Objective: To investigate the association between atherogenic index of plasma (AIP) and stroke. Methods: The 2015 China Health and Retirement Longitudinal Study (CHARLS) survey was used in this study. Logistic regression was adopted to examine the relationship between AIP, calculated as log (TG/HDL), and stroke. Subgroup analysis was used to further explore the associated factors. Restricted cubic spline (RCS) regression was adopted to estimate the non-linear association. Receiver operator characteristic (ROC) analysis was utilized to calculate the cutoff value of AIP. Results: In this study, 13,027 participants aged 45 years above were enrolled. The odds ratios in the fully adjusted logistic model across the quartiles of AIP were 1.00 (reference), 1.09 (95% CI 0.69–1.72), 1.62 (95% CI 1.06–2.49), 1.07 (1.08–2.58), respectively. Non-linear association between AIP and stroke was not found using RCS regression (p for non-linearity > 0.05). The subgroup analyses showed that the association between AIP and stroke varied in different gender, alcohol and cigarette consumption, but the interaction effects were insignificant (all p > 0.05). The cutoff value of AIP was 0.82, and the area under the curve (AUC) was 0.57. Conclusion: Elevated AIP is significantly associated with the increased risk of stroke in the middle- aged and elderly Chinese, indicating that AIP may be a predictive factor for stroke among the Chinese middle-aged and elderly.
目的：研究血浆致动脉粥样硬化指数（AIP）与中风之间的关系：研究血浆致动脉粥样硬化指数（AIP）与中风之间的关系。研究方法本研究采用 2015 年中国健康与退休纵向研究（CHARLS）调查。采用逻辑回归法研究以对数（TG/HDL）计算的 AIP 与脑卒中之间的关系。采用分组分析进一步探讨相关因素。限制立方样条（RCS）回归用于估计非线性关联。利用受体运算特征（ROC）分析计算 AIP 的临界值。研究结果本研究共招募了 13,027 名 45 岁以上的参与者。在完全调整的逻辑模型中，AIP 四分位数的几率分别为 1.00（参考值）、1.09（95% CI 0.69-1.72）、1.62（95% CI 1.06-2.49）、1.07（1.08-2.58）。使用 RCS 回归未发现 AIP 与中风之间存在非线性关联（非线性 p > 0.05）。亚组分析表明，不同性别、饮酒量和吸烟量的 AIP 与中风的关系各不相同，但交互作用不显著（所有 p > 0.05）。AIP 的临界值为 0.82，曲线下面积（AUC）为 0.57。结论AIP 升高与中国中老年人脑卒中风险增加明显相关，表明 AIP 可能是中国中老年人脑卒中的一个预测因素。
{"title":"The association between atherogenic index of plasma and stroke in Chinese middle-aged and elderly population: a national cross-sectional study","authors":"Feifei Xu, Xi Zhong","doi":"10.54029/2023ayw","DOIUrl":"https://doi.org/10.54029/2023ayw","url":null,"abstract":"Objective: To investigate the association between atherogenic index of plasma (AIP) and stroke. Methods: The 2015 China Health and Retirement Longitudinal Study (CHARLS) survey was used in this study. Logistic regression was adopted to examine the relationship between AIP, calculated as log (TG/HDL), and stroke. Subgroup analysis was used to further explore the associated factors. Restricted cubic spline (RCS) regression was adopted to estimate the non-linear association. Receiver operator characteristic (ROC) analysis was utilized to calculate the cutoff value of AIP. Results: In this study, 13,027 participants aged 45 years above were enrolled. The odds ratios in the fully adjusted logistic model across the quartiles of AIP were 1.00 (reference), 1.09 (95% CI 0.69–1.72), 1.62 (95% CI 1.06–2.49), 1.07 (1.08–2.58), respectively. Non-linear association between AIP and stroke was not found using RCS regression (p for non-linearity > 0.05). The subgroup analyses showed that the association between AIP and stroke varied in different gender, alcohol and cigarette consumption, but the interaction effects were insignificant (all p > 0.05). The cutoff value of AIP was 0.82, and the area under the curve (AUC) was 0.57. Conclusion: Elevated AIP is significantly associated with the increased risk of stroke in the middle- aged and elderly Chinese, indicating that AIP may be a predictive factor for stroke among the Chinese middle-aged and elderly.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"5 49","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139194023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Yalçıntepe, Isik Gorker, Leyla Bozatlı, Hazal Sezginer Guler, Drenushe Zhuri, S. Demir, E. Atlı, E. Atlı, D. Eker, H. Gurkan
