Qualitative Evaluation on the Use of Pneumonia Antibiotics for Covid-19 Patients at X Hospital Bali in 2020

Wirda Anggraini, Fitria Rahma Fauzia, Arief Suryadinata, Burhan Ma'arif, Ni Nyoman Sri Budayanti, Fransiska Rosari Dewi
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Abstract

Coronavirus disease-19 (Covid-19) is a pandemic that has caused various complications, including pneumonia. One of the therapies used in Covid-19 with pneumonia complications is antibiotics. Antibiotics must be used appropriately to prevent antibiotic resistance. A method to reduce the number of antibiotic resistances is evaluating the use of antibiotics qualitatively using the Gyssens method. Therefore, this study aims to describe the profile and rationality of using pneumonia antibiotics for adult Covid-19 patients at X Hospital from January to December 2020. The data was collected retrospectively on adult patients using the patient's medical record data, and the sample was determined using the purposive sampling technique. There were 117 samples of medical record data processed in this study. This study concluded that the use of antibiotics for patients with Covid-19 disease consisted of single antibiotic usage, i.e., azithromycin in 82 cases (70.09%), and levofloxacin in 30 cases (25.64%), and switched antibiotics usage, i.e., azithromycin to levofloxacin in 5 cases (4.27%). The rationality of using antibiotics using the Gyssens methods was 90.60% with rational or appropriate antibiotics use (category 0). Moreover, there was 9.40% irrational drug use (category I-VI), comprising antibiotics for a longer time than it should be, in 11 cases.
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巴厘X医院2020年新冠肺炎患者肺炎抗生素使用定性评价
冠状病毒病-19 (Covid-19)是一种引起各种并发症的大流行疾病,包括肺炎。在Covid-19合并肺炎并发症中使用的治疗方法之一是抗生素。必须适当使用抗生素,以防止抗生素耐药性。一种减少抗生素耐药数量的方法是使用Gyssens方法对抗生素的使用进行定性评估。因此,本研究旨在描述X医院2020年1 - 12月成人Covid-19患者肺炎抗生素使用情况及合理性。使用患者病历资料对成年患者进行回顾性收集,并采用有目的抽样技术确定样本。本研究共处理117份病历资料样本。本研究得出Covid-19患者抗生素使用情况为单一抗生素使用,阿奇霉素82例(70.09%),左氧氟沙星30例(25.64%),阿奇霉素与左氧氟沙星切换使用的抗生素5例(4.27%)。采用Gyssens方法使用抗生素的合理性为90.60%,合理或适当使用抗生素(0类),不合理使用(I-VI类)的比例为9.40%,其中11例不合理使用抗生素的时间超过了应使用的时间。
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