A STOCHASTIC DIFFERENTIAL EQUATION (SDE) BASED MODEL FOR THE SPREAD OF TUBERCULOSIS

Otache Innocent Ogwuche, Ephraim Kator Iortyer, Alex Emonyi, Michael Ali
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Abstract

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. In this work, a deterministic and stochastic model of the transmission dynamics of Tuberculosis is developed and analyzed. The models involve the Susceptible, Exposed, Infectious and Recovered individuals. We computed the basic reproduction number and showed that for, the disease-free equilibrium is globally asymptotically stable. The resulting deterministic model was transformed into an equivalent stochastic model resulting in stochastic differential equation. The drift coefficient, the covariance matrix and the diffusion matrix were determined using the method proposed by Allen et al. (2008).
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基于随机微分方程(sde)的结核病传播模型
了解传染病的动力学有助于设计适当的策略来控制其在人群中的传播。在这项工作中,开发和分析了结核病传播动力学的确定性和随机模型。这些模型包括易感个体、暴露个体、感染个体和康复个体。我们计算了基本繁殖数,并证明对于,无病平衡是全局渐近稳定的。将确定性模型转化为等效随机模型,得到随机微分方程。漂移系数、协方差矩阵和扩散矩阵采用Allen et al.(2008)提出的方法确定。
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