Mathematical modeling for solving fractional model cancer bosom malignant growth

IF 1.1 Q4 BIOPHYSICS AIMS Biophysics Pub Date : 2023-01-01 DOI:10.3934/biophy.2023018
Shaimaa A. M. Abdelmohsen, D. Sh. Mohamed, Haifa A. Alyousef, M. R. Gorji, Amr M. S. Mahdy
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引用次数: 1

Abstract

In this essay, we have presented a fractional numerical model of breast cancer stages with cardiac outcomes. Five compartments were used to build the model, each of which represented a subpopulation of breast cancer patients. Variables A, B, C, D, and E each represent a certain subpopulation. They are levels 1 and 2 (A), level 3 (B), level 4 (C), disease-free (D) and cardiotoxic (E). We have demonstrated that the fractional model has a stable solution. We also discuss how to optimally control this model and numerically simulate the control problem. Using numerical simulations, we computed the results of the dissection. The model's compartment diagram has been completed. A predictor-corrector method has been used to manage the fractional derivatives and produce numerical solutions. The Caputo sense has been used to describe fractional derivatives. The results have been illustrated through numerical simulations. Furthermore, the numerical simulations show that the cancer breast malignant growth fractional order model is easier to model than the traditional integer-order model. To compute the results, we have used mathematical programming. We have made it clear that the numerical method that was applied in this publication to solve this model was not utilized by any other author before that, nor has this method been investigated in the past. Our investigation established this approach.

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求解分数型乳腺癌胸部恶性生长的数学模型
& lt; abstract>在这篇文章中,我们提出了乳腺癌分期与心脏预后的分数数值模型。五个隔间被用来建立模型,每个隔间代表乳腺癌患者的一个亚群。变量A、B、C、D和E分别代表一个特定的子群体。它们分别是1级和2级(A), 3级(B), 4级(C),无病(D)和心脏毒性(E)。我们已经证明分数模型有一个稳定的解。讨论了如何对该模型进行最优控制,并对控制问题进行了数值模拟。通过数值模拟,我们计算了解剖的结果。模型的隔室图已经完成。一种预测校正方法被用来处理分数阶导数并产生数值解。卡普托意义已被用来描述分数阶导数。结果通过数值模拟得到了验证。此外,数值模拟表明,乳腺癌恶性生长分数阶模型比传统的整数阶模型更容易建模。为了计算结果,我们使用了数学规划。我们已经明确表示,在此之前,没有任何其他作者使用过本文中用于求解该模型的数值方法,也没有研究过该方法。我们的调查确立了这种方法。</p>& lt; / abstract>
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来源期刊
AIMS Biophysics
AIMS Biophysics BIOPHYSICS-
CiteScore
2.40
自引率
20.00%
发文量
16
审稿时长
8 weeks
期刊介绍: AIMS Biophysics is an international Open Access journal devoted to publishing peer-reviewed, high quality, original papers in the field of biophysics. We publish the following article types: original research articles, reviews, editorials, letters, and conference reports. AIMS Biophysics welcomes, but not limited to, the papers from the following topics: · Structural biology · Biophysical technology · Bioenergetics · Membrane biophysics · Cellular Biophysics · Electrophysiology · Neuro-Biophysics · Biomechanics · Systems biology
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