Intellectual disability can be defined as a significantly below-average general mental function, accompanied by environmental adaptation and behavioural deterioration. Patient files of 87 children with intellectual disability were evaluated in this study. After clinical exclusion criterias, clinical exome sequencing was performed for 25 of 87 intellectual disability cases with a massively parallel targeted sequencing method. Seventeen variants in the genes MBOAT7, KDM5C, TUBB3, MAN1B1, GFAP, CACNA1A, BCOR, LMNA, LBR, ALS2, ENPP1, UBE3A, TRAPPC9, HSPG2, AFF2, NLGN4, and SOX10 were identified in 14 of 25 patients (56%). Seven of the 17 variants (41.1%) were novel in the genes KDM5C, BCOR, UBE3A, TRAPPC9, AFF2, NLGN4, and SOX10. Seven cases (7/25, 28%) had a definite diagnosis of intellectual disability with their pathogenic variants. The high rate of variant detection (56%) in the current study shows that multiple gene analysis plays an essential role in diagnosing the uncertain etiology of intellectual disability. This study also presents seven novel variants, which are first reported.
{"title":"Clinical exome sequencing reveals an important role for clinical diagnosis of intellectual disability with definition of seven novel variants","authors":"S. Yalçıntepe, Isik Gorker, Leyla Bozatlı, Hazal Sezginer Guler, Drenushe Zhuri, S. Demir, E. Atlı, E. Atlı, D. Eker, H. Gurkan","doi":"10.54029/2023rfz","DOIUrl":"https://doi.org/10.54029/2023rfz","url":null,"abstract":"Intellectual disability can be defined as a significantly below-average general mental function, accompanied by environmental adaptation and behavioural deterioration. Patient files of 87 children with intellectual disability were evaluated in this study. After clinical exclusion criterias, clinical exome sequencing was performed for 25 of 87 intellectual disability cases with a massively parallel targeted sequencing method. Seventeen variants in the genes MBOAT7, KDM5C, TUBB3, MAN1B1, GFAP, CACNA1A, BCOR, LMNA, LBR, ALS2, ENPP1, UBE3A, TRAPPC9, HSPG2, AFF2, NLGN4, and SOX10 were identified in 14 of 25 patients (56%). Seven of the 17 variants (41.1%) were novel in the genes KDM5C, BCOR, UBE3A, TRAPPC9, AFF2, NLGN4, and SOX10. Seven cases (7/25, 28%) had a definite diagnosis of intellectual disability with their pathogenic variants. The high rate of variant detection (56%) in the current study shows that multiple gene analysis plays an essential role in diagnosing the uncertain etiology of intellectual disability. This study also presents seven novel variants, which are first reported.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"264 22-25","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139194839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mirror-image dextrocardia is a physiological variant in which the heart is located in a mirror position to the right of the position of the normal human heart. Mirror-image dextrocardia combined with acute large-artery occlusive stroke is extremely rare in clinical practice. We present here a 67-year- old woman with complete blockage in her left middle cerebral artery. The patient also had a mirror- image dextrocardia. In this report, we share our experience in treating the patient using mechanical thrombectomy. During her visit to the emergency department, we performed various tests to understand the patient’s anatomy. Based on the findings, we decided to approach the femoral artery. Using a combination of stent thrombectomy and intermediate catheter aspiration, we successfully restored blood flow to the patient’s left middle cerebral artery.
