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The simultaneous impact of interventions on optimism and depression: A meta-analysis 干预措施对乐观和抑郁的同时影响:荟萃分析
Pub Date : 2024-07-08 DOI: 10.1002/mhs2.79
Nicola S. Schutte, John M. Malouff

The positive psychology approach to mental-health-related interventions suggests that a dual focus on positive and problematic characteristics is beneficial and that positive and negative characteristics interact. The present study explored the link between optimism and depression outcomes in intervention studies that assessed both optimism and depression outcomes. A meta-analysis examined effect sizes for depression and optimism and links between depression and optimism outcomes. Eighteen studies with a total of 2153 participants were included. Across studies the weighted effect sizes for the impact of interventions on both depression (g = 0.46) and optimism (g = 0.38) were significant. Optimism and depression outcomes were associated with one another (r(17) = 0.58). Meta-regression analyses also indicated linkages between the two outcomes in that the optimism effect sizes moderated depression effect sizes and depression effect sizes moderated optimism effect sizes. The results of the study lend support to a dual focus on positive and problematic characteristics.

对心理健康相关干预采取积极心理学方法表明,对积极特征和问题特征的双重关注是有益的,而且积极特征和消极特征是相互影响的。本研究探讨了同时评估乐观和抑郁结果的干预研究中乐观与抑郁结果之间的联系。荟萃分析检查了抑郁和乐观的效应大小以及抑郁和乐观结果之间的联系。18项研究共纳入了2153名参与者。在所有研究中,干预措施对抑郁(g = 0.46)和乐观(g = 0.38)的影响的加权效应大小都很显著。乐观和抑郁的结果相互关联(r(17) = 0.58)。元回归分析也表明了这两种结果之间的联系,即乐观的效应大小调节抑郁的效应大小,抑郁的效应大小调节乐观的效应大小。研究结果支持对积极特征和问题特征的双重关注。
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引用次数: 0
Social sharing and expressive suppression in major depressive disorder and borderline personality disorder: An experience sampling study 重度抑郁障碍和边缘型人格障碍中的社交分享和表达抑制:经验取样研究
Pub Date : 2024-07-01 DOI: 10.1002/mhs2.77
Martine W. F. T. Verhees, Eva Ceulemans, Laura Sels, Egon Dejonckheere, Marlies Houben, Peter Kuppens

Major depressive disorder (MDD) and borderline personality disorder (BPD) are characterized by disturbed patterns of emotional and interpersonal functioning, which might imply altered use of emotion regulation in interpersonal contexts. In the current study, we examined how individuals with MDD and/or BPD differ from healthy controls in (1) their overall daily life use of expressive suppression and social sharing and (2) their tendency to adjust the use of these strategies to the emotional context (i.e., preceding negative and positive affect). Thirty-four individuals with MDD, 20 individuals with BPD, 19 individuals with comorbid MDD and BPD, and 40 healthy controls participated in a week of experience sampling during which they reported their use of expressive suppression, social sharing, and experienced negative and positive affect. The results indicated that all clinical groups reported more expressive suppression and social sharing in their daily lives than healthy controls. Group differences remained when controlling for differences in mean experienced affect, except for increased suppression for MDD and increased sharing for BPD and comorbid MDD and BPD, which seemed related to these participants' overall higher levels of negative affect. Additionally, associations between within-person fluctuations in negative or positive affect and subsequent strategy use were equally strong for clinical and control participants, indicating that clinical groups did not differentially adjust the use of suppression and sharing to the emotional context. In conclusion, individuals with MDD and/or BPD showed increased use of suppression and sharing in daily life, which might contribute to, or follow from their emotional and interpersonal difficulties.

