Recent advances in vulvovaginal Candidiasis research: A narrative review

Abstract

Vulvovaginal Candidiasis (VVC) is a significant public health concern, and current article focuses primarily on understanding this infection's molecular processes. The hosts defence mechanisms and their dysregulation, such as the innate immune response and the genetic susceptibility factors, play a crucial role in determining the susceptibility to VVC. Candida - host interactions in the vaginal environment, including the adhesion mechanisms and the tissue invasion, have been extensively investigated, revealing the intricate strategies employed by Candida spp. to colonize and persist in the human host. Moreover, the virulence factors