A literature Study on Association of Environmental Toxic Compounds with Thyroid Disruption

Abstract

The literature evidences showed a drastic effect of environmental chemicals compounds on the status of thyroid hormones. Most of the environmental chemical compounds mentioned in study show structural resemblance with thyroid hormones. Therefore, these chemicals can mimic the activity of thyroid hormones. Some chemical compounds also exhibit other mechanism; however, the exact mechanism of action is not cleared yet. Most commonly these chemicals include a dose dependent inhibition of thyroid hormones. No doubt these chemical compounds have beneficial roles at industrial scale where these are used in the preparation of various useful things but we cannot ignore their life-threatening consequences.