重度抑郁障碍(MDD)和边缘型人格障碍(BPD)的特点是情绪和人际功能模式紊乱,这可能意味着在人际交往中使用情绪调节的方式发生了改变。在本研究中,我们考察了 MDD 和/或 BPD 患者与健康对照者在以下方面的差异:(1)他们在日常生活中使用表达性抑制和社交分享的总体情况;(2)他们根据情绪环境(即之前的消极和积极情绪)调整这些策略的使用的倾向。34 名 MDD 患者、20 名 BPD 患者、19 名合并 MDD 和 BPD 的患者以及 40 名健康对照者参加了为期一周的经验取样,在此期间,他们报告了表达性抑制和社交分享的使用情况,并体验了消极和积极情绪。结果显示,与健康对照组相比,所有临床组在日常生活中都报告了更多的表达压抑和社交分享。在控制了平均体验情感的差异后,组间差异依然存在,但多发性抑郁症患者的压抑增加,而双相情感障碍患者和合并有多发性抑郁症和双相情感障碍的患者的分享增加,这似乎与这些参与者整体较高的消极情感水平有关。此外,对于临床参与者和对照组参与者来说,消极或积极情绪的人际波动与随后的策略使用之间的关联同样强烈,这表明临床组并没有根据情绪环境对抑制和分享的使用进行不同的调整。总之,患有 MDD 和/或 BPD 的人在日常生活中会更多地使用压抑和分享,这可能是导致其情绪和人际交往困难的原因之一。
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引用次数: 0
Predictors of preoperative anxiety in pediatric surgical patients in Ghana: A bi-center study 加纳儿科手术患者术前焦虑的预测因素:双中心研究
Pub Date : 2024-06-30 DOI: 10.1002/mhs2.76
Richard Dei-Asamoa, Delali Fiagbe, Dzifa Dellor, Joseph Osafo

Anticipation of surgical procedures has been noted to be a major cause of anxiety, particularly in children and their parents. Preoperative anxiety in children is associated with complications before, during, and after surgery. There is therefore the need to identify predictors of preoperative anxiety in children, for early identification and development of interventions. This study aimed at determining predictors of preoperative anxiety in children. A total of 70 children with their parents, scheduled for general pediatric surgery in two teaching hospitals in Ghana, were recruited using a convenience sampling technique. Parental anxiety, perception of quality of healthcare, and preoperative anxiety in children were measured using the State Section of the State Trait Anxiety Inventory, the Pediatric Quality of Life—Healthcare Satisfaction Module, and the modified Yale Preoperative Anxiety Scale, respectively. Previous surgical experience, age and type of surgery were obtained by demographic questionnaire and hospital records. Majority of children who participated in the study were between ages 2 and 7 years (82.9%). 84.3% of parents in the study were females. Parental anxiety (β = 0.953, pp = 0.000) and perceived quality of healthcare (β = −0.257, p = 0.031) predicted preoperative anxiety in children. Older children scheduled for major surgery were more anxious in the preoperative period than younger children scheduled for major surgery (F = 6.75, p = 0.012). Comprehensive anxiety-alleviation protocols for pediatric surgery should involve parents as well as improving perceptions of quality of healthcare.

人们注意到,对手术过程的预期是导致焦虑的一个主要原因,尤其是对儿童及其父母而言。儿童的术前焦虑与术前、术中和术后的并发症有关。因此,有必要确定儿童术前焦虑的预测因素,以便及早识别和制定干预措施。本研究旨在确定儿童术前焦虑的预测因素。研究采用方便抽样技术,共招募了 70 名儿童及其父母,他们计划在加纳的两家教学医院接受普通儿科手术。分别使用国家特质焦虑量表的国家部分、儿科生活质量-医疗保健满意度模块和改良的耶鲁术前焦虑量表测量了家长的焦虑、对医疗保健质量的感知和儿童的术前焦虑。以前的手术经历、年龄和手术类型通过人口统计学问卷和医院记录获得。大部分参与研究的儿童年龄在 2 至 7 岁之间(82.9%)。84.3%的家长为女性。家长焦虑(β = 0.953,p = 0.000)和感知的医疗质量(β = -0.257,p = 0.031)可预测儿童的术前焦虑。计划接受大手术的大龄儿童比计划接受大手术的小龄儿童在术前更焦虑(F = 6.75,p = 0.012)。小儿外科手术的综合焦虑缓解方案应让家长参与进来,并提高对医疗质量的认识。
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引用次数: 0
Using passive and active data to predict posttraumatic stress disorder symptoms and cannabis use in recently discharged UK veterans: A protocol for the MAVERICK feasibility study 利用被动和主动数据预测最近退伍的英国退伍军人的创伤后应激障碍症状和大麻使用情况:MAVERICK 可行性研究方案
Pub Date : 2024-06-23 DOI: 10.1002/mhs2.75
Grace Williamson, Nora Trompeter, Dominic Murphy, Shaddy Saba, Eric R. Pedersen, Jordan P. Davis, Daniel Leightley

