首页 > 最新文献

FACE (Thousand Oaks, Calif.)最新文献

英文 中文
Rock, Paper, Scissors. . .and Plastic? 石头、剪刀、布……还有塑料?
Pub Date : 2023-11-10 DOI: 10.1177/27325016231206597
John van Aalst
{"title":"Rock, Paper, Scissors. . .and Plastic?","authors":"John van Aalst","doi":"10.1177/27325016231206597","DOIUrl":"https://doi.org/10.1177/27325016231206597","url":null,"abstract":"","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135185939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Epidemiology of Facial Injury on the Far Side of the COVID-19 Pandemic Curve: What Happened After the Repeal of Social Distancing Laws? 在COVID-19大流行曲线的另一端,面部损伤的流行病学:废除社交距离法后发生了什么?
Pub Date : 2023-11-06 DOI: 10.1177/27325016231209403
Gary R. Hoffman, Sophie K. M. Kelly, Hao-Hsuan (Mark) Tsai
Background: In response to the COVID-19 outbreak, the widespread imposition of social distancing and lockdown orders had an unintended secondary effect on reducing and changing the characteristics of facial injury presentations to tertiary referral hospitals. As the pandemic curve plateaued and indeed fell, these restrictions were periodically repealed, engendering an anticipated rise in the frequency facial injuries. Objective: The purpose of this study was to determine whether the frequency and characteristics of facial injury presentations to our tertiary referral hospital returned to pre-COVID levels following the repeal of COVID-19 social distancing and lockdown laws on the far side of the pandemic curve. Methods: The authors designed and implemented a retrospective study of patients who sustained a facial injury over 3 comparable 8-week periods in 2019 (pre-COVID), 2020 (COVID lockdown) and 2023 (post-repeal of COVID lockdown laws). The study was conducted in the Department of Maxillofacial Surgery at a level 1 tertiary referral regional trauma hospital in Newcastle, Australia. Results: The principal finding was an increase in facial injury frequency in the post-COVID cohort (n = 149), compared to the COVID lockdown (n = 37) and pre-COVID groups (n = 103). Across all 3 periods, males consistently outnumbered females, with a common peak in the 20 to 30 age group. Bony injuries predominated in all cohorts, with no difference in management approach. The leading cause of injury pre-COVID was interpersonal violence, which shifted to falls during lockdown and post-COVID. There was also an increase in workplace and animal-related injuries post-COVID. Conclusion: The frequency and characteristics of facial injury presentation finally stabilized and returned to pre-COVID levels following the repeal of social distancing laws. This was most notable as communities entered the far side of the pandemic curve. The findings are in keeping with a very small number of comparable studies sourced from literature.
背景:为应对COVID-19疫情,广泛实施的社交距离和封锁令对减少和改变三级转诊医院面部损伤的特征产生了意想不到的次要影响。随着大流行曲线趋于稳定并确实下降,这些限制定期被废除,导致预期面部受伤频率上升。目的:本研究的目的是确定在大流行曲线远端的COVID-19社交距离和封锁法律废除后,我们三级转诊医院的面部损伤就诊频率和特征是否恢复到COVID-19前的水平。方法:作者设计并实施了一项回顾性研究,研究对象是2019年(COVID - 19前)、2020年(COVID - 19封锁)和2023年(COVID - 19封锁法废除后)3个可比较的8周期间遭受面部损伤的患者。这项研究是在澳大利亚纽卡斯尔一家三级转诊区域创伤医院的颌面外科进行的。结果:主要发现是,与COVID封锁组(n = 37)和COVID前组(n = 103)相比,COVID后队列(n = 149)的面部损伤频率有所增加。在这三个时期,男性的数量一直超过女性,在20至30岁年龄组中达到高峰。骨损伤在所有队列中都占主导地位,治疗方法没有差异。在疫情前,造成伤害的主要原因是人际暴力,在封锁期间和疫情后,这一原因转向了跌倒。新冠肺炎后,与工作场所和动物有关的伤害也有所增加。结论:随着社交距离法的废除,面部损伤的出现频率和特征最终趋于稳定,并恢复到疫情前的水平。随着社区进入大流行曲线的远端,这一点尤为明显。这些发现与来自文献的极少数可比研究相一致。
{"title":"The Epidemiology of Facial Injury on the Far Side of the COVID-19 Pandemic Curve: What Happened After the Repeal of Social Distancing Laws?","authors":"Gary R. Hoffman, Sophie K. M. Kelly, Hao-Hsuan (Mark) Tsai","doi":"10.1177/27325016231209403","DOIUrl":"https://doi.org/10.1177/27325016231209403","url":null,"abstract":"Background: In response to the COVID-19 outbreak, the widespread imposition of social distancing and lockdown orders had an unintended secondary effect on reducing and changing the characteristics of facial injury presentations to tertiary referral hospitals. As the pandemic curve plateaued and indeed fell, these restrictions were periodically repealed, engendering