{"title":"Mechanical thrombectomy for acute left middle cerebral artery occlusion in a patient with mirror- image dextrocardia","authors":"Xianmin Wang, Chao Jiang, Danni Chen, Xiaobo Li","doi":"10.54029/2023fmr","DOIUrl":"https://doi.org/10.54029/2023fmr","url":null,"abstract":"Mirror-image dextrocardia is a physiological variant in which the heart is located in a mirror position to the right of the position of the normal human heart. Mirror-image dextrocardia combined with acute large-artery occlusive stroke is extremely rare in clinical practice. We present here a 67-year- old woman with complete blockage in her left middle cerebral artery. The patient also had a mirror- image dextrocardia. In this report, we share our experience in treating the patient using mechanical thrombectomy. During her visit to the emergency department, we performed various tests to understand the patient’s anatomy. Based on the findings, we decided to approach the femoral artery. Using a combination of stent thrombectomy and intermediate catheter aspiration, we successfully restored blood flow to the patient’s left middle cerebral artery.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"434 8","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139195514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Ağırcan, Murat Cekic, H. Uyanıkoğlu, Tülin Gesoğlu Demir, Ozlem Ethemoglu
Background & Objective: It is important to be aware of hormonal changes in neurological disease in neurology training. We aimed to investigate the most common disorders which resulted in the clinicians from the Department of Gynecology, Obstetrics, and Reproductive Medicine (GORM) to ask for neurology consultation from the Department of Neurology. Methods: All the neurology consultations requested from the Department of GORM between 2015 and 2023 at Harran University Hospital, Sanliurfa, Turkey, were retrospectively evaluated with regard to demographic characteristics, the reason for referral, neurologic diagnoses, and treatment, imaging features. SPSS statistical software version 22 (IBM Inc. NC, USA) was used to perform all statistical analyses. Results: There were 333 patients with a mean age of 32.5 years (range 17-68) seeking consultations; 287 had obstetric problems, and 46 had gynecological issues. In the obstetric group, pre-eclampsia and Posterior Reversible Encephalopathy Syndrome (PRES) were the most frequent final neurological diagnoses, while headache and acute cerebrovascular disease were the most common frequent problems in the gynecological group. The number of consultations rose from 23 in 2015 to 66 in 2022. The predicted rate of final diagnosis of GORM residents was 58%. The neurologist’s contribution has substantial influence on the management of 208 (62%) patients. Conclusion: Neurologists have a significant contribution to the management of GORM inpatients. In neurological training, importance should be given to the effect of hormonal changes on neurological diseases in neurology training.
{"title":"Evaluation of inpatients neurology consultations in the department of gynecology, obstetrics, and reproductive medicine of a tertiary hospital in Turkey","authors":"D. Ağırcan, Murat Cekic, H. Uyanıkoğlu, Tülin Gesoğlu Demir, Ozlem Ethemoglu","doi":"10.54029/2023xzu","DOIUrl":"https://doi.org/10.54029/2023xzu","url":null,"abstract":"Background & Objective: It is important to be aware of hormonal changes in neurological disease in neurology training. We aimed to investigate the most common disorders which resulted in the clinicians from the Department of Gynecology, Obstetrics, and Reproductive Medicine (GORM) to ask for neurology consultation from the Department of Neurology. Methods: All the neurology consultations requested from the Department of GORM between 2015 and 2023 at Harran University Hospital, Sanliurfa, Turkey, were retrospectively evaluated with regard to demographic characteristics, the reason for referral, neurologic diagnoses, and treatment, imaging features. SPSS statistical software version 22 (IBM Inc. NC, USA) was used to perform all statistical analyses. Results: There were 333 patients with a mean age of 32.5 years (range 17-68) seeking consultations; 287 had obstetric problems, and 46 had gynecological issues. In the obstetric group, pre-eclampsia and Posterior Reversible Encephalopathy Syndrome (PRES) were the most frequent final neurological diagnoses, while headache and acute cerebrovascular disease were the most common frequent problems in the gynecological group. The number of consultations rose from 23 in 2015 to 66 in 2022. The predicted rate of final diagnosis of GORM residents was 58%. The neurologist’s contribution has substantial influence on the management of 208 (62%) patients. Conclusion: Neurologists have a significant contribution to the management of GORM inpatients. In neurological training, importance should be given to the effect of hormonal changes on neurological diseases in neurology training.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"12 2","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139189381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Although stroke rehabilitation (SR) is part of post-stroke recovery, patients have limited knowledge on this subject. This study aims to analyze YouTube videos about SR in terms of the information value and quality. Methods: On YouTube.com; the word “SR” was searched in September 6th, 2021. The listed first 100 videos were classified according to count of like, dislike, source of upload, origin of country and contents of SR. Quality, reliability and accuracy of the videos were determined with Global Quality Score (GQS), Journal of American Medical Association (JAMA) benchmark criteria and Modified DISCERN questionnaire, respectively. Results: According to the results of the study, 59 low quality, 28 medium quality, and 13 high-quality videos were determined. Eighty one percent of the videos contained insufficient data. Academic and physician-sourced videos comprised the majority (84.7%) of the high-quality group. A statistically significant result was found between the video sources and the number of views, likes, dislikes, comments, and video duration (p<0.05). A weak positive correlation was found between video durations and GQS (r=0.671), JAMA benchmark criteria (r=0.665), modified DISCERN (r=0.701) scores (p<0.001). Conclusion: Our results showed that most of the YouTube videos on SR have poor quality and insufficient data. High-quality videos have a longer duration and are uploaded by academic and physician video sources. YouTube can be considered an alternative resource besides tele rehabilitation for patients who need SR and whose health care was interrupted during the COVID pandemic. It can be said that higher-quality videos created by health professionals will be more useful for patient education in future.