Posttraumatic stress disorder (PTSD) and comorbid cannabis use disorder (CUD) is a growing concern amongst UK veterans. Co-occurrence of problematic cannabis use, and PTSD is associated with greater PTSD symptom severity, decreased likelihood of cannabis use cessation, worse clinical outcomes, and increased societal burden. Despite increased screening efforts among veterans, there are no effective strategies for predicting risk for PTSD and problematic drug use escalation before these conditions develop, worsen, or become chronic. This feasibility study employs a 4-week (28-day) longitudinal design (daily data collection), multiple passive data collection features via a bespoke study smartphone app called MAVERICK, and active data collection via wearable technology to predict clinically meaningful escalations in cannabis use and PTSD symptoms in UK veterans. Questionnaire data will be collected between 06:00 a.m. and 10:00 a.m. each day. Passive data will be collected continuously in the background. The study will begin recruitment in June 2023 and will require 18 months to complete. Study results are expected to be published in January 2024. This trial will provide information on the feasibility and utility of a smartphone app (MAVERICK) to collect both active and passive data to predict PTSD symptoms and cannabis use in a UK veteran population. If the smartphone app is deemed feasible and acceptable to users, it has the potential to provide an effective measurement tool to mitigate risk of PTSD and problematic cannabis use among veterans.

在英国退伍军人中,创伤后应激障碍(PTSD)和合并大麻使用障碍(CUD)日益受到关注。同时出现问题性大麻使用和创伤后应激障碍与创伤后应激障碍症状更加严重、停止使用大麻的可能性降低、临床结果更差以及社会负担加重有关。尽管在退伍军人中加大了筛查力度,但目前还没有有效的策略来预测创伤后应激障碍和问题药物使用升级的风险,以免这些症状发展、恶化或成为慢性病。这项可行性研究采用了为期 4 周(28 天)的纵向设计(每天收集数据),通过名为 MAVERICK 的定制研究智能手机应用程序进行多种被动数据收集功能,并通过可穿戴技术进行主动数据收集,以预测英国退伍军人中具有临床意义的大麻使用和创伤后应激障碍症状的升级。问卷数据将在每天上午 6:00 至 10:00 之间收集。被动数据将在后台持续收集。研究将于 2023 年 6 月开始招募,需要 18 个月完成。研究结果预计将于 2024 年 1 月公布。这项试验将提供有关智能手机应用程序(MAVERICK)的可行性和实用性的信息,该应用程序可收集主动和被动数据,用于预测英国退伍军人群体中的创伤后应激障碍症状和大麻使用情况。如果该智能手机应用程序被认为可行并为用户所接受,那么它就有可能成为一种有效的测量工具,以降低退伍军人中出现创伤后应激障碍和使用问题大麻的风险。
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引用次数: 0
Assessing physiological arousal and emotional valence during behavioral intervention for pediatric feeding difficulties: A pilot study 评估儿科喂养困难行为干预过程中的生理唤醒和情绪情感:试点研究
Pub Date : 2024-06-20 DOI: 10.1002/mhs2.74
Laura E. Phipps PhD, Walker S. Arce MS, Seth G. Walker PhD, James E. Gehringer PhD

This study's purpose is to introduce a new measurement system that objectively assesses the social validity of behavioral feeding intervention from the child's perspective via the concurrent measurement of two dimensions of emotion. To date, the primary measures of social validity for behavioral feeding intervention are caregiver treatment acceptability and satisfaction surveys. This is the first study to objectively measure two dimensions of emotion, physiological arousal and emotional valence, while children received behavioral intervention for feeding difficulties. Data collectors used a new open-source data collection software, cometrics, developed to synchronize and record physiological and observational data. Physiological data was collected using a wearable biosensor and observers recorded an index of child happiness, unhappiness, or neither using definitions by Phipps et al. (2022) for six children with a pediatric feeding disorder. Two out of six children needed programmed habituation to the device before data collection. All children assented to wearing the device during data collection. Recorded indices mapped to separable physiological states using electrodermal activity and its constituent components, skin conductance responses and skin conductance level, in addition to skin temperature. Findings demonstrated the feasibility of measuring two dimensions of child emotions during behavioral feeding intervention and revealed that children's physiological responses were distinctly different during intervals scored as happy, unhappy, or neither. This new data collection system has implications for future research on the child's emotional experience of behavioral feeding treatment and increases the possibilities for improving clinical practice.

