Laura Torrejón-Rodríguez, Álvaro Solaz-García, Inmaculada Lara-Cantón, Alejandro Pinilla-González, Marta Aguar, Máximo Vento
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引用次数: 0
Abstract
Abstract Extreme preterm infants (<28 weeks' gestation) often require positive pressure ventilation with oxygen during postnatal stabilization in the delivery room. To date, optimal inspired fraction of oxygen (FiO 2 ) still represents a conundrum in newborn care oscillating between higher (>60%) and lower (<30%) initial FiO 2 . Recent evidence and meta-analyses have underscored the predictive value for survival and/or relevant clinical outcomes of the Apgar score and the achievement of arterial oxygen saturation measured by pulse oximetry ≥85% at 5 minutes after birth. New clinical trials comparing higher versus lower initial FiO 2 have been launched aiming to optimize postnatal stabilization of extreme preterm while avoiding adverse effects of hypoxemia or hyperoxemia.
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