{"title":"Youtube as a source of information about stroke rehabilitation during the COVID-19 pandemic","authors":"E. Özduran, V. Hancı","doi":"10.54029/2023kif","DOIUrl":"https://doi.org/10.54029/2023kif","url":null,"abstract":"Objective: Although stroke rehabilitation (SR) is part of post-stroke recovery, patients have limited knowledge on this subject. This study aims to analyze YouTube videos about SR in terms of the information value and quality. Methods: On YouTube.com; the word “SR” was searched in September 6th, 2021. The listed first 100 videos were classified according to count of like, dislike, source of upload, origin of country and contents of SR. Quality, reliability and accuracy of the videos were determined with Global Quality Score (GQS), Journal of American Medical Association (JAMA) benchmark criteria and Modified DISCERN questionnaire, respectively. Results: According to the results of the study, 59 low quality, 28 medium quality, and 13 high-quality videos were determined. Eighty one percent of the videos contained insufficient data. Academic and physician-sourced videos comprised the majority (84.7%) of the high-quality group. A statistically significant result was found between the video sources and the number of views, likes, dislikes, comments, and video duration (p<0.05). A weak positive correlation was found between video durations and GQS (r=0.671), JAMA benchmark criteria (r=0.665), modified DISCERN (r=0.701) scores (p<0.001). Conclusion: Our results showed that most of the YouTube videos on SR have poor quality and insufficient data. High-quality videos have a longer duration and are uploaded by academic and physician video sources. YouTube can be considered an alternative resource besides tele rehabilitation for patients who need SR and whose health care was interrupted during the COVID pandemic. It can be said that higher-quality videos created by health professionals will be more useful for patient education in future.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"50 4","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139192525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: To compare the effect of using cold compression before injecting botulinum toxin (BTX) versus not using cold compression, on pain and bleeding at the injection site, efficacy and the quality of life of patients with hemifacial spasm (HFS). Methods: A prospective, randomized, case crossover design was employed. One hundred fifty-nine (159) patients who were diagnosed as having primary HFS with BTX treatment in the botulinum toxin clinic were randomized during the period from May 2017 to November 2017. Patients were divided into two groups – with cold compression and without cold compression before BTX injection and then evaluated for the severity and frequency of HSF using the Jankovic Rating Scale and quality of life questionnaire. Immediate complications after injection such as pain and bleeding were also assessed. Results: Cold compression before BTX injection significantly decreased the severity and frequency of HFS (p<0.001). Pain in cases where cold compression was used before BTX injection was significantly lower than in those cases not receiving cold compression (p<0.001). Satisfaction scores and bleeding were significantly different (p<0.001). Quality of life was significantly improved after treatment with BTX (p<0.001). Conclusion: Cold compression before BTX injection can improve the efficacy of treatment by reducing severity and frequency. This study confirms previous studies that using cold compression before BTX injection results in a good outcome in relation to satisfaction and bleeding. No significant complications were found. Additionally, BTX injection can also improve quality of life in hemifacial spasm patients.
