Herbal Remedies for Osteoporosis

Q4 Pharmacology, Toxicology and Pharmaceutics Journal of Natural Remedies Pub Date : 2023-11-03 DOI:10.18311/jnr/2023/34056
Maitri Mahant, Sweta B. Besh, Divya Kanojiya, Cyril Sajan, Hemrajsingh Rajput, Rajesh A. Maheshwari
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Abstract

Osteoporosis is a widespread concern that poses significant health risks. In the past, it was commonly thought that women would naturally undergo this condition as they age, especially during menopause when hormonal imbalances heighten the risk. Osteoporotic fractures affect approximately one in three women and one in five men over the age of 50 during their lifetimes. The mature skeleton constantly undergoes a remodelling process that involves both bone formation and resorption. However, when bone resorption exceeds bone growth, osteoporosis develops. Both men and women need to prioritize their bone health throughout their lives. Addressing factors that impact bone health at every stage becomes crucial in preventing osteoporosis. To combat the rising incidence of osteoporotic fractures, it is crucial to implement effective preventive measures aimed at maximizing peak bone density, limiting accelerated bone loss, and reducing the risk of falls. Present therapy goals primarily focus on stopping further bone loss and fractures, preserving bone mass, and utilizing medications like bisphosphonates, Selective Estrogen Receptor Modulators (SERMs), anabolic steroids, strontium, and Hormonal Replacement Therapy (HRT). However, it’s worth noting that some of these treatments, such as HRT, bisphosphonates, SERMs, and anabolic steroids, may have negative side effects. As a result, there is an urgent need to identify effective, affordable, natural, and less harmful compounds to manage osteopenia/osteoporosis effectively. The search for safer alternatives is crucial in combating this condition and promoting better bone health.
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骨质疏松症的草药疗法
骨质疏松症是一个广泛关注的健康问题。过去,人们普遍认为,随着年龄的增长,女性会自然而然地患上这种疾病,尤其是在荷尔蒙失衡加剧风险的更年期。在50岁以上的人群中,大约有三分之一的女性和五分之一的男性患有骨质疏松性骨折。成熟的骨骼不断经历一个包括骨形成和骨吸收的重塑过程。然而,当骨吸收超过骨生长时,骨质疏松症就会发生。男性和女性在一生中都需要优先考虑骨骼健康。在每个阶段解决影响骨骼健康的因素对于预防骨质疏松症至关重要。为了对抗骨质疏松性骨折发病率的上升,实施有效的预防措施是至关重要的,这些措施旨在最大限度地提高峰值骨密度,限制骨质加速流失,减少跌倒的风险。目前的治疗目标主要集中在阻止进一步的骨质流失和骨折,保留骨量,并使用双膦酸盐、选择性雌激素受体调节剂(SERMs)、合成代谢类固醇、锶和激素替代疗法(HRT)等药物。然而,值得注意的是,其中一些治疗方法,如HRT,双膦酸盐,serm和合成代谢类固醇,可能有负面副作用。因此,迫切需要找到有效的、负担得起的、天然的、危害较小的化合物来有效地治疗骨质减少/骨质疏松症。寻找更安全的替代品对于对抗这种情况和促进更好的骨骼健康至关重要。
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来源期刊
Journal of Natural Remedies
Journal of Natural Remedies Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
0.40
自引率
0.00%
发文量
27
期刊介绍: Nature can provide all the remedies, for all. All substances produced by nature can be recognized; all cells talk the same language as we all are from the same mother cell. Journal of Natural Remedies is devoted toward the understandings of all remedies from nature. Journal of Natural Remedies publishes original articles related to utilisation of any natural source for remedy including bioactive natural products. Studies related to the resources, chemistry (including analytical), biological activity, biotechnology and pharmacology (including toxicology) of archaea, bacteria, protistas, fungi, plants, animals, viruses and minerals fall within the journal’s scope.
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