Screening of serum antibody to symptomatic and asymptomatic patients with Hymenolepis nana

Abstract

Hymenolepis nana is a common parasitic disease that spreads mainly to children. The present study aims to circulate anti-parasite antibody responses against H.nana in the symptomatic and asymptomatic IN children with assured hymenolepiasis examined in Al-Najaf province. Symptomatic patients were explicitly used as follows: the existence of H.nana eggs in the feces with more symptoms such as diarrhea, abdominal pain, losing weight, flatulency, appetite loss, and nausea. Antiparasite of the humoral immune response had been measured using indirect immunofluorescence (IFA) and ELISA. A significant disparity was noticed in the antiparasite antibody response when measuring the IFA of the asymptomatic and symptomatic patients. Over 37% of asymptomatic patients had a titer of 1:500 or lower, and more than 28% of symptomatic patients had a titer of 1:8000 or higher. When measured by ELISA, the circulation of anti-parasite overall IgM and IgA is significantly higher in symptomatic than asymptomatic patients, as regarding upper egg production showed in the symptomatic people. Keywords: Hymenolepis nana, Cysticercoids, asymptomatic and symptomatic patients, Antibody response.