Catha edulis (khat) use and demographic correlates of schizophrenia: Case-control study

Abraha Gosh Woldemariam, Gloria Thupayagale-Tshweneagae
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Abstract

Use of Catha edulis is common among people living with schizophrenia. However, as is the case for most developing countries, the association of Catha edulis use and demographic variables to schizophrenia are not fully understood in Ethiopia. The aim of this study was to determine Catha edulis use and demographic correlates of schizophrenia. Retrospective case-control study was conducted on 37 schizophrenia patients and 103 non schizophrenia patients. Data were collected through face-to-face interviews using structured and pretested questionnaire. Associations between variable were determined using Mantel-Haenszel and Fisher's exact test. Odds ratio and 95% confidence interval were calculated to see the strength of association at 0.05 levels of significance. Findings of the present study show that age 18 to 30 years old (OR = 2.6; p = 0.020), being single (OR = 4.25; p = 0.001), unemployment (OR = 3.82; p = 0.001) and Catha edulis usage (OR = 3.89; p = 0.001) were significantly correlated to schizophrenia.

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卡塔叶(阿拉伯茶)的使用与精神分裂症的人口学相关性:病例对照研究
在精神分裂症患者中,使用国茴香很常见。然而,与大多数发展中国家的情况一样,在埃塞俄比亚,人们并不完全了解国茴香的使用和人口统计学变量与精神分裂症的关联。本研究的目的是确定国茶的使用与精神分裂症的人口统计学相关性。研究对 37 名精神分裂症患者和 103 名非精神分裂症患者进行了回顾性病例对照研究。数据是通过预先测试的结构化问卷进行面对面访谈收集的。采用曼特尔-海恩泽尔检验和费雪精确检验确定变量之间的关联。在 0.05 的显著性水平下,通过计算患病率和 95% 的置信区间来了解相关性的强度。本研究结果表明,18 至 30 岁(OR = 2.6;P = 0.020)、单身(OR = 4.25;P = 0.001)、失业(OR = 3.82;P = 0.001)和使用国菝葜(OR = 3.89;P = 0.001)与精神分裂症显著相关。
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