To study the clinical course and management of recurrent OSSN in HIV positive patient in Eastern Uttar Pradesh

Aditi Jhunjhunwala, Kriti Bhatt
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Abstract

We present a case of recurrent OSSN in HIV positive individual and its successful management. Patient presented to us with slow growing painless greyish mass in temporal area in interpalpebral region. He was diagnosed with HIV 2 years back and was on HAART regimen. He underwent excision for a similar looking mass in same eye 2 years back at the same time he was diagnosed with HIV. On local examination, a greyish white raised nodular gelatinous mass with feeder vessel was seen. It did not involve cornea and took up staining with rose bengal stain. complete excision biopsy using no-touch technique with a margin clearance of 4 mm followed by mitomycin-C and the remaining conjunctival defect closed with amniotic membrane graft was done. Histopathology confirmed OSSN. No recurrence was seen at 2-year follow-up. HIV shows a strong relation with OSSN and also with recurrent disease. Histopathology should always be done in interpalpebral mass excision in HIV positive patients as the recurrence rate is higher with more aggressive tumour.
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目的:探讨北方邦东部地区HIV阳性患者复发性OSSN的临床病程及处理方法
我们报告一例HIV阳性个体复发性OSSN及其成功的治疗。患者向我们报告在眼睑间颞区有缓慢生长的无痛性灰色肿块。两年前,他被诊断出感染了艾滋病毒,并接受了HAART治疗。两年前,他在同一只眼睛里接受了一个类似肿块的手术,同时他被诊断出患有艾滋病。局部检查可见灰白色凸起的结节状胶状肿块伴输水血管。不累及角膜,采用玫瑰红染色。采用无接触技术完全切除活检,边缘间隙为4mm,然后使用丝裂霉素c,并用羊膜移植闭合剩余的结膜缺损。组织病理学证实为OSSN。随访2年未见复发。HIV与OSSN和复发性疾病有密切关系。由于肿瘤侵袭性越强,复发率越高,因此在HIV阳性患者的睑间肿块切除术中应进行组织病理学检查。
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