Diniwati Mukhtar, Aan Royhan, Hasna Luthfiah Fitriani, Melasari Marantika, Dita Safira Salsabila, Lena Fitriyana, Febri Irwansyah
{"title":"Effects of high glucose, egg yolk intake, calorie restriction, and air pollution on rats’ fat cell","authors":"Diniwati Mukhtar, Aan Royhan, Hasna Luthfiah Fitriani, Melasari Marantika, Dita Safira Salsabila, Lena Fitriyana, Febri Irwansyah","doi":"10.20885/jkki.vol14.iss1.art10","DOIUrl":null,"url":null,"abstract":"Background: Obesity is one of the cardiovascular disease risk factors that cause hypertrophy or hyperplasia of adipocytes. Changes in fat cells have the potential to increase inflammation and insulin resistance. Objective: This study aims to determine the effects of high glucose, egg yolk consumption, calorie restriction, and air pollution on body weight, cell size, and fat tissue weight in rats. Methods: The type of study is experimental and conducted for six weeks. Thirty white male rats were divided into five groups: sugar-treated group, egg yolk-treated group, restricted calorie intake-treated group, air pollutant-treated group, and control group. The cell size and weight of adipose tissue were obtained from abdominal and supraclavicular fat samples.Results: High glucose, egg yolk consumption, air pollution exposure, and calorie restriction were affected by increases in body weight, cell size, and adipose tissue mass (p < 0.05). The cell size and weight of adipose tissue have a negative effect on body mass index. Nevertheless, dietary intervention studies have shown that the size of fat cells decreases after calorie restriction-induced weight loss. Conclusion: The body weight, cell size, and adipose tissue weight of the rats were affected by a high sugar intake, egg yolk consumption, calorie restriction, and exposure to air pollution.","PeriodicalId":32915,"journal":{"name":"JKKI Jurnal Kedokteran dan Kesehatan Indonesia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JKKI Jurnal Kedokteran dan Kesehatan Indonesia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20885/jkki.vol14.iss1.art10","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Obesity is one of the cardiovascular disease risk factors that cause hypertrophy or hyperplasia of adipocytes. Changes in fat cells have the potential to increase inflammation and insulin resistance. Objective: This study aims to determine the effects of high glucose, egg yolk consumption, calorie restriction, and air pollution on body weight, cell size, and fat tissue weight in rats. Methods: The type of study is experimental and conducted for six weeks. Thirty white male rats were divided into five groups: sugar-treated group, egg yolk-treated group, restricted calorie intake-treated group, air pollutant-treated group, and control group. The cell size and weight of adipose tissue were obtained from abdominal and supraclavicular fat samples.Results: High glucose, egg yolk consumption, air pollution exposure, and calorie restriction were affected by increases in body weight, cell size, and adipose tissue mass (p < 0.05). The cell size and weight of adipose tissue have a negative effect on body mass index. Nevertheless, dietary intervention studies have shown that the size of fat cells decreases after calorie restriction-induced weight loss. Conclusion: The body weight, cell size, and adipose tissue weight of the rats were affected by a high sugar intake, egg yolk consumption, calorie restriction, and exposure to air pollution.