Natural Remedies for Onychomycosis: A Review

Q4 Pharmacology, Toxicology and Pharmaceutics Journal of Natural Remedies Pub Date : 2023-11-05 DOI:10.18311/jnr/2023/33695
Chitrali R. Talele, Dipali R. Talele, Gargee Barhate, Vasudev Bendre, Vedant Marda, Chirag Khandelwal
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Abstract

Onychomycosis, a fungus that causes nail colouring, nail separation, and nail plate growth, has infected the nail unit. There is a chance that the nail structure, nail bed, or nail layer could be infected. The term “onychomycosis” derives from the Greek words “onyx” (nail) and “mykes” (fungus). Around 50% of all consultations for nail diseases are for onychomycosis, the most common nail infection disorder. About 90% of toenail onychomycosis and 75% of fingernail onychomycosis are caused by dermophytes like Trichophyton rubrum and Trichophyton mentagrophytes. About 70% of yeast-borne onychomycosis cases are caused by Candida albicans. Epidemiological studies that have just been released estimate that onychomycosis affects every community worldwide at a rate of about 5.5 per cent. Onychomycosis is managed in different ways based on clinical categorization, the number of damaged nails, and the severity of the condition. The disadvantages of treatment are that oral therapies are frequently limited by drug interactions and probable hepatotoxicity, and topical antifungals have low efficacy if administered without nail plate biosurgery. The use of plants in medical treatments and herbal therapies is one of the less harmful, cheaper, and widely available alternatives to synthetic pharmaceuticals for treating fungal infections. Undoubtedly, dermatophytes can be inhibited by plant-based extracts as well as essential oils’ antifungal activities.
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甲真菌病的自然疗法:综述
甲真菌病是一种导致指甲着色、指甲分离和甲板生长的真菌,已经感染了指甲单位。指甲结构、甲床或甲层有可能被感染。“甲真菌病”一词来源于希腊语“onyx”(指甲)和“mykes”(真菌)。大约50%的指甲疾病咨询是针对甲真菌病,这是最常见的指甲感染疾病。大约90%的脚趾甲真菌病和75%的指甲甲真菌病是由毛癣菌和毛癣菌等皮肤真菌引起的。大约70%的酵母菌传播的甲癣病例是由白色念珠菌引起的。刚刚公布的流行病学研究估计,甲真菌病影响全世界每个社区的发病率约为5.5%。根据临床分类、受损指甲的数量和病情的严重程度,治疗甲真菌病的方法不同。治疗的缺点是口服治疗经常受到药物相互作用和可能的肝毒性的限制,如果不进行甲板生物手术,局部抗真菌药物的疗效很低。在医学治疗和草药疗法中使用植物是治疗真菌感染的合成药物的一种危害更小、更便宜和广泛可用的替代品。毫无疑问,植物提取物和精油的抗真菌活性可以抑制皮肤真菌。
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来源期刊
Journal of Natural Remedies
Journal of Natural Remedies Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
0.40
自引率
0.00%
发文量
27
期刊介绍: Nature can provide all the remedies, for all. All substances produced by nature can be recognized; all cells talk the same language as we all are from the same mother cell. Journal of Natural Remedies is devoted toward the understandings of all remedies from nature. Journal of Natural Remedies publishes original articles related to utilisation of any natural source for remedy including bioactive natural products. Studies related to the resources, chemistry (including analytical), biological activity, biotechnology and pharmacology (including toxicology) of archaea, bacteria, protistas, fungi, plants, animals, viruses and minerals fall within the journal’s scope.
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