an anticipated rise in the frequency facial injuries. Objective: The purpose of this study was to determine whether the frequency and characteristics of facial injury presentations to our tertiary referral hospital returned to pre-COVID levels following the repeal of COVID-19 social distancing and lockdown laws on the far side of the pandemic curve. Methods: The authors designed and implemented a retrospective study of patients who sustained a facial injury over 3 comparable 8-week periods in 2019 (pre-COVID), 2020 (COVID lockdown) and 2023 (post-repeal of COVID lockdown laws). The study was conducted in the Department of Maxillofacial Surgery at a level 1 tertiary referral regional trauma hospital in Newcastle, Australia. Results: The principal finding was an increase in facial injury frequency in the post-COVID cohort (n = 149), compared to the COVID lockdown (n = 37) and pre-COVID groups (n = 103). Across all 3 periods, males consistently outnumbered females, with a common peak in the 20 to 30 age group. Bony injuries predominated in all cohorts, with no difference in management approach. The leading cause of injury pre-COVID was interpersonal violence, which shifted to falls during lockdown and post-COVID. There was also an increase in workplace and animal-related injuries post-COVID. Conclusion: The frequency and characteristics of facial injury presentation finally stabilized and returned to pre-COVID levels following the repeal of social distancing laws. This was most notable as communities entered the far side of the pandemic curve. The findings are in keeping with a very small number of comparable studies sourced from literature.","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135680493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are Patients With Syndromic Craniosynostosis at Greater Risk for Abnormal Speech and Language Development Than Patients With Non-syndromic Craniosynostosis? 综合征性颅缝闭闭患者比非综合征性颅缝闭闭患者言语和语言发育异常的风险更大吗?
Pub Date : 2023-10-31 DOI: 10.1177/27325016231206824
Dani Stanbouly, Fereshteh Goudarzi, Ricardo Grillo, Jeffrey A. Ascherman, Brian Kinard, James C. Melville
Objective: The aim of this study was to determine whether patients with syndromic craniosynostosis (SCS) are at increased risk for abnormal speech and language development (ASLD) relative to patients with non-syndromic craniosynostosis (NSCS). Study Design: A retrospective cohort study was completed using the Kids’ Inpatient Database (KID). All patients with craniosynostosis (CS) were included were included. The primary predictor variable was study grouping (SCS vs NSCS). The primary outcome variable was ASLD. Multivariate logistic regression were performed to identify risk factors for ASLD. Results: The final study sample included a total of 10 089 patients with craniosynostosis (CS) (37.7% female, 51.6% White, mean age 1.78 years). Patients with SCS were at increased risk for ASLD relative to patients with NSCS (OR 2.1, P < .001). After controlling for all other variables, patients with SCS were no longer at increased risk for ASLD relative to patients with NSCS (OR 1.2, P = .442). Conclusions: Relative to NSCS, SCS per se is not a risk factor for ASLD. The significantly greater prevalence of asthma, intracranial hypertension, and compression of brain, all of which are risk factors for ASLD, among patients with SCS explains the greater prevalence of ASLD in SCS relative to NSCS.
目的:本研究的目的是确定综合征性颅缝闭闭(SCS)患者相对于非综合征性颅缝闭闭(NSCS)患者是否有更高的言语和语言发育异常(ASLD)风险。研究设计:使用儿童住院患者数据库(KID)完成回顾性队列研究。所有颅缝闭合(CS)患者均被纳入。主要预测变量为研究分组(SCS vs NSCS)。主要结局变量为ASLD。采用多因素logistic回归来确定ASLD的危险因素。结果:最终的研究样本包括1089例颅缝闭闭(CS)患者(女性37.7%,白人51.6%,平均年龄1.78岁)。与NSCS患者相比,SCS患者发生ASLD的风险增加(OR 2.1, P <措施)。在控制了所有其他变量后,SCS患者与NSCS患者相比,ASLD的风险不再增加(OR 1.2, P = .442)。结论:相对于NSCS, SCS本身不是ASLD的危险因素。在SCS患者中,哮喘、颅内高压和脑压迫的患病率明显高于ASLD,这些都是ASLD的危险因素,这解释了相对于NSCS, SCS中ASLD的患病率更高。