{"title":"Effect of cold compression before botulinum neuro- toxin injection in hemifacial spasm","authors":"Tasanee Tantirittisak, Peamnapatch Dhanachanvisith","doi":"10.54029/2023nkf","DOIUrl":"https://doi.org/10.54029/2023nkf","url":null,"abstract":"Objectives: To compare the effect of using cold compression before injecting botulinum toxin (BTX) versus not using cold compression, on pain and bleeding at the injection site, efficacy and the quality of life of patients with hemifacial spasm (HFS). Methods: A prospective, randomized, case crossover design was employed. One hundred fifty-nine (159) patients who were diagnosed as having primary HFS with BTX treatment in the botulinum toxin clinic were randomized during the period from May 2017 to November 2017. Patients were divided into two groups – with cold compression and without cold compression before BTX injection and then evaluated for the severity and frequency of HSF using the Jankovic Rating Scale and quality of life questionnaire. Immediate complications after injection such as pain and bleeding were also assessed. Results: Cold compression before BTX injection significantly decreased the severity and frequency of HFS (p<0.001). Pain in cases where cold compression was used before BTX injection was significantly lower than in those cases not receiving cold compression (p<0.001). Satisfaction scores and bleeding were significantly different (p<0.001). Quality of life was significantly improved after treatment with BTX (p<0.001). Conclusion: Cold compression before BTX injection can improve the efficacy of treatment by reducing severity and frequency. This study confirms previous studies that using cold compression before BTX injection results in a good outcome in relation to satisfaction and bleeding. No significant complications were found. Additionally, BTX injection can also improve quality of life in hemifacial spasm patients.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"14 7","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139188946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The aim of this study was to investigate YKL-40 in migraine patients during migraine attacks. Methods: In this prospective study, 30 migraine patients with aura (MWA) and 30 migraine patients without aura (MWOA) who presented to the Neurological Outpatient Department of Konya City Hospital during a migraine episode as well as 28 healthy controls were included. According to the manufacturer’s recommendations, serum YKL-40 levels were determined using an ELISA kit (FineTest). Statistical analysis of the data was performed with the IBM SPSS version 20.0 program. Results: The mean gender and age were similar between groups (p>0.05). The serum YKL-40 level was 3575 ± 604.975 pg/ml in the MWA group, 3339 ± 492.689 pg/ml in the MWOA group and 3190 ± 544.018 pg/ml in the control group. YKL-40 levels were significantly higher in MWA than in the control group (p=0.028). YKL-40 levels were similar in the MWA and MWOA groups (p=0.302). No significant difference was found between the group with MWOA and the control group (p=0.915). Conclusion: Although YKL-40 levels are increased in patients with migraine with aura during an attack, comprehensive studies with a larger sample are needed to clarify the relationship between YKL-40 and migraine.
{"title":"Serum YKL-40 (chitinase 3-like protein 1) levels in migraine patients during an attack","authors":"Bahriye Horasanli, Zeynep Caliskan Sak, Aysun Ozsahin, Keziban Ucar Karabulut","doi":"10.54029/2023rxc","DOIUrl":"https://doi.org/10.54029/2023rxc","url":null,"abstract":"Objectives: The aim of this study was to investigate YKL-40 in migraine patients during migraine attacks. Methods: In this prospective study, 30 migraine patients with aura (MWA) and 30 migraine patients without aura (MWOA) who presented to the Neurological Outpatient Department of Konya City Hospital during a migraine episode as well as 28 healthy controls were included. According to the manufacturer’s recommendations, serum YKL-40 levels were determined using an ELISA kit (FineTest). Statistical analysis of the data was performed with the IBM SPSS version 20.0 program. Results: The mean gender and age were similar between groups (p>0.05). The serum YKL-40 level was 3575 ± 604.975 pg/ml in the MWA group, 3339 ± 492.689 pg/ml in the MWOA group and 3190 ± 544.018 pg/ml in the control group. YKL-40 levels were significantly higher in MWA than in the control group (p=0.028). YKL-40 levels were similar in the MWA and MWOA groups (p=0.302). No significant difference was found between the group with MWOA and the control group (p=0.915). Conclusion: Although YKL-40 levels are increased in patients with migraine with aura during an attack, comprehensive studies with a larger sample are needed to clarify the relationship between YKL-40 and migraine.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"63 2","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139188159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ross syndrome is a rare syndrome consisting of areflexia, tonic pupil and segmental anhidrosis. It has been shown to accompany neuropsychiatric diseases such as psychiatric disorders, headache, and epilepsy. We report here a 19-year-old female who was the first case in which cyclic vomiting syndrome plus was shown to accompany Ross syndrome.
