Anterior segment optical coherence tomography parameters in subtypes of primary angle closure glaucoma

Sara Salah Abd Elrahman Dabour, Ahmed Fekry Almaria, Tarek Ragaie Hussien, Tarek El-Mohammadi Eid
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Abstract

Background: Anterior segment optical coherence tomography (AS-OCT) offers a non-contact method for high resolution cross-sectional imaging of the anterior segment and its structures by measuring their optical reflections. This project's objective was to research the significant value of ASـOCT parameters in subtypes of primary angle closure glaucoma (PACG). Methods: This is an observational, prospective cross-sectional research on 60 eyes of patients with PACG. There were three distinct groups of patients: Group (PACS) (n=18): primary angle closure suspect. Group (PAC) (n=18): primary angle closure. Group (PACG) (n=24): PACGResults: Angle Opening Distance (AOD) 500 NAS and Trabecular-Iris Contact Length (TICL) NAS discrepancies across the groups (p1, p2 and p3) were statistically different. In the group P1, there were substantial variations in iris thickness measured by the 750 Trabecular Meshwork (TEM). In the PACG and PAC groups, respectively, there was a highly significant negative connection between the lens vault and the AC depth and width. The lens vault and TICL at the temporal angle had a substantial negative association in the PAC group and an elevated correlation in the PACG group. Cup-to-disc (C/D) ratio, lens vault, AOD500 at nasal angle, Iris curve at nasal and temporal angle, Iris thickness at temporal angle, TICL at both temporal and nasal angle are predictor parameters in subtypes of primary angle closure.Conclusions: ASOCT can be used to assess anterior chamber angle. AS-OCT has a role to determine which parameters are the strongest predictive factors of subtypes of PAC. AS-OCT will be employed as a diagnostic tool for glaucoma patients' diagnosis and maybe their therapy.
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原发性闭角型青光眼亚型的前段光学相干断层成像参数
背景:前段光学相干断层扫描(AS-OCT)通过测量前段及其结构的光学反射,提供了一种非接触的高分辨率横断面成像方法。本项目的目的是研究ASـOCT参数在原发性闭角型青光眼(PACG)亚型中的重要价值。方法:对60只眼PACG患者进行观察性、前瞻性横断面研究。患者分为三组:PACS组(n=18):怀疑原发性闭角。PAC组(n=18):主角闭合。PACG组(n=24): PACG结果:各组间(p1、p2、p3)的角度开口距离(AOD) 500 NAS和小梁-虹膜接触长度(TICL) NAS差异有统计学意义。在P1组中,通过750小梁网(TEM)测量的虹膜厚度有实质性变化。在PACG组和PAC组中,晶状体穹窿与AC深度和宽度呈极显著负相关。晶状体穹窿与颞角TICL在PAC组呈显著负相关,在PACG组相关性升高。杯盘比(C/D)、晶状体穹窿、鼻角AOD500、鼻和颞角虹膜曲线、颞角虹膜厚度、颞和鼻角TICL是原发性闭角亚型的预测参数。结论:ASOCT可用于评估前房角。as - oct可以确定哪些参数是PAC亚型的最强预测因素。as - oct将被用作青光眼患者的诊断和治疗的诊断工具。
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