{"title":"Are Patients With Syndromic Craniosynostosis at Greater Risk for Abnormal Speech and Language Development Than Patients With Non-syndromic Craniosynostosis?","authors":"Dani Stanbouly, Fereshteh Goudarzi, Ricardo Grillo, Jeffrey A. Ascherman, Brian Kinard, James C. Melville","doi":"10.1177/27325016231206824","DOIUrl":"https://doi.org/10.1177/27325016231206824","url":null,"abstract":"Objective: The aim of this study was to determine whether patients with syndromic craniosynostosis (SCS) are at increased risk for abnormal speech and language development (ASLD) relative to patients with non-syndromic craniosynostosis (NSCS). Study Design: A retrospective cohort study was completed using the Kids’ Inpatient Database (KID). All patients with craniosynostosis (CS) were included were included. The primary predictor variable was study grouping (SCS vs NSCS). The primary outcome variable was ASLD. Multivariate logistic regression were performed to identify risk factors for ASLD. Results: The final study sample included a total of 10 089 patients with craniosynostosis (CS) (37.7% female, 51.6% White, mean age 1.78 years). Patients with SCS were at increased risk for ASLD relative to patients with NSCS (OR 2.1, P < .001). After controlling for all other variables, patients with SCS were no longer at increased risk for ASLD relative to patients with NSCS (OR 1.2, P = .442). Conclusions: Relative to NSCS, SCS per se is not a risk factor for ASLD. The significantly greater prevalence of asthma, intracranial hypertension, and compression of brain, all of which are risk factors for ASLD, among patients with SCS explains the greater prevalence of ASLD in SCS relative to NSCS.","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135871279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MRI Modeling for 3D Printed Fabrication of Nasoalveolar Molding Appliance in Patients With Cleft Lip and Palate 唇腭裂患者鼻牙槽成型器3D打印的MRI建模
Pub Date : 2023-10-26 DOI: 10.1177/27325016231208381
Chelsea L. Wehr, Austin Lignieres, Chioma G. Obinero, Alfredo Cepeda, Antonio Cardenas, F. Kurtis Kasper, Bhavini Acharya, Eliana Bonfante-Mejia, Roy Riascos-Castaneda, Rajan Patel, Brett T. Chiquet, Matthew R. Greives
Purpose: Present a novel technique for fabrication of nasoalveolar molding (NAM) appliances for neonates with cleft lip and palate (CLP) using magnetic resonance imaging (MRI). Study design: Proof-of-concept study. Setting/Participants: One patient with unilateral CLP was recruited for participation in this study at our institution. Interventions: This study employed 2 different methods for creating a NAM appliance, which is used in patients with CLP to improve anatomic positioning of the orofacial cleft in preparation for primary cheiloplasty. The patient underwent intraoral impression for traditional fabrication of a NAM appliance (PMMA-NAM) and also MRI of the face for digital fabrication of a NAM appliance (CAD-NAM). The 2 appliances were then compared using landmarks for measurements. Primary Outcome: Landmark measurements on NAM appliances; Clinical interchangeability of NAM appliances. Results: There was a statistically significant difference in the external arch width between the CAD-NAM and the PMMA-NAM. All other NAM measurements were statistically similar. Additionally, there was clinical success in the interchangeable fit of both appliances on both models. Conclusions: This technique could potentially eliminate the need for creation of an intraoral impression, as well as the adverse events associated with this, in the fabrication of NAM appliances. Larger studies are necessary to further define the efficacy of this novel approach and generalizability to other patients with CLP.
目的:介绍一种利用磁共振成像(MRI)制作新生儿唇腭裂(CLP)鼻肺泡成型(NAM)矫治器的新技术。研究设计:概念验证研究。环境/参与者:我们机构招募了一名单侧CLP患者参加本研究。干预措施:本研究采用两种不同的方法制作NAM矫治器,用于CLP患者改善口面裂的解剖定位,为初次唇腭裂成形术做准备。患者接受了口腔内印模,用于传统的NAM矫治器制作(PMMA-NAM),并进行了面部MRI,用于数字制作NAM矫治器(CAD-NAM)。然后用地标测量比较这两种器具。主要结果:不结盟运动器具的里程碑测量;NAM器械的临床互换性。结果:CAD-NAM与PMMA-NAM的外弓宽度差异有统计学意义。所有其他NAM测量在统计上是相似的。此外,在两种型号上的两种器具的可互换配合方面取得了临床成功。结论:该技术可以潜在地消除制造口腔内印模的需要,以及在制造NAM矫治器时与之相关的不良事件。需要更大规模的研究来进一步确定这种新方法的疗效和推广到其他CLP患者。
