Steroid-Sensitive Encephalopathy Associated With Autoimmune Thyroiditis (SREAT): Case Report

Diego Nicolas Guacaneme, Claudio Alejando Jiménez Monsalve, Orlando Oliveros Pasión, Julieth Milena Rodríguez López, Neiry María Zapa Pérez, Hellen Kreinter, Nelly Daniela Gonzalez Galvis
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Abstract

Background: Steroid-responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT) is a rare, controversial and underdiagnosed entity characterized by an acute or subacute onset of encephalopathy. It is a diagnosis of exclusion with supporting criteria that include high titers of anti-thyroid antibodies, a history of Hashimoto's thyroiditis, and a good response to steroids. Case report: An 18-year-old female patient with hypothyroidism and episode of change in behavior, hallucinations and episodes of generalized tonic-clonic movements, normal skull tomography, cerebrospinal fluid with pleocytosis without signs of infection and positive anti-thyroid antibodies with adequate response to management with steroids Conclusion: We considered SERAT as an entity that needs to be rediscovered as it has conflicting results that question if it is a syndrome or a myth. The literature is especially lacking in Colombia where there are not many published cases.
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类固醇敏感性脑病与自身免疫性甲状腺炎(great):病例报告
背景:类固醇反应性脑病伴自身免疫性甲状腺炎(SREAT)是一种罕见的、有争议的、诊断不足的疾病,其特征是急性或亚急性发作的脑病。这是一种排除性诊断,支持标准包括抗甲状腺抗体高滴度,桥本甲状腺炎病史,类固醇反应良好。病例报告:一例18岁女性甲状腺功能减退患者,行为改变发作,幻觉和全身性强直-阵挛性运动发作,颅骨断层扫描正常,脑脊液伴多细胞增多,无感染迹象,抗甲状腺抗体阳性,类固醇治疗反应充分。结论:我们认为SERAT是一个需要重新发现的实体,因为它有相互矛盾的结果,质疑它是综合征还是神话。有关文献在哥伦比亚尤其缺乏,那里发表的病例并不多。
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