The Impact of Advanced Maternal Age on Neonatal Outcome in Preterm Births before 34 Weeks

IF 0.4 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Clinical and experimental obstetrics & gynecology Pub Date : 2023-09-20 DOI:10.31083/j.ceog5009191
Daniel Tairy, Ohad Gluck, Yakira Izaik, Jacob Bar, Eran Weiner, Giulia Barda
{"title":"The Impact of Advanced Maternal Age on Neonatal Outcome in Preterm Births before 34 Weeks","authors":"Daniel Tairy, Ohad Gluck, Yakira Izaik, Jacob Bar, Eran Weiner, Giulia Barda","doi":"10.31083/j.ceog5009191","DOIUrl":null,"url":null,"abstract":"Background: In recent years a trend towards childbearing at older maternal age is evident. Most of the current literature investigated the association between advanced maternal age and neonatal outcome at term. We aimed to study the outcomes of the mother and the neonate among preterm births of women of advanced maternal age. Methods: This retrospective study between 2009 to 2017, comprised 494 singleton preterm births between 24 and 34 weeks gestation, of which 116 (23%) were of 35 years old or older (advanced maternal age) and 378 (77%) were of younger women. The medical records were reviewed and the outcomes of the mother and the neonate were compared between advanced maternal age (≥35 years) and younger women. Results: The rate of severe intra-ventricular hemorrhage (IVH) and of composite adverse neonatal outcome was lower among advanced maternal age women compared to younger women (p = 0.02 and p = 0.05 respectively). In multivariate regression analysis, composite adverse neonatal outcome was found to be independently inversely associated only with advanced maternal age (adjusted odds ratio (aOR) 0.45 95% confidence interval (CI) 0.23–0.86). Conclusions: Advanced maternal age was not found to be a risk factor for adverse neonatal outcome among preterm births before 34 weeks, and might be a protective factor from early neonatal complications.","PeriodicalId":10312,"journal":{"name":"Clinical and experimental obstetrics & gynecology","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and experimental obstetrics & gynecology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31083/j.ceog5009191","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: In recent years a trend towards childbearing at older maternal age is evident. Most of the current literature investigated the association between advanced maternal age and neonatal outcome at term. We aimed to study the outcomes of the mother and the neonate among preterm births of women of advanced maternal age. Methods: This retrospective study between 2009 to 2017, comprised 494 singleton preterm births between 24 and 34 weeks gestation, of which 116 (23%) were of 35 years old or older (advanced maternal age) and 378 (77%) were of younger women. The medical records were reviewed and the outcomes of the mother and the neonate were compared between advanced maternal age (≥35 years) and younger women. Results: The rate of severe intra-ventricular hemorrhage (IVH) and of composite adverse neonatal outcome was lower among advanced maternal age women compared to younger women (p = 0.02 and p = 0.05 respectively). In multivariate regression analysis, composite adverse neonatal outcome was found to be independently inversely associated only with advanced maternal age (adjusted odds ratio (aOR) 0.45 95% confidence interval (CI) 0.23–0.86). Conclusions: Advanced maternal age was not found to be a risk factor for adverse neonatal outcome among preterm births before 34 weeks, and might be a protective factor from early neonatal complications.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
高龄产妇对34周前早产儿新生儿结局的影响
背景:近年来高龄生育趋势明显。目前的大多数文献调查了高龄产妇与足月新生儿结局之间的关系。我们的目的是研究高龄产妇早产中母亲和新生儿的结局。方法:2009年至2017年的回顾性研究,纳入494例妊娠24 - 34周的单胎早产儿,其中116例(23%)为35岁及以上(高龄产妇),378例(77%)为年轻女性。回顾医疗记录,比较高龄产妇(≥35岁)和年轻产妇的母婴结局。结果:高龄产妇的严重脑室内出血(IVH)发生率和新生儿综合不良结局发生率均低于年轻产妇(p = 0.02和p = 0.05)。在多因素回归分析中,复合新生儿不良结局仅与高龄产妇存在独立负相关(调整优势比(aOR) 0.45, 95%可信区间(CI) 0.23-0.86)。结论:未发现高龄产妇是34周前早产儿不良新生儿结局的危险因素,可能是早期新生儿并发症的保护因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
0.50
自引率
0.00%
发文量
241
审稿时长
1 months
期刊介绍: CEOG is an international, peer-reviewed, open access journal. CEOG covers all aspects of Obstetrics and Gynecology, including obstetrics, prenatal diagnosis, maternal-fetal medicine, perinatology, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine, infertility, reproductive endocrinology, sexual medicine. All submissions of cutting-edge advances of medical research in the area of women''s health worldwide are encouraged.
期刊最新文献
Maternal Deaths in Kayseri: Causes and Risk Factors The Relationship between Nifedipine and Postpartum Blood Loss in Patients with Preterm Labor Add-Back and Combined Regulation in GnRH-a Treatment of Endometriosis The Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Procedures in Contemporary Gynecology: An Appraisal of the Published Evidence and a Review A Retrospective Study Comparing of Group B Streptococcus Invasiveness in Pregnant Women and Infants
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1