本研究旨在引入一套新的测量系统,通过同时测量两个维度的情绪,从儿童的角度客观评估行为喂养干预的社会有效性。迄今为止,行为喂养干预社会有效性的主要测量方法是护理人员对治疗的接受度和满意度调查。这是第一项客观测量儿童在接受喂养困难行为干预时的两个情绪维度(生理唤醒和情绪价位)的研究。数据收集人员使用了一种新的开源数据收集软件 cometrics,该软件可同步记录生理数据和观察数据。生理数据通过可穿戴生物传感器收集,观察者则根据菲普斯等人(Phipps et al. 2022)对六名患有小儿喂养障碍的儿童所下的定义,记录儿童的快乐、不快乐或都不快乐的指数。六名儿童中有两名需要在数据收集前通过编程适应该装置。所有儿童都同意在数据收集期间佩戴设备。除皮肤温度外,记录的指数还映射到可分离的生理状态,包括皮肤电活动及其组成成分、皮肤电导反应和皮肤电导水平。研究结果表明,在行为喂养干预过程中测量儿童情绪的两个维度是可行的,并揭示了儿童在快乐、不快乐或两者都不快乐的间歇期的生理反应是截然不同的。这一新的数据收集系统对今后研究儿童在行为喂养治疗中的情绪体验具有重要意义,并增加了改进临床实践的可能性。
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引用次数: 0
Significance of overvaluation of weight and shape in childhood binge-eating disorder: Results from a population-based study 高估体重和体型对儿童暴饮暴食症的影响:基于人群的研究结果
Pub Date : 2024-06-16 DOI: 10.1002/mhs2.73
Alejandra Baron, Kathryn E. Smith, Tyler B. Mason

Binge-eating disorder (BED) involves recurrent binge-eating episodes with significant distress and is associated with adverse psychological and social problems. Previous studies in adults have suggested that presence of overvaluation of shape and weight may be a clinically relevant subtype of BED. The purpose of this study was to examine if overvaluation represents an important subtype of BED in children. It was hypothesized that children with both BED and overvaluation will have a higher body mass index z-scores (BMI-z) and internalizing psychopathology and lower cognitive functioning scores. Participants included a diverse sample of children between the ages of 9 and 10 years old from the baseline wave of the Adolescent Brain Cognitive Development study. Caregivers completed the Kiddie Schedule for Affective Disorders and Schizophrenia, the Child Behavior Checklist, and measures of demographics, and children completed neurocognitive tests and had their height and weight measured. The analytic sample included 7200 children. There were no interactions between BED status and overvaluation in relation to outcome variables. Yet, BED and overvaluation were independently associated with higher internalizing symptoms, higher BMI-z, and poorer cognitive functioning. Contrary to the expectations, results did not support significant interactions between BED status and overvaluation in children. However, the study highlights the independent clinical significance of BED and overvaluation with higher BMI-z, higher internalizing symptoms, and poorer cognitive functioning. Future studies are necessary to determine the developmental trajectories of BED and overvaluation into adolescence and adulthood.