{"title":"Cyclic vomiting syndrome plus accompanying Ross syndrome: More than a peripheral autonomic dysfunction","authors":"Gizem Gürsoy, K. Tutkavul, Şirin Yaşar","doi":"10.54029/2023hra","DOIUrl":"https://doi.org/10.54029/2023hra","url":null,"abstract":"Ross syndrome is a rare syndrome consisting of areflexia, tonic pupil and segmental anhidrosis. It has been shown to accompany neuropsychiatric diseases such as psychiatric disorders, headache, and epilepsy. We report here a 19-year-old female who was the first case in which cyclic vomiting syndrome plus was shown to accompany Ross syndrome.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"2015 3","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139192800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parsonage-Turner syndrome (PTS) is one of the rare peripheral neuropathies that causes sudden and severe pain followed by sensory defect, loss of muscle strength and atrophy in the upper extremities. If a patient experiences persistent shoulder pain after COVID-19 vaccination, followed by weakness and sensory changes in the extremity, Parsonage-Turner syndrome should be considered in the differential diagnosis. We report a rare case of PTS that developed after COVID-19 vaccination.
{"title":"Parsonage-Turner syndrome after COVID-19 vaccination: A case report","authors":"Şule Deveci","doi":"10.54029/2023huh","DOIUrl":"https://doi.org/10.54029/2023huh","url":null,"abstract":"Parsonage-Turner syndrome (PTS) is one of the rare peripheral neuropathies that causes sudden and severe pain followed by sensory defect, loss of muscle strength and atrophy in the upper extremities. If a patient experiences persistent shoulder pain after COVID-19 vaccination, followed by weakness and sensory changes in the extremity, Parsonage-Turner syndrome should be considered in the differential diagnosis. We report a rare case of PTS that developed after COVID-19 vaccination.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"189 1-4","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139194466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The association of multiple symmetric lipomatosis (MSL) and mitochondrial disorders is not frequent. We report a male patient with multiple lipomas, hearing loss, progressive limb-girdle muscle weakness, neuropathy and myoclonia. Serum creatinine kinase was mildly elevated. Electromyography revealed sensory axonal polyneuropathy and myopathy with sparse denervation. A muscle biopsy showed ragged-red fibers. Next-generation DNA sequencing revealed a heteroplasmic m.8344A>G mutation in the MT-TK gene. To the best of our knowledge, this is the first patient to be reported from Turkey with a diagnosis of MSL and myoclonic epilepsy with ragged red fibers (MERRF).
{"title":"Multiple symmetric lipomatosis and MERRF: A case from Turkey","authors":"Sezin Alpaydın Baslo, Betül Tekin, Gokcen Gundogdu Unverengil, Mucahid Erdogan, Mahir Yusifov, D. Ataklı","doi":"10.54029/2023npx","DOIUrl":"https://doi.org/10.54029/2023npx","url":null,"abstract":"The association of multiple symmetric lipomatosis (MSL) and mitochondrial disorders is not frequent. We report a male patient with multiple lipomas, hearing loss, progressive limb-girdle muscle weakness, neuropathy and myoclonia. Serum creatinine kinase was mildly elevated. Electromyography revealed sensory axonal polyneuropathy and myopathy with sparse denervation. A muscle biopsy showed ragged-red fibers. Next-generation DNA sequencing revealed a heteroplasmic m.8344A>G mutation in the MT-TK gene. To the best of our knowledge, this is the first patient to be reported from Turkey with a diagnosis of MSL and myoclonic epilepsy with ragged red fibers (MERRF).","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"36 3-4","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139194811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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