Extracorporeal Shockwave Therapy Improves Outcomes Following Secondary Alveolar Bone Grafting

Demetrius M. Coombs, Viren Patel, Nicholas Kochenour, Niyant Patel, Ananth S. Murthy
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Abstract

Background: Recent studies have reported that extracorporeal shock wave therapy (ESWT) enhances bone formation during mandibular distraction osteogenesis. This study seeks to investigate the clinical outcomes in children undergoing ESWT alongside secondary alveolar bone grafting procedures at our institution. Methods: Retrospective review of all children that underwent secondary alveolar cleft bone grafting with adjunctive ESWT between 2019 and 2021. Variables including age, gender, cleft type, cleft width, pre-operative cleft dentition, volume of bone graft placed intraoperatively, ESWT settings, pain medication utilization, length of stay (LOS), follow-up, cone beam computed tomography (CBCT) data, and complications were recorded. Results: Twenty patients met inclusion criteria. Median age at surgery was 9 years (range 8-16). Four (20%) patients were female; 16 (80%) were male. Eight (40%) patients had bilateral alveolar clefts; 12 (60%) had unilateral clefts. All (100%) patients were discharged on the day of surgery. Twelve (60%) patients required a median of 1.3 oxycodone doses post-operatively (range 0-6.5). All patients received ESWT treatments intra and post-operatively. All patients demonstrated an increase in bone graft volume visualized on CBCT: median increase of 6.8% (range 1.3%-35.7%) between 106.5 days (17.5% of ideal visualized, range 5%-42%) and 245.5 days (27.9% of ideal, range 8%-55.7%). Three (15%) patients experienced minor complications. Conclusions: Initial outcomes suggest that ESWT may expedite visualization of bone consolidation and facilitate recovery without increasing complications. ESWT could further represent an opportunity to improve care in craniofacial surgery. Pertinent considerations, the role of standardized assessment protocols, and future directions will be reviewed.
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体外冲击波治疗改善继发性牙槽骨移植后的预后
背景:最近的研究报道了体外冲击波治疗(ESWT)促进下颌骨牵张成骨过程中的骨形成。本研究旨在调查在我院接受ESWT和二次牙槽骨移植手术的儿童的临床结果。方法:回顾性分析2019年至2021年间所有接受辅助ESWT继发性牙槽裂植骨的儿童。变量包括年龄、性别、唇裂类型、唇裂宽度、术前牙列、术中植骨体积、ESWT设置、止痛药使用、住院时间(LOS)、随访、锥形束计算机断层扫描(CBCT)数据和并发症。结果:20例患者符合纳入标准。手术年龄中位数为9岁(范围8-16岁)。女性4例(20%);男性16例(80%)。8例(40%)患者有双侧牙槽裂;12例(60%)单侧唇裂。所有(100%)患者均于手术当日出院。12例(60%)患者术后需要平均1.3剂量的羟考酮(范围0-6.5)。所有患者均在术中及术后接受ESWT治疗。所有患者在CBCT上显示植骨体积增加:在106.5天(17.5%理想显示,范围5%-42%)和245.5天(27.9%理想显示,范围8%-55.7%)期间,中位增加6.8%(范围1.3%-35.7%)。3例(15%)患者出现轻微并发症。结论:初步结果表明,ESWT可以加速骨巩固的可视化并促进恢复,而不会增加并发症。ESWT可以进一步代表一个改善颅面外科护理的机会。将审查有关的考虑、标准化评估协议的作用和今后的方向。
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