Phytochemical Screening, Evaluation and Comparative Study of the Antioxidant Activities of Leaves and Stem Bark Extracts from Anogeissus leiocarpus: A Plant Used in Traditional Medicine in Northern Ivory Coast

Ouattara Logopho Hyacinthe, Yoro Thierry Dezay, Bamba Souleymane, Mouho Guéi Didier Roselin, Patrick Audrey N’guessan, Yao Jean landry Koffi, Sigata Yéo, Doumadé Zon, Ahmont Landry Claude Kablan
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Abstract

Anogeissus leiocarpus is a medicinal plant from Ivory Coast. It would be traditionally used to treat several pathologies. The aim of this study was to confirm or refute the use of both leaves and stem bark in the prevention or treatment of diseases linked to oxidative stress. Phytochemical sorting in these two organs of Anogeissus leiocarpus showed the presence of flavonoids, coumarins, tannins, phenolic acids, sterols and terpenes. The radical DPPH scavenging activity was carried out qualitatively and quantitatively by thin layer chromatographic (TLC) and spectroscopic methods, respectively. Quantitative analysis by spectrophotometry showed that the antioxidant power of the stem bark is slightly higher than leaves. These organs could therefore be used as good antioxidants in the prevention and treatment of diseases linked to oxidative stress. However, works on safeness should contribute to the valorisation of these materials for giving in use as herbal drug accessible to all social classes.
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象牙海岸北部传统药用植物黑果皮叶、茎、皮提取物抗氧化活性的筛选、评价及比较研究
黑杖是一种产自象牙海岸的药用植物。传统上,它被用来治疗几种疾病。本研究的目的是证实或反驳叶和茎树皮在预防或治疗与氧化应激有关的疾病中的使用。这两个器官的植物化学分选结果显示,黄酮类、香豆素类、单宁类、酚酸类、甾醇类和萜类化合物均存在。采用薄层色谱(TLC)和光谱法对其自由基DPPH清除活性进行定性和定量研究。分光光度法定量分析表明,茎皮的抗氧化能力略高于叶。因此,这些器官可以用作预防和治疗与氧化应激有关的疾病的良好抗氧化剂。然而,安全性方面的工作应该有助于这些材料的增值,以便所有社会阶层都能使用这些材料作为草药。
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