Tunica Vaginalis Pedicle Flap Substitution Urethroplasty for Reconstruction of Anterior Urethral Stricture

None Moktadir Hossain Mridha, None Mohammad Shah Alam, None Md Maidul Islam, None Md Ali Ashraf, None K M Faisal Al Ahsan, None Amiya Dev Bhatta, None A K M Anwarul Islam
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Abstract

Background: In long-segment urethral stricture, substitutional urethroplasty is the best option to get long-term good results. Though buccal mucosa is the most widely used tissue, it has limitations in some oral pathology. In several publications, there is evidence that Tunica vaginalis can be used as a graft or flap to reconstruct fibrotic urethra as well as to provide a vascularized covering to prevent subsequent urethrocutaneous fistula formation. This study evaluated the efficacy of the tunica vaginalis pedicle flap’s efficacy for managing anterior urethral stricture.Objectives: To evaluate the clinical efficacy of tunica vaginalis pedicle flap for reconstruction of anterior urethral stricture by assessing change in the maximum flow rate (Qmax), International prostatic symptom index (IPSS), postvoid residual urine (PVR) from baseline and the complication of surgery.Materials and Methods: This was a prospective clinical trial conducted in the Department of Urology, Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2017 to June 2018. A total of 15 patients were selected from the study population according to inclusion and exclusion criteria. The standard operation technique of urethroplasty by tunica vaginalis flap was followed. Patients were followed up after 3 months & 6 months to evaluate IPPS score, Qmax, flow time, PVR, and complications.Results: The mean age and stricture length of study participants were 38.93±11.38 years and 3.55±1.05 cm. The maximum flow of urine was 15.844±3.80 ml/sec at the final follow up which showed statistically significant improvement from baseline. There was also a significant improvement in IPSS, and quality of life during follow-up. Flow time and post-void residue reduced significantly from preoperative measurement. A total of 4 patients developed complications after the substitution of urethroplasty with tunica vaginalis.Conclusion: Tunica vaginalis pedicle flap may be an effective choice in the reconstruction of anterior urethral stricture.KYAMC Journal Vol. 14, No. 02, July 2023: 79-82.
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阴道膜带蒂皮瓣替代尿道成形术治疗前尿道狭窄
背景:对于长段尿道狭窄,尿道置换成形术是获得长期良好效果的最佳选择。虽然口腔粘膜是应用最广泛的组织,但它在某些口腔病理上有局限性。在一些出版物中,有证据表明阴道膜可以用作移植物或皮瓣重建纤维化尿道,并提供血管化的覆盖物以防止随后的尿道瘘形成。本研究评价阴道膜蒂皮瓣治疗前尿道狭窄的疗效。目的:通过观察最大流速(Qmax)、国际前列腺症状指数(IPSS)、空后残留尿(PVR)较基线的变化及手术并发症,评价阴道膜蒂皮瓣重建前尿道狭窄的临床疗效。材料与方法:这是一项前瞻性临床试验,于2017年7月至2018年6月在达卡Bangabandhu Sheikh Mujib医科大学泌尿外科进行。根据纳入和排除标准,从研究人群中共选择15例患者。采用阴道膜瓣尿道成形术的标准手术技术。术后3个月随访。6个月评估IPPS评分、Qmax、血流时间、PVR和并发症。结果:研究参与者的平均年龄为38.93±11.38岁,狭窄长度为3.55±1.05 cm。最终随访时最大尿流量为15.844±3.80 ml/sec,较基线有统计学显著改善。在随访期间,IPSS和生活质量也有显著改善。与术前测量相比,流动时间和空隙后残留明显减少。阴道膜替代尿道成形术后出现并发症4例。结论:阴道膜蒂皮瓣可能是前尿道狭窄重建的有效选择。KYAMC学报,第14卷,第02期,2023年7月:79-82。
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