暴饮暴食症(BED)是指反复发作的暴饮暴食,并伴有明显的痛苦,与不良的心理和社会问题有关。以往对成人的研究表明,对体形和体重的高估可能是暴食症的一个临床相关亚型。本研究的目的是探讨高估体重是否是儿童 BED 的一个重要亚型。根据假设,同时患有BED和高估的儿童的体重指数z-分数(BMI-z)会更高,内化心理病理学和认知功能分数会更低。参与者包括青少年大脑认知发展研究基线波中 9 至 10 岁儿童的不同样本。照顾者完成了情感障碍和精神分裂症儿童时间表、儿童行为检查表和人口统计学测量,儿童完成了神经认知测试并测量了身高和体重。分析样本包括 7200 名儿童。在结果变量方面,BED状态和高估之间没有相互作用。然而,BED 和高估与较高的内化症状、较高的 BMI-z 和较差的认知功能独立相关。与预期相反,研究结果并不支持儿童的 BED 状态与高估之间存在显著的交互作用。然而,该研究强调了BED和高估与较高的BMI-z、较高的内化症状和较差的认知功能之间的独立临床意义。未来的研究有必要确定 BED 和高估进入青春期和成年期的发展轨迹。
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引用次数: 0
Warning signals for mental health problems in at-risk young adults may be informed by momentary emotions reported by the general population: A novel application of the principles of statistical process control 高危青少年心理健康问题的预警信号可能来自普通人群报告的瞬间情绪:统计过程控制原理的新应用
Pub Date : 2024-06-10 DOI: 10.1002/mhs2.72
Marieke J. Schreuder, Peter Kuppens, Evelien Schat, Peter de Jonge, Catharina A. Hartman, Eva Ceulemans

Statistical process control (SPC) was recently introduced as a method for detecting person-specific warning signals for mental ill-health. Such warning signals occur when a person's repeatedly assessed emotions exceed a control limit. This control limit should in principle be based on the same person's emotions in a healthy period. As such data are often unavailable, this preregistered study investigated whether general population data can be used instead to estimate control limits. We used data from the HowNutsAreTheDutch study, in which adults from the general population (N = 746) rated their emotions three times a day for 1 month. Based on these data, we computed control limits according to the exponentially weighted moving average (EWMA) and Shewhart SPC methods. Next, we investigated how often young adults with versus without persistent mental health problems from the TRAILS TRANS-ID study (N = 100)–who rated their emotions daily for 6 months–reported scores beyond these general population-based control limits. Generally, warning signals occurred more often in young adults with persistent mental health problems compared to healthy young adults (p < 0.05). The predictive performance of SPC did not consistently improve when control limits were conditioned on individuals' age, sex, and depressive symptoms, nor differ between methods (EWMA vs. Shewhart). The different emotions that were monitored, however, affected SPC performance, so that for most settings, warning signs in feeling tired and upset were worse for detecting mental-ill health compared to warning signs in other emotions (e.g., feeling nervous, relaxed, etc.).  It follows that warning signs in individual's emotions can perhaps be monitored using relatively generic norms, derived from the general population, opening up new avenues for research and low-threshold clinical application.

统计过程控制(SPC)是最近推出的一种检测特定人群精神疾病预警信号的方法。当一个人反复评估的情绪超过控制限度时,就会出现这种预警信号。原则上,该控制限值应基于同一人在健康时期的情绪。由于通常无法获得此类数据,这项预先登记的研究调查了是否可以使用普通人群数据来估算控制限值。我们使用了 "HowNutsAreTheDutch "研究的数据,在这项研究中,普通人群中的成年人(N = 746)每天三次对自己的情绪进行评分,为期一个月。根据这些数据,我们按照指数加权移动平均法(EWMA)和Shewhart SPC法计算了控制限。接下来,我们调查了 TRAILS TRANS-ID 研究(N = 100)中有持续性心理健康问题和无持续性心理健康问题的年轻人(他们在 6 个月内每天都对自己的情绪进行评分)报告的分数超出这些基于一般人群的控制限值的频率。一般来说,与健康的年轻人相比,有持续性心理健康问题的年轻人出现预警信号的频率更高(P < 0.05)。根据个人的年龄、性别和抑郁症状设定控制限时,SPC 的预测性能并没有持续提高,不同方法(EWMA 与 Shewhart)之间也没有差异。然而,所监测的不同情绪会影响 SPC 的性能,因此在大多数情况下,与其他情绪(如紧张、放松等)的警示信号相比,疲倦和不安的警示信号更不利于检测精神疾病。 由此可见,个人情绪中的警示信号或许可以使用从普通人群中得出的相对通用的标准进行监测,从而为研究和低门槛临床应用开辟新的途径。
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引用次数: 0
Identifying protective factors related to burnout, moral injury, and resilience of registered nurses: An exploratory analysis 确定与注册护士的职业倦怠、道德伤害和复原力有关的保护性因素:探索性分析
Pub Date : 2024-05-28 DOI: 10.1002/mhs2.71
Sara L. Hubbell DNP, APRN, FNP-C, PMHNP-BC, Susan E. Young PhD, RN, PHNA-BC, Stephanie R. Duea PhD, RN, Christopher R. Prentice PhD

