer S. Alnahdi, Mdi Begum Jeelani
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Abstract

Breast cancer ranks among the most prevalent malignancies affecting the female population and is a prominent contributor to cancer-related mortality. Mathematical modeling is a significant tool that can be employed to comprehend the dynamics of breast cancer progression and dissemination and to formulate novel therapeutic approaches. This paper introduces a mathematical model of breast cancer that utilizes the Caputo–Fabrizio fractal-fractional derivative. The aim is to elucidate and comprehend the intricate dynamics governing breast cancer cells and cytotoxic T lymphocytes in the context of the fractional derivative. The derivative presented herein offers a broader perspective than the conventional derivative, as it incorporates the intricate fractal characteristics inherent in the process of tumor proliferation. The significance of this study lies in its contribution to a novel mathematical model for breast cancer, which incorporates the fractal characteristics of tumor development. The present model possesses the capability to investigate the impacts of diverse treatment strategies on the proliferation of breast cancer, as well as to formulate novel treatment strategies that exhibit enhanced efficacy.
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基于Caputo-Fabrizio分形-分数阶导数的乳腺癌数学建模
乳腺癌是影响女性人口的最普遍的恶性肿瘤之一,也是癌症相关死亡率的主要原因。数学建模是一种重要的工具,可以用来理解乳腺癌进展和传播的动态,并制定新的治疗方法。本文介绍了一种利用Caputo-Fabrizio分形-分数阶导数的乳腺癌数学模型。目的是阐明和理解在分数衍生物的背景下控制乳腺癌细胞和细胞毒性T淋巴细胞的复杂动力学。本文提出的衍生物比传统的衍生物提供了更广阔的视角,因为它包含了肿瘤增殖过程中固有的复杂的分形特征。这项研究的意义在于它为乳腺癌建立了一个新的数学模型,该模型结合了肿瘤发展的分形特征。本模型能够研究不同治疗策略对乳腺癌增殖的影响,并制定出具有增强疗效的新型治疗策略。
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来源期刊
Fractal and Fractional
Fractal and Fractional MATHEMATICS, INTERDISCIPLINARY APPLICATIONS-
CiteScore
4.60
自引率
18.50%
发文量
632
审稿时长
11 weeks
期刊介绍: Fractal and Fractional is an international, scientific, peer-reviewed, open access journal that focuses on the study of fractals and fractional calculus, as well as their applications across various fields of science and engineering. It is published monthly online by MDPI and offers a cutting-edge platform for research papers, reviews, and short notes in this specialized area. The journal, identified by ISSN 2504-3110, encourages scientists to submit their experimental and theoretical findings in great detail, with no limits on the length of manuscripts to ensure reproducibility. A key objective is to facilitate the publication of detailed research, including experimental procedures and calculations. "Fractal and Fractional" also stands out for its unique offerings: it warmly welcomes manuscripts related to research proposals and innovative ideas, and allows for the deposition of electronic files containing detailed calculations and experimental protocols as supplementary material.
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