A review of the analytical techniques for the detection of anabolic–androgenic steroids within biological matrices

IF 2.1 Q1 CRIMINOLOGY & PENOLOGY WIREs. Forensic science Pub Date : 2023-10-03 DOI:10.1002/wfs2.1504
Richard L. Harries, Giorgia De Paoli, Sarah Hall, Lorna A. Nisbet
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Abstract

Abstract Anabolic–androgenic steroids (AASs) and other image and performance enhancing drugs (IPEDs) are controlled by governments and sport institutions such as the World Anti‐doping Agency (WADA). Although elite athletes and professional bodybuilders are the most visible AAS abusers, the introduction of the internet has increased the accessibility of AASs, with use being observed among recreational gym goers at increasing prevalence. Despite reported increase in use, routine analysis for these substances is uncommon, with many forensic laboratories opting to outsource AAS analysis. This review collates information regarding the extraction and analysis of AASs from various biological matrices with the considered purpose of providing a reference for the development of AAS methods to allow for routine detection by forensic laboratories. This article is categorized under: Toxicology > in Sport Toxicology > Analytical
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生物基质中合成代谢雄激素类固醇检测分析技术综述
合成代谢雄激素类固醇(AASs)和其他图像和性能增强药物(iped)由政府和体育机构控制,如世界反兴奋剂机构(WADA)。虽然精英运动员和专业健美运动员是最明显的AAS滥用者,但互联网的引入增加了AAS的可及性,在休闲健身爱好者中使用AAS的情况越来越普遍。尽管有报道称使用增加,但对这些物质的常规分析并不常见,许多法医实验室选择外包原子吸收光谱分析。本综述整理了有关从各种生物基质中提取和分析AAS的信息,目的是为开发AAS方法提供参考,以便法医实验室进行常规检测。本文分类如下:毒理学;运动毒理学杂志;分析
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