Rabbit model for the study of nasal tip plasty: a comparative cephalometric analysis after rhinoplasty

Pub Date : 2023-10-31 DOI:10.14730/aaps.2023.00794
Myung-Good Kim, Jeong-Ho Ryu, Dong Min Lee, Tae-Seo Park, Ji-An Choi
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Abstract

Background Open rhinoplasty and septoplasty have emerged as popular surgical techniques for both functional and aesthetic procedures. To study open rhinoplasty with or without septoplasty, the use of animals is necessary. However, no reports have been published on radiologic methods for evaluating rhinoplasty or nasal tip plasty in animals using cephalometry. In this study, a validated model of open rhinoplasty and septoplasty was utilized in rabbits to establish radiographic guidelines for assessing the degree of tip plasty in these animals.Methods Eight adult New Zealand rabbits were used to establish an autologous septal extension graft (SEG) model. The rabbits underwent concurrent submucosal septal resection and open rhinoplasty. The SEG was implanted using nasal septal cartilage. To evaluate the results of nasal tip plasty, lateral-view X-ray images were obtained preoperatively, as well as 2 days, 2 months, and 12 months postoperatively.Results This open rhinoplasty rabbit model appears to be a practical tool for studying open rhinoplasty and tip plasty, demonstrating statistically significant results following SEG implantation. Furthermore, it is suitable for training purposes, specifically for the submucosal resection of septal cartilage.Conclusions This study presents a statistical analysis of the long-term (1-year) postoperative results of SEG implantation, using experimental procedures like those utilized in humans. Through a cephalometric comparison of rabbit noses, the effect of various SEG and tip plasty methods on the rabbit nose can be objectively measured.
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兔鼻尖成形术研究模型:鼻尖成形术后头颅测量的对比分析
背景开放式鼻成形术和鼻中隔成形术已成为功能性和美学手术的流行手术技术。为了研究有或没有鼻中隔成形术的开放式鼻成形术,动物的使用是必要的。然而,目前还没有关于使用头颅测量术评估动物鼻整形或鼻尖整形的放射学方法的报道。在这项研究中,我们在兔子身上建立了一个经过验证的开放鼻整形和鼻中隔成形术模型,以建立评估这些动物鼻尖成形术程度的放射学指南。方法8只成年新西兰兔建立自体中隔延伸移植(SEG)模型。同时行粘膜下鼻中隔切除术和开放鼻成形术。SEG采用鼻中隔软骨植入。为了评价鼻尖成形术的效果,术前、术后2天、2个月和12个月分别获得侧位x线图像。结果该开放鼻整形兔模型是研究开放鼻整形和鼻尖整形的实用工具,SEG植入后的结果具有统计学意义。此外,它适用于训练目的,特别是隔膜软骨的粘膜下切除术。本研究采用类似于人类的实验程序,对SEG植入术后长期(1年)的结果进行了统计分析。通过兔鼻的头颅测量比较,可以客观地衡量各种SEG和鼻尖成形术对兔鼻的影响。
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