Aliyu Samaila, Aminu A Biambo, Nuruddeen Usman, Usman M Aliyu, Adamu Abdullahi, Maxwell O Adibe
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引用次数: 0
Abstract
Background: There are important consequences from cervical cancer (CC) disease and its treatment among survivors, especiallythe impact on quality of life (QoL).
Objective: To evaluate the health-related QoL associated with different CC therapies received by patients in two Nigerian tertiaryhospitals.
Methods: This study employed a prospective longitudinal design. It was conducted at Usmanu Danfodiyo University TeachingHospital, Sokoto and Ahmadu Bello University Teaching Hospital Zaria, North-Western Nigeria. Data of all the 157 eligible CCpatients were collected at baseline and after therapy. Data analysis was done with appropriate descriptive and inferential statisticsusing SPSS V. 20 for windows. P<0.05 was considered statistically significant.
Results: Chemotherapy (CT) was the major therapy option received by 78(49.7%) of the patients. Patients who received chemoradiation therapy (CRT) and adjuvant chemotherapy (CTS) had the highest increase in mean overall health-related QoL of 0.138(t=8.456, p<0.001) and 0.138 (t=6.489, p<0.001) higher than their respective baseline scores. Patients who received CT had theleast increase in mean overall health-related QoL of 0.095 (t=4.574, p<0.001) from baseline.
Conclusion: Chemoradiation therapy and adjuvant chemotherapy were associated with highest increase in mean overallhealth-related QoL. Chemotherapy was associated with the least increase in mean overall health-related QoL.
Keywords: Cervical cancer; quality of life; therapies.
期刊介绍：
The African Health Sciences is an internationally refereed journal publishing original articles on research, clinical practice, public health, policy, planning, implementation and evaluation, in the health and related sciences relevant to Africa and the tropics. Its objectives are to: Advocate for and promote the growth of reading culture in sub Saharan Africa; Provide a high quality journal in which health and policy and other researchers and practitioners in the region can and world wide, can publish their work; Promote relevant health system research and publication in the region including alternative means of health care financing, the burden of and solution of health problems in marginalized urban and rural communities amongst the displaced and others affected by conflict; Promote research and the systematic collection and collation and publication of data on diseases and conditions of equity and influence; Promote development of evidence-based policies and guidelines for clinical, public health and other practitioners. African Health Sciences acknowledges support provided by the African Health Journals Partnership Project that is funded by the US National Institutes of Health (through the National Library of Medicine and the Fogarty International Center) and facilitated by the Council of Science Editors.
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