Paraneoplastic seropositive AQP4-IgG neuromyelitis optica spectrum disorder associated with sigmoid adenocarcinoma

IF 0.2 4区 医学 Q4 CLINICAL NEUROLOGY Neurology Asia Pub Date : 2023-09-01 DOI:10.54029/2023kvu
Sarah Hasnor Abu Hassan, Sumit Kumar Sonu
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引用次数: 0

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing demyelinating and inflammatory disease of the central nervous system, mediated by aquaporin-4 (AQP4)-immunoglobulin G (IgG) autoimmunity. Although NMOSD is most commonly an idiopathic autoimmune condition, it may also occur as a paraneoplastic syndrome in rare instances. Hereby, we report a rare case of a 61-year-old lady with paraneoplastic AQP4-IgG NMOSD associated with adenocarcinoma of sigmoid colon.
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副肿瘤AQP4-IgG血清阳性视神经脊髓炎频谱障碍伴乙状结肠腺癌
视神经脊髓炎谱系障碍(NMOSD)是一种由水通道蛋白-4 (AQP4)-免疫球蛋白G (IgG)自身免疫介导的中枢神经系统复发性脱髓鞘和炎症性疾病。虽然NMOSD最常见的是一种特发性自身免疫性疾病,但在极少数情况下,它也可能作为副肿瘤综合征发生。在此,我们报告一例罕见的61岁女性副肿瘤AQP4-IgG NMOSD合并乙状结肠腺癌。
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来源期刊
Neurology Asia
Neurology Asia CLINICAL NEUROLOGY-
CiteScore
0.30
自引率
0.00%
发文量
76
审稿时长
>0 weeks
期刊介绍: Neurology Asia (ISSN 1823-6138), previously known as Neurological Journal of South East Asia (ISSN 1394-780X), is the official journal of the ASEAN Neurological Association (ASNA), Asian & Oceanian Association of Neurology (AOAN), and the Asian & Oceanian Child Neurology Association. The primary purpose is to publish the results of study and research in neurology, with emphasis to neurological diseases occurring primarily in Asia, aspects of the diseases peculiar to Asia, and practices of neurology in Asia (Asian neurology).
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