Anti-Viral Activities of Probiotics against Viral Gastroenteritis: A Review

Jung-Whan Chon, Hye-Young Youn, Hyeon-Jin Kim, Hyungsuk Oh, Seok-Hyeong Kang, Won-Uk Hwang, Hajeong Jeong, Hyun-Ju Kim, Kun-Ho Seo, Kwang-Young Song
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Abstract

Globally, acute gastroenteritis is responsible for two million pediatric deaths. In particular, viral gastroenteritis is the most common cause of acute diarrhea, and most children aged <5 years are infected at least once. The common symptoms include profuse watery diarrhea, vomiting, abdominal pain, and fever. Viral gastroenteritis is generally caused by rotavirus, norovirus, astrovirus, and adenovirus. Recently, probiotics use has increased rapidly worldwide due to its inhibitory effect against viral gastroenteritis. In addition, probiotics are known to have anti-inflammatory and anti-allergic effects and enhance immunity without any side effects. Therefore, this review focuses on the anti-viral effects of probiotics on viral gastroenteritis. Furthermore, this review would provide basic data that could be used for developing new products that have improved functionality by addition of probiotics to milk and dairy food.
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益生菌对病毒性胃肠炎的抗病毒作用研究进展
在全球范围内,急性胃肠炎导致200万儿童死亡。特别是病毒性肠胃炎是引起急性腹泻最常见的原因,大多数5岁儿童至少感染过一次。常见症状包括大量水样腹泻、呕吐、腹痛和发烧。病毒性胃肠炎一般由轮状病毒、诺如病毒、星状病毒和腺病毒引起。近年来,由于益生菌对病毒性肠胃炎的抑制作用,益生菌的使用在世界范围内迅速增加。此外,益生菌已知具有抗炎和抗过敏作用,并提高免疫力,没有任何副作用。因此,本文就益生菌对病毒性胃肠炎的抗病毒作用作一综述。此外,该综述将为开发通过在牛奶和乳制品中添加益生菌来改善功能的新产品提供基础数据。
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