Human health implications of emerging diseases and the current situation in India's vaccine industry

Jiban Kumar Behera , Pabitra Mishra , Anway Kumar Jena , Bhaskar Behera , Manojit Bhattacharya
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Abstract

Emerging diseases are infectious diseases that pose significant threat to human health, causing millions of deaths and disabilities in the upcoming days. Periodic epidemics of new infections and old reinfections increase the global burden of disease prevalence. They can be caused by new pathogens or evolving ones, which change human behavior and environmental factors. Researchers have studied the dynamic connections between microbes, hosts, and the environment, but new infectious diseases like coronavirus disease 2019 (COVID-19), re-emerging diseases, and deliberately disseminated diseases persist despite earlier hopes of elimination. With heavy privatesector investments, Indian pharmacology now provides core Expanded Programme on Immunization vaccines to United Nations International Children's Emergency Fund, producing previously unattainable vaccines for diseases like meningitis, hepatitis B, pneumococcal conjugate, rotavirus, influenza A (H1N1), and COVID-19. India's vaccine sector has emerged, among the oriented leaders of the Bharat Biotech, Serum Institute of India, Panacea Biotech and Biological E. Specifically, the technology transferred from Western countries has benefited the sector, which produces 1.3 billion doses annually. The Serum Institute is the world's largest manufacturer of vaccines, providing measles and diphtheria-tetanus-pertussis vaccines to United Nations. The Serum Institute has developed several vaccines, including Nasovac, MenAfriVac, Pentavac, and an inactivated polio vaccine. India's success in vaccinations can be attributed to attractive investment conditions, government assistance, international alliances, and rising domestic technical talent. Despite its booming economy and technical advances, India's disproportionate share of the world's child mortality rate remains unchanged. However, the growing production and distribution of vaccinations in developing nations has initiated a new era, leading to a worldwide decline in childhood death and disease.

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新发疾病对人类健康的影响以及印度疫苗工业的现状
新发疾病是对人类健康构成重大威胁的传染病,在未来几天造成数百万人死亡和残疾。新发感染和旧发再感染的周期性流行增加了全球疾病流行的负担。它们可能是由新的病原体或进化的病原体引起的,这些病原体会改变人类的行为和环境因素。研究人员研究了微生物、宿主和环境之间的动态联系,但COVID-19等新传染病、重新出现的疾病和故意传播的疾病,尽管早期希望消除,但仍然存在。在私营部门的大量投资下,印度药物学现在向联合国儿童基金会提供核心扩大免疫方案疫苗,生产脑膜炎、乙型肝炎、肺炎球菌结合、轮状病毒、甲型H1N1流感和COVID-19等疾病以前无法获得的疫苗。印度的疫苗部门已经出现,其中包括巴拉特生物技术、印度血清研究所、万灵药生物技术和e生物公司。具体来说,来自西方的技术转让使该部门受益,该部门每年生产13亿剂疫苗。血清研究所是世界上最大的疫苗制造商,向联合国各组织提供麻疹和百白破疫苗。血清研究所开发了几种疫苗,包括Nasovac、MenAfriVac、Pentavac和一种灭活脊髓灰质炎疫苗。印度在疫苗接种方面的成功可归因于有吸引力的投资条件、政府援助、国际联盟和不断增长的国内技术人才。尽管经济蓬勃发展,技术进步,但印度在世界儿童死亡率中所占比例不成比例的情况仍未改变。然而,发展中国家不断增加的疫苗生产和分配开创了一个新时代,导致世界范围内儿童死亡和疾病的减少。
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