{"title":"MRI Modeling for 3D Printed Fabrication of Nasoalveolar Molding Appliance in Patients With Cleft Lip and Palate","authors":"Chelsea L. Wehr, Austin Lignieres, Chioma G. Obinero, Alfredo Cepeda, Antonio Cardenas, F. Kurtis Kasper, Bhavini Acharya, Eliana Bonfante-Mejia, Roy Riascos-Castaneda, Rajan Patel, Brett T. Chiquet, Matthew R. Greives","doi":"10.1177/27325016231208381","DOIUrl":"https://doi.org/10.1177/27325016231208381","url":null,"abstract":"Purpose: Present a novel technique for fabrication of nasoalveolar molding (NAM) appliances for neonates with cleft lip and palate (CLP) using magnetic resonance imaging (MRI). Study design: Proof-of-concept study. Setting/Participants: One patient with unilateral CLP was recruited for participation in this study at our institution. Interventions: This study employed 2 different methods for creating a NAM appliance, which is used in patients with CLP to improve anatomic positioning of the orofacial cleft in preparation for primary cheiloplasty. The patient underwent intraoral impression for traditional fabrication of a NAM appliance (PMMA-NAM) and also MRI of the face for digital fabrication of a NAM appliance (CAD-NAM). The 2 appliances were then compared using landmarks for measurements. Primary Outcome: Landmark measurements on NAM appliances; Clinical interchangeability of NAM appliances. Results: There was a statistically significant difference in the external arch width between the CAD-NAM and the PMMA-NAM. All other NAM measurements were statistically similar. Additionally, there was clinical success in the interchangeable fit of both appliances on both models. Conclusions: This technique could potentially eliminate the need for creation of an intraoral impression, as well as the adverse events associated with this, in the fabrication of NAM appliances. Larger studies are necessary to further define the efficacy of this novel approach and generalizability to other patients with CLP.","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134909268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socioeconomic Disparities in Failure to Thrive and Weight Gain for Patients With Cleft Lip and Palate 唇腭裂患者发育不良和体重增加的社会经济差异
Pub Date : 2023-10-26 DOI: 10.1177/27325016231203517
Dillan F. Villavisanis, Carrie Z. Morales, Connor S. Wagner, Jessica D. Blum, Nancy Folsom, Daniel Y. Cho, Scott P. Bartlett, Jesse A. Taylor, Jordan W. Swanson
Background: Given the relatively resource-intensive burden of treating orofacial clefting and its functional and aesthetic sequelae, it is perhaps unsurprising that lower socioeconomic status is known to have adverse effects on outcomes in patients with cleft lip and/or palate (CL/P). Although outcomes in patients with CL/P are known to be influenced by socioeconomic status, the relationship between socioeconomic status and age-related weight gain has not been described. This study aimed to determine time-specific socioeconomic disparities in weight-for-age Z-scores and failure to thrive in patients with CL/P. Methods: This retrospective study evaluated patients presenting with CL/P from 2009 to 2019 at a tertiary children’s hospital. Failure to thrive status was determined by weight-for-age Z-scores less than −2.00 (second percentile) or from the EHR. Median income by block group was determined from US 2019 census data. Results: Multivariate linear regression models controlled for syndromic status, sex, and race revealed significant associations between median block group income and weight-for-age Z-scores at 4 weeks (β = .14, P = .009), 6 weeks (β = .15, P = .003), and 8 weeks (β = .14, P = .002). Mann Whitney U tests revealed significantly different weight-for-age Z-scores between low-income and high-income groups at 4 weeks ( P = .002), 6 weeks ( P < .001), 8 weeks ( P < .001), 10 weeks ( P = .005), and 12 weeks ( P = .004). Conclusions: Patients with CL/P and lower socioeconomic status may be most susceptible to disparities in weight gain between 4 and 8 weeks of age. Lower socioeconomic status was an independent predictor of failure to thrive for patients with CL/P in this cohort. This study highlights a welcome opportunity for timed intervention in patients with CL/P and lower socioeconomic status.
