Rivaroxaban: Management of Coronary Artery Thrombosis in a Patient Presenting with Anterior Wall Myocardial Infarction

Ayesha Tariq, Bilqees Akhtar, Asma Sharif
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Abstract

Coronary artery thrombosis is one of the most common clinically manifested disease that if not treated timely leads to morbidity and mortality particularly stroke or myocardial infarction. Anti-platelets are already the first line of treatment that are adopted for the prevention of coronary artery thrombosis however, there is need of a novel and potent anticoagulant that could help to reduce the frequency of coronary or atherothrombotic events in patients presenting with coronary diseases. Case Summary: We present a case of anterior wall myocardial infarction (AWMI) driven by coronary artery thrombosis. The patient upon diagnosis was found to have a clot in proximal left anterior descending artery (LAD). The patient was treated and discharged on anticoagulation therapy. We examined and report the effectiveness of anticoagulation therapy via a novel oral anticoagulant. i.e. Rivaroxaban for managing the risk of coronary artery thrombosis associated with AWMI within our patient. Onset of coronary artery thrombosis is associated with the mortality in myocardial infarct patients, regardless of its timing. This calls out for the need to manage the disease by adopting strategies that would prevent the frequent onset of these events in myocardial infarction survivors. Treatment with Rivaroxaban has emerged as a promising oral anticoagulant that could potentially serve as a long-term anticoagulant for managing coronary artery thrombosis in patients with heart complications.
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利伐沙班:前壁心肌梗死患者冠状动脉血栓的治疗
冠状动脉血栓形成是临床上最常见的疾病之一,如果不及时治疗,会导致发病和死亡,特别是中风或心肌梗死。抗血小板已经成为预防冠状动脉血栓形成的一线治疗手段,然而,需要一种新型有效的抗凝剂,以帮助降低冠状动脉疾病患者发生冠状动脉或动脉粥样硬化血栓事件的频率。病例总结:我们报告一例由冠状动脉血栓形成引起的前壁心肌梗死。患者在诊断时发现左前降支近端有血栓。患者经治疗出院后接受抗凝治疗。我们检查并报告了一种新型口服抗凝剂抗凝治疗的有效性。即利伐沙班用于控制与AWMI相关的冠状动脉血栓形成的风险。冠状动脉血栓形成与心肌梗死患者的死亡率相关,与发病时间无关。这就需要通过采取策略来控制疾病,防止心肌梗死幸存者频繁发生这些事件。利伐沙班治疗已成为一种很有前途的口服抗凝剂,有可能作为治疗心脏并发症患者冠状动脉血栓形成的长期抗凝剂。
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