Analysis of the influence of selected protein parameters that are markers of nutritional statusand inflammatory markers on the occurrence of wound dehiscence after laparotomy.

Abstract

Wound dehiscence is a relatively rare complication after laparotomy consisting of dissection of thepost-operative wound and prolapse of the viscera outside the abdominal cavity and has been shownto be associated with a higher mortality rate. Known risk factors for this condition includemalnutrition and the coexistence of inflammation or cancer.The main purpose of this thesis was to investigate the association between the occurrence of postlaparotomy and the nutritional status of the patient as expressed by selected protein markers.The study was retrospective and based on an analysis of patients treated at the in-house centre fromJanuary 2014 to December 2020. It included a group of patients undergoing laparotomy procedureswho developed evectasia and a group of control group of patients who underwent laparotomy anddid not develop wound dehiscence after the procedure.The analysis showed that lower serum albumin levels were associated with a higher risk of wounddehiscence in patients who underwent laparotomy due to acute abdominal disease. The study andcontrol groups differed significantly in levels of: Hgb, total protein, CRP, lymphocytes, albumin, PCT,NRS.