Nursing leadership continue to grapple with the pre-existing social, physical, spiritual, and emotional toll experienced by the nursing workforce, further exacerbated by the pandemic. The three-fold purpose of this current quantitative study was to measure the impact of the pandemic on nurses’ levels of burnout, moral injury, and resilience; measure levels of compassion satisfaction, and secondary traumatic stress; and identify protective factors against burnout and moral injury that could bolster resilience. An electronic survey was created using three validated instruments and sent to nurses in one US state. Bivariate and multivariate analyses were performed. Survey response rate was 5.5%. Respondents reported high levels of burnout and moral injury, and reduced levels of resilience. Protective factors included age, experience, education, and religion, with the older, more experienced, and educated nurse who identified as Christian being found to represent the most protected group. Multipronged strategies are needed to support, sustain, and recover nurses’ mental health across demographics to meet current and future workforce needs.

护理领导层仍在努力解决护理人员在社会、身体、精神和情感方面所经历的原有问题,而大流行病进一步加剧了这些问题。本定量研究的三重目的是测量大流行病对护士的职业倦怠、精神伤害和复原力水平的影响;测量同情满意度和继发性创伤压力的水平;以及识别可增强复原力的防止职业倦怠和精神伤害的保护因素。我们使用三种经过验证的工具制作了一份电子调查表,并发送给美国一个州的护士。进行了双变量和多变量分析。调查回复率为 5.5%。受访者表示职业倦怠和精神伤害程度较高,复原力水平较低。保护因素包括年龄、经验、教育程度和宗教信仰,其中年龄较大、经验较丰富、教育程度较高且信奉基督教的护士是最受保护的群体。需要采取多管齐下的策略来支持、维持和恢复不同人口群体护士的心理健康,以满足当前和未来的劳动力需求。
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引用次数: 0
Change blindness, reward bias, negative affective priming: Exploring individual-level associations between depression/anxiety symptoms and cognition 变化盲点、奖赏偏差、负面情绪引物:探索抑郁/焦虑症状与认知之间的个体层面关联
Pub Date : 2024-05-26 DOI: 10.1002/mhs2.70
Annamaria Balogh, Glyn Lewis, Roz Shafran, Oliver J. Robinson

Cognitive biases are thought to contribute to depression/anxiety. In addition to self-reported measures, cognitive tasks could potentially be integrated with clinical practice as more precise measures of cognitive biases. In a large online study we explored the individual-level association between depression/anxiety symptoms and performance on (1) reward bias, (2) negative affective priming, and (3) change blindness tasks. Participants completed tasks alongside depression/anxiety symptom questionnaires. We used regression analyses to test for associations between task performance and questionnaire scores. We conducted a replication study of the change blindness task, and performed a mega-analysis of the two studies. Faster reaction time in the change blindness task was associated with higher depression score (B = −27, p = 0.034) in the first study (N = 545) and higher depression and anxiety scores (depression: B = −15, p = 0.045; anxiety: B = −17, p = 0.022) in the replication study (N = 616). These effects were significant in the mega-analysis but did not withstand adjusting for age in either the original and replication studies or the mega-analysis. We found no association between depression/anxiety and reward bias (N = 504) and negative affective priming (N = 539). Our results provide preliminary evidence that individuals with more severe depressive/anxious symptoms may be faster at identifying changes in the change blindness task. Contrary to previous findings, neither reward bias nor negative affective priming was associated with depression/anxiety.

