Therapies that Have Shown Efficacy Against COVID-19: A Narrative Review

Abstract

Background: The new coronavirus disease has accelerated the development of therapeutic guidelines for patients depending on their degree of severity. To date, many drugs have been studied. However, as time passed, only some of these therapeutic groups have been effective and have produced a reduction in patient mortality and morbidity. Methods: A search and identification of articles published in the following electronic data-bases was carried out: PubMed, Clinical Key, Web of Science, and Scopus; for their analysis and selection in English and Spanish. The literature research emphasizes the search for current guidelines on the treatment of COVID-19, including all degrees of severity, seeking the effectiveness of the medication. Results: For each listed drug, its pharmacodynamics, pharmacokinetics, and general re-commendations for use in adult patients with COVID-19, are described. Conclusions: Du-ring the COVID-19 pandemic, numerous groups of drugs have been studied, however, only a select group have shown to have a role in the treatment of the disease. The literature and guidelines support the use of these treatments.