Regulation of Thyroid Hormone: An Important Aspect During Pregnancy

IF 0.3 Q4 OBSTETRICS & GYNECOLOGY Current Women s Health Reviews Pub Date : 2023-09-11 DOI:10.2174/1573404820666230908092540
Parul Pamma, Sricha Singh, Sakshi Sharma
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Abstract

Abstract: This paper provides a synopsis of maternal and fetal thyroid hormone stimulation during pregnancy. Treatment of thyroid illness during pregnancy is critical for avoiding negative maternal and fetal outcomes. Thyroid disorders are frequently asymptomatic and difficult to detect without specialized monitoring programs. Even mild maternal thyroid hormone insufficiency can result in fetal neurodevelopment difficulties. The thyroid is over-stimulated during pregnancy, resulting in alterations in thyroid hormone concentrations. Accurate thyroid function testing during pregnancy is crucial for both initiating thyroid hormone therapy and adjusting thyroid hormone dose in people who are already on thyroid hormone. Trimester-specific intervals are particularly critical during pregnancy, when thyroid insufficiency has been linked to poor obstetric outcomes and neuro-developmental impairments in the fetus. Knowing the natural changes in hormone concentrations that occur throughout pregnancy allows for customized supplementation of iodine when needed.
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甲状腺激素的调节:怀孕期间的一个重要方面
摘要:本文就妊娠期间母体和胎儿甲状腺激素的刺激进行综述。妊娠期间甲状腺疾病的治疗对于避免母体和胎儿的不良结局至关重要。甲状腺疾病通常是无症状的,没有专门的监测程序很难发现。即使轻微的母亲甲状腺激素不足也会导致胎儿神经发育困难。怀孕期间甲状腺受到过度刺激,导致甲状腺激素浓度的改变。怀孕期间准确的甲状腺功能检测对于启动甲状腺激素治疗和调整已经使用甲状腺激素的人的甲状腺激素剂量至关重要。妊娠期的特定间隔尤为重要,因为甲状腺功能不全与不良的产科结局和胎儿神经发育障碍有关。了解整个孕期激素浓度的自然变化,可以在需要时定制补充碘。
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来源期刊
Current Women s Health Reviews
Current Women s Health Reviews OBSTETRICS & GYNECOLOGY-
CiteScore
0.70
自引率
25.00%
发文量
67
期刊介绍: Current Women"s Health Reviews publishes frontier reviews on all the latest advances on obstetrics and gynecology. The journal"s aim is to publish the highest quality review articles dedicated to research in the field. The journal is essential reading for all clinicians and researchers in the fields of obstetrics and gynecology.
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