认知偏差被认为是导致抑郁/焦虑的原因之一。除了自我报告的测量方法外,认知任务也有可能与临床实践相结合,成为认知偏差的更精确测量方法。在一项大型在线研究中,我们探讨了抑郁/焦虑症状与(1)奖赏偏差、(2)消极情绪引物和(3)变化盲任务表现之间的个体水平关联。参与者在完成任务的同时还填写了抑郁/焦虑症状问卷。我们使用回归分析来检验任务表现与问卷得分之间的关联。我们对变化盲任务进行了重复研究,并对这两项研究进行了大规模分析。在第一项研究(545 人)中,变化盲任务中更快的反应时间与更高的抑郁得分相关(B = -27,p = 0.034),在重复研究(616 人)中,更高的抑郁和焦虑得分相关(抑郁:B = -15,p = 0.045;焦虑:B = -17,p = 0.022)。这些影响在大型分析中具有显著性,但在原始研究、复制研究或大型分析中都经不起年龄调整。我们发现,抑郁/焦虑与奖赏偏差(504 人)和负面情绪引物(539 人)之间没有关联。我们的研究结果提供了初步证据,表明抑郁/焦虑症状更严重的人可能在变化盲任务中识别变化的速度更快。与之前的研究结果相反,奖赏偏差和消极情绪引物都与抑郁/焦虑无关。
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引用次数: 0
The maintenance of complex visual scenes in working memory may require activation of working memory manipulation circuits in the dlPFC: A preliminary report 要在工作记忆中保持复杂的视觉场景,可能需要激活大脑前部皮层的工作记忆操纵回路:初步报告
Pub Date : 2024-05-10 DOI: 10.1002/mhs2.61
Frederick Nitchie, Abigail Casalvera, Marta Teferi, Milan Patel, Kevin G. Lynch, Walid Makhoul, Yvette I. Sheline, Nicholas L. Balderston

Past research has shown that the bilateral dorsolateral prefrontal cortices (dlPFC) are implicated in both emotional processing as well as cognitive processing,1,2,3 in addition to working memory4, 5. Exactly how these disparate processes interact with one another within the dlPFC is less understood. To explore this, we designed a task that looked at working memory performance during fMRI under both emotional and nonemotional conditions, and tested it in this preliminary report. Participants were asked to complete three tasks (letters, neutral images, emotional images) of the Sternberg Sorting Task under one of two trial conditions (sort or maintain). Regions of interest consisted of the left and right dlPFC as defined by brain masks based on NeuroSynth6. Results showed a significant main effect of the ‘sort’ condition on reaction speed for all three trial types, as well as a main effect of task type (letters) on accuracy. In addition, a significant interaction was found between trial type (sort) and task type (letters), but not for either of the picture tasks. Although preliminary, these results reveal a discrepancy between BOLD signal and behavioral data, with no significant difference in BOLD activity during image trials being displayed, despite longer response times for every condition. While these initial results show that the dlPFC is implicated in nonemotional cognitive processing, more research is needed to explain the lack of BOLD activation seen here for similar emotionally valanced tasks, possibly indicating the involvement of other brain networks.

过去的研究表明,双侧背外侧前额叶皮层(dlPFC)与情绪处理和认知处理1,2,3 以及工作记忆4,5 都有关系。这些不同的过程究竟如何在前额叶皮质内相互作用,目前还不太清楚。为了探究这个问题,我们设计了一项任务,考察在情绪和非情绪条件下的 fMRI 工作记忆表现,并在本初步报告中进行了测试。我们要求受试者在两种试验条件(排序或保持)之一下完成斯腾伯格排序任务的三个任务(字母、中性图像、情绪图像)。研究区域包括基于 NeuroSynth6 的脑掩膜所定义的左右大脑前交叉区域(dlPFC)。结果表明,在所有三种试验类型中,"排序 "条件对反应速度有明显的主效应,任务类型(字母)对准确性也有明显的主效应。此外,试验类型(排序)和任务类型(字母)之间存在明显的交互作用,但对图片任务没有影响。这些结果虽然是初步的,但揭示了 BOLD 信号和行为数据之间的差异,尽管每种条件下的反应时间都较长,但在图像试验中显示的 BOLD 活动没有明显差异。虽然这些初步结果表明,dlPFC 与非情绪认知处理有关联,但还需要更多的研究来解释为什么在类似的情绪估值任务中缺乏 BOLD 激活,这可能表明有其他大脑网络参与其中。
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引用次数: 0
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Mental health science
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