背景:考虑到治疗唇腭裂的相对资源密集型负担及其功能和美学后遗症,较低的社会经济地位对唇裂和/或腭裂(CL/P)患者的预后有不利影响,这可能不足为奇。虽然已知CL/P患者的预后受社会经济地位的影响,但社会经济地位与年龄相关体重增加之间的关系尚未得到描述。本研究旨在确定CL/P患者在年龄体重z分数和成长失败方面的时间特异性社会经济差异。方法:本回顾性研究评估了一家三级儿童医院2009年至2019年出现CL/P的患者。未能茁壮成长的状态由年龄体重z分数小于- 2.00(第二个百分位数)或EHR确定。按街区组划分的收入中位数是根据美国2019年人口普查数据确定的。结果:控制综合症状态、性别和种族的多元线性回归模型显示,在4周(β = .14, P = .009)、6周(β = .15, P = .003)和8周(β = .14, P = .002)时,中位块组收入和年龄体重z分数之间存在显著关联。Mann Whitney U检验显示,低收入组和高收入组在第4周(P = 0.002)、第6周(P <.001), 8周(P <0.001)、10周(P = 0.005)和12周(P = 0.004)。结论:CL/P患者和社会经济地位较低的患者可能最容易在4到8周龄之间出现体重增加差异。较低的社会经济地位是本队列中CL/P患者生存失败的独立预测因子。本研究强调了对社会经济地位较低的CL/P患者进行定时干预的一个受欢迎的机会。
{"title":"Socioeconomic Disparities in Failure to Thrive and Weight Gain for Patients With Cleft Lip and Palate","authors":"Dillan F. Villavisanis, Carrie Z. Morales, Connor S. Wagner, Jessica D. Blum, Nancy Folsom, Daniel Y. Cho, Scott P. Bartlett, Jesse A. Taylor, Jordan W. Swanson","doi":"10.1177/27325016231203517","DOIUrl":"https://doi.org/10.1177/27325016231203517","url":null,"abstract":"Background: Given the relatively resource-intensive burden of treating orofacial clefting and its functional and aesthetic sequelae, it is perhaps unsurprising that lower socioeconomic status is known to have adverse effects on outcomes in patients with cleft lip and/or palate (CL/P). Although outcomes in patients with CL/P are known to be influenced by socioeconomic status, the relationship between socioeconomic status and age-related weight gain has not been described. This study aimed to determine time-specific socioeconomic disparities in weight-for-age Z-scores and failure to thrive in patients with CL/P. Methods: This retrospective study evaluated patients presenting with CL/P from 2009 to 2019 at a tertiary children’s hospital. Failure to thrive status was determined by weight-for-age Z-scores less than −2.00 (second percentile) or from the EHR. Median income by block group was determined from US 2019 census data. Results: Multivariate linear regression models controlled for syndromic status, sex, and race revealed significant associations between median block group income and weight-for-age Z-scores at 4 weeks (β = .14, P = .009), 6 weeks (β = .15, P = .003), and 8 weeks (β = .14, P = .002). Mann Whitney U tests revealed significantly different weight-for-age Z-scores between low-income and high-income groups at 4 weeks ( P = .002), 6 weeks ( P < .001), 8 weeks ( P < .001), 10 weeks ( P = .005), and 12 weeks ( P = .004). Conclusions: Patients with CL/P and lower socioeconomic status may be most susceptible to disparities in weight gain between 4 and 8 weeks of age. Lower socioeconomic status was an independent predictor of failure to thrive for patients with CL/P in this cohort. This study highlights a welcome opportunity for timed intervention in patients with CL/P and lower socioeconomic status.","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134908803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of rhBMP-2 and Cellular Bone Matrix in the Revision of Alveolar Bone Grafting rhBMP-2与细胞骨基质改良牙槽骨移植的疗效观察
Pub Date : 2023-10-23 DOI: 10.1177/27325016231206793
Lucas M. Harrison, Rami R. Hallac, James R. Seaward, Alex A. Kane, Yong Jong Park
Objective: This study presents a novel approach that utilizes recombinant human bone morphogenic protein 2 (rhBMP-2) and cellular bone matrix (CBM) for revision alveolar bone graft (ABG) in unilateral cleft lip and palate (UCLP) and bilateral cleft lip and palate (BCLP) patients following failed autologous ABG. Methods: A case series of 14 UCLP and 4 BCLP patients who had failed autologous ABG with revision ABG with rhBMP-2 and CBM. Review of demographics, operative data, Bergland score, and alveolar cleft gap volume was performed. Results: Revision ABG had short operative times and low blood loss in both UCLP and BCLP. No postoperative complications were found in either revision group. Repeat ABG surgery was required in one patient. Bergland score improved from 3.86 ± 0.53to 1.21 ± 0.80 in the UCLP group and from 3.75 ± 0.50to 1.00 ± 0.00 in the BCLP group. The cleft volume decreased by 83.62 ± 9.78% in UCLP and by 86.73 ± 13.65% in the BCLP group. Conclusions: Revision ABG with rhBMP-2 and CBM is a successful and reliable approach. This method has decreased operative time and no postoperative complications. Most patients achieved clinically successful grafting with canine eruption. Both UCLP and BCLP groups saw a significant decrease in alveolar cleft gap volume.
目的:提出一种利用重组人骨形态发生蛋白2 (rhBMP-2)和细胞骨基质(CBM)进行单侧唇腭裂(UCLP)和双侧唇腭裂(BCLP)患者自体唇腭裂(ABG)术后修复牙槽骨移植(ABG)的新方法。方法:对14例UCLP和4例BCLP患者进行自体ABG失败,并采用rhBMP-2和CBM进行改良ABG。回顾人口统计学、手术数据、Bergland评分和牙槽裂间隙容积。结果:改良ABG在UCLP和BCLP中手术时间短,出血量少。两组均未见术后并发症。1例患者需要重复ABG手术。UCLP组的Bergland评分从3.86±0.53提高到1.21±0.80,BCLP组从3.75±0.50提高到1.00±0.00。UCLP组和BCLP组的裂隙体积分别减少83.62±9.78%和86.73±13.65%。结论:结合rhBMP-2和CBM的改良ABG是一种成功可靠的方法。该方法缩短了手术时间,无术后并发症。大多数患者临床成功移植犬疹。UCLP组和BCLP组牙槽间隙体积均明显减小。
{"title":"Efficacy of rhBMP-2 and Cellular Bone Matrix in the Revision of Alveolar Bone Grafting","authors":"Lucas M. Harrison, Rami R. Hallac, James R. Seaward, Alex A. Kane, Yong Jong Park","doi":"10.1177/27325016231206793","DOIUrl":"https://doi.org/10.1177/27325016231206793","url":null,"abstract":"Objective: This study presents a novel approach that utilizes recombinant human bone morphogenic protein 2 (rhBMP-2) and cellular bone matrix (CBM) for revision alveolar bone graft (ABG) in unilateral cleft lip and palate (UCLP) and bilateral cleft lip and palate (BCLP) patients following failed autologous ABG. Methods: A case series of 14 UCLP and 4 BCLP patients who had failed autologous ABG with revision ABG with rhBMP-2 and CBM. Review of demographics, operative data, Bergland score, and alveolar cleft gap volume was performed. Results: Revision ABG had short operative times and low blood loss in both UCLP and BCLP. No postoperative complications were found in either revision group. Repeat ABG surgery was required in one patient. Bergland score improved from 3.86 ± 0.53to 1.21 ± 0.80 in the UCLP group and from 3.75 ± 0.50to 1.00 ± 0.00 in the BCLP group. The cleft volume decreased by 83.62 ± 9.78% in UCLP and by 86.73 ± 13.65% in the BCLP group. Conclusions: Revision ABG with rhBMP-2 and CBM is a successful and reliable approach. This method has decreased operative time and no postoperative complications. Most patients achieved clinically successful grafting with canine eruption. Both UCLP and BCLP groups saw a significant decrease in alveolar cleft gap volume.","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135413449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating Tranexamic Acid Administration in Cranial Vault Reconstruction: The Experience of an Academic Center in the Deep South 评价氨甲环酸在颅拱顶重建中的应用:深南方某学术中心的经验
Pub Date : 2023-10-18 DOI: 10.1177/27325016231206114
Edgar Soto, James Johnston, Krista Niedermeier, Ann Carol Braswell, Curtis J. Rozelle, John H. Grant, Rene P. Myers
Background: In infants with craniosynostosis, cranial vault reconstruction is performed to prevent sequela of premature fusion of cranial sutures. Open correction puts patients at risk for complications of major blood loss. We evaluated the impact of tranexamic acid (TXA) in children undergoing open surgical repair of a variety of types of craniosynostosis. Methods: A retrospective review of 102 infants who underwent open cranial vault reconstruction between January 2015 and December 2020 at a tertiary referral hospital was performed. The patients were stratified into TXA or non-TXA based on usage. Outcome measures included volume of blood transfused, perioperative blood loss and any adverse effects were noted. Results: In this cohort 42% of patients were treated with TXA. There was no significant difference between the patient demographics of TXA and non-TXA cohorts with the majority classified as Sagittal Craniosynostosis ( P = .1062), an average weight of 8.89 ± 1.37 kg, and age of 9.02 ± 2.02 months at time of surgery. The non-TXA cohort had longer length of hospital stay ( P = .04). The TXA cohort had an average 100 ml decrease in surgical drain output over the course of their hospital stay ( P = .02). Overall surgical complication was 14% ( P = .18) and clinical outcomes were not significantly different between the cohorts. Conclusions: The receipt of TXA in the interoperative period in patients with craniosynostosis undergoing cranial vault remodeling was associated with a decreased surgical drain output and length of stay.
背景:对于颅缝闭合的婴儿,颅拱顶重建是为了防止颅缝过早融合的后遗症。开放式矫正会使患者面临大出血并发症的风险。我们评估了氨甲环酸(TXA)对接受开放性手术修复各种类型颅缝闭锁的儿童的影响。方法:回顾性分析2015年1月至2020年12月在某三级转诊医院接受开放颅拱顶重建的102例婴儿。根据使用情况将患者分为TXA和非TXA两组。结果测量包括输血量、围手术期失血量和任何不良反应。结果:在该队列中,42%的患者接受了TXA治疗。TXA组与非TXA组的患者人口统计学差异无统计学意义(P = 0.1062),其中大多数为矢状颅缝闭塞,平均体重为8.89±1.37 kg,手术时年龄为9.02±2.02个月。非txa组患者住院时间较长(P = 0.04)。TXA组在住院期间平均减少了100毫升的手术引流液(P = 0.02)。总手术并发症为14% (P = 0.18),临床结果在队列之间无显著差异。结论:颅缝闭锁行颅拱顶重塑的患者在手术期间接受TXA与手术引流量和住院时间的减少有关。
{"title":"Evaluating Tranexamic Acid Administration in Cranial Vault Reconstruction: The Experience of an Academic Center in the Deep South","authors":"Edgar Soto, James Johnston, Krista Niedermeier, Ann Carol Braswell, Curtis J. Rozelle, John H. Grant, Rene P. Myers","doi":"10.1177/27325016231206114","DOIUrl":"https://doi.org/10.1177/27325016231206114","url":null,"abstract":"Background: In infants with craniosynostosis, cranial vault reconstruction is performed to prevent sequela of premature fusion of cranial sutures. Open correction puts patients at risk for complications of major blood loss. We evaluated the impact of tranexamic acid (TXA) in children undergoing open surgical repair of a variety of types of craniosynostosis. Methods: A retrospective review of 102 infants who underwent open cranial vault reconstruction between January 2015 and December 2020 at a tertiary referral hospital was performed. The patients were stratified into TXA or non-TXA based on usage. Outcome measures included volume of blood transfused, perioperative blood loss and any adverse effects were noted. Results: In this cohort 42% of patients were treated with TXA. There was no significant difference between the patient demographics of TXA and non-TXA cohorts with the majority classified as Sagittal Craniosynostosis ( P = .1062), an average weight of 8.89 ± 1.37 kg, and age of 9.02 ± 2.02 months at time of surgery. The non-TXA cohort had longer length of hospital stay ( P = .04). The TXA cohort had an average 100 ml decrease in surgical drain output over the course of their hospital stay ( P = .02). Overall surgical complication was 14% ( P = .18) and clinical outcomes were not significantly different between the cohorts. Conclusions: The receipt of TXA in the interoperative period in patients with craniosynostosis undergoing cranial vault remodeling was associated with a decreased surgical drain output and length of stay.","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135890071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Craniomaxillofacial abstracts presented at the 20th Congress of the International Society of Craniofacial Surgeons 在第20届国际颅面外科学会大会上发表的颅颌面摘要
Pub Date : 2023-10-16 DOI: 10.1177/27325016231206596
Restricted accessAbstractFirst published online October 16, 2023Craniomaxillofacial abstracts presented at the 20th Congress of the International Society of Craniofacial SurgeonsOnlineFirsthttps://doi.org/10.1177/27325016231206596
首次在线发表于2023年10月16日第20届国际颅面外科学会大会颅颌面摘要发表于sonlinefirst . http://doi.org/10.1177/27325016231206596
{"title":"Craniomaxillofacial abstracts presented at the 20<sup>th</sup> Congress of the International Society of Craniofacial Surgeons","authors":"","doi":"10.1177/27325016231206596","DOIUrl":"https://doi.org/10.1177/27325016231206596","url":null,"abstract":"Restricted accessAbstractFirst published online October 16, 2023Craniomaxillofacial abstracts presented at the 20th Congress of the International Society of Craniofacial SurgeonsOnlineFirsthttps://doi.org/10.1177/27325016231206596","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136113414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Future of Craniofacial Surgery 颅面外科的未来
Pub Date : 2023-10-16 DOI: 10.1177/27325016231206527
Jack C. Yu
{"title":"The Future of Craniofacial Surgery","authors":"Jack C. Yu","doi":"10.1177/27325016231206527","DOIUrl":"https://doi.org/10.1177/27325016231206527","url":null,"abstract":"","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136142239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracorporeal Shockwave Therapy Improves Outcomes Following Secondary Alveolar Bone Grafting 体外冲击波治疗改善继发性牙槽骨移植后的预后
Pub Date : 2023-10-11 DOI: 10.1177/27325016231203654
Demetrius M. Coombs, Viren Patel, Nicholas Kochenour, Niyant Patel, Ananth S. Murthy
Background: Recent studies have reported that extracorporeal shock wave therapy (ESWT) enhances bone formation during mandibular distraction osteogenesis. This study seeks to investigate the clinical outcomes in children undergoing ESWT alongside secondary alveolar bone grafting procedures at our institution. Methods: Retrospective review of all children that underwent secondary alveolar cleft bone grafting with adjunctive ESWT between 2019 and 2021. Variables including age, gender, cleft type, cleft width, pre-operative cleft dentition, volume of bone graft placed intraoperatively, ESWT settings, pain medication utilization, length of stay (LOS), follow-up, cone beam computed tomography (CBCT) data, and complications were recorded. Results: Twenty patients met inclusion criteria. Median age at surgery was 9 years (range 8-16). Four (20%) patients were female; 16 (80%) were male. Eight (40%) patients had bilateral alveolar clefts; 12 (60%) had unilateral clefts. All (100%) patients were discharged on the day of surgery. Twelve (60%) patients required a median of 1.3 oxycodone doses post-operatively (range 0-6.5). All patients received ESWT treatments intra and post-operatively. All patients demonstrated an increase in bone graft volume visualized on CBCT: median increase of 6.8% (range 1.3%-35.7%) between 106.5 days (17.5% of ideal visualized, range 5%-42%) and 245.5 days (27.9% of ideal, range 8%-55.7%). Three (15%) patients experienced minor complications. Conclusions: Initial outcomes suggest that ESWT may expedite visualization of bone consolidation and facilitate recovery without increasing complications. ESWT could further represent an opportunity to improve care in craniofacial surgery. Pertinent considerations, the role of standardized assessment protocols, and future directions will be reviewed.
背景:最近的研究报道了体外冲击波治疗(ESWT)促进下颌骨牵张成骨过程中的骨形成。本研究旨在调查在我院接受ESWT和二次牙槽骨移植手术的儿童的临床结果。方法:回顾性分析2019年至2021年间所有接受辅助ESWT继发性牙槽裂植骨的儿童。变量包括年龄、性别、唇裂类型、唇裂宽度、术前牙列、术中植骨体积、ESWT设置、止痛药使用、住院时间(LOS)、随访、锥形束计算机断层扫描(CBCT)数据和并发症。结果:20例患者符合纳入标准。手术年龄中位数为9岁(范围8-16岁)。女性4例(20%);男性16例(80%)。8例(40%)患者有双侧牙槽裂;12例(60%)单侧唇裂。所有(100%)患者均于手术当日出院。12例(60%)患者术后需要平均1.3剂量的羟考酮(范围0-6.5)。所有患者均在术中及术后接受ESWT治疗。所有患者在CBCT上显示植骨体积增加:在106.5天(17.5%理想显示,范围5%-42%)和245.5天(27.9%理想显示,范围8%-55.7%)期间,中位增加6.8%(范围1.3%-35.7%)。3例(15%)患者出现轻微并发症。结论:初步结果表明,ESWT可以加速骨巩固的可视化并促进恢复,而不会增加并发症。ESWT可以进一步代表一个改善颅面外科护理的机会。将审查有关的考虑、标准化评估协议的作用和今后的方向。
{"title":"Extracorporeal Shockwave Therapy Improves Outcomes Following Secondary Alveolar Bone Grafting","authors":"Demetrius M. Coombs, Viren Patel, Nicholas Kochenour, Niyant Patel, Ananth S. Murthy","doi":"10.1177/27325016231203654","DOIUrl":"https://doi.org/10.1177/27325016231203654","url":null,"abstract":"Background: Recent studies have reported that extracorporeal shock wave therapy (ESWT) enhances bone formation during mandibular distraction osteogenesis. This study seeks to investigate the clinical outcomes in children undergoing ESWT alongside secondary alveolar bone grafting procedures at our institution. Methods: Retrospective review of all children that underwent secondary alveolar cleft bone grafting with adjunctive ESWT between 2019 and 2021. Variables including age, gender, cleft type, cleft width, pre-operative cleft dentition, volume of bone graft placed intraoperatively, ESWT settings, pain medication utilization, length of stay (LOS), follow-up, cone beam computed tomography (CBCT) data, and complications were recorded. Results: Twenty patients met inclusion criteria. Median age at surgery was 9 years (range 8-16). Four (20%) patients were female; 16 (80%) were male. Eight (40%) patients had bilateral alveolar clefts; 12 (60%) had unilateral clefts. All (100%) patients were discharged on the day of surgery. Twelve (60%) patients required a median of 1.3 oxycodone doses post-operatively (range 0-6.5). All patients received ESWT treatments intra and post-operatively. All patients demonstrated an increase in bone graft volume visualized on CBCT: median increase of 6.8% (range 1.3%-35.7%) between 106.5 days (17.5% of ideal visualized, range 5%-42%) and 245.5 days (27.9% of ideal, range 8%-55.7%). Three (15%) patients experienced minor complications. Conclusions: Initial outcomes suggest that ESWT may expedite visualization of bone consolidation and facilitate recovery without increasing complications. ESWT could further represent an opportunity to improve care in craniofacial surgery. Pertinent considerations, the role of standardized assessment protocols, and future directions will be reviewed.","PeriodicalId":93749,"journal":{"name":"FACE (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136211192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
FACE (Thousand